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Zymeworks
ZYME

Overview Fund Activity

180 hedge funds and large institutions have $949M invested in Zymeworks in 2025 Q2 according to their latest regulatory filings, with 29 funds opening new positions, 62 increasing their positions, 55 reducing their positions, and 30 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
180
Holders Change
-3
Holders Change %
-1.64%
% of All Funds
2.42%
Holding in Top 10
5
Holding in Top 10 Change
–
Holding in Top 10 Change %
–
% of All Funds
0.07%
New
29
Increased
62
Reduced
55
Closed
30
Calls
$4.2M
Puts
$883K
Net Calls
+$3.32M
Net Calls Change
+$154K

Top Buyers

1
EC
1
EcoR1 Capital
California
$288M
2
Vanguard Group
2
Vanguard Group
Pennsylvania
$30.9M
3
VPC
3
Vestal Point Capital
New York
$14.4M
4
Adage Capital Partners
4
Adage Capital Partners
Massachusetts
$5.97M
5
NL
5
Nuveen LLC
North Carolina
$8.22M

Top Sellers

1
UBS AM
1
UBS AM
Illinois
$30.9M
2
BCM
2
Bridgeway Capital Management
Texas
$0
3
RG
3
Redmile Group
California
$52.1M
4
PA
4
Perceptive Advisors
New York
$16M
5
FCM
5
Farallon Capital Management
California
$0
Name Holding Trade Value Shares
Change 		Shares
Change %
CA
176
CoreCap Advisors
Michigan
$226 – – –
Northwestern Mutual Wealth Management
177
Northwestern Mutual Wealth Management
Wisconsin
$176 +$176 +14 New
SS
178
SBI Securities
Japan
$126 – – –
TWD
179
True Wealth Design
Ohio
$88 -$163 -13 -65%
BCM
180
Bridgeway Capital Management
Texas
– -$9.13M -766,944 Closed
FCM
181
Farallon Capital Management
California
– -$4.76M -400,000 Closed
EF
182
Empowered Funds
Pennsylvania
– -$4.29M -360,044 Closed
Walleye Capital
183
Walleye Capital
New York
– -$2.95M -247,959 Closed
Verition Fund Management
184
Verition Fund Management
Connecticut
– -$1.36M -114,156 Closed
Voloridge Investment Management
185
Voloridge Investment Management
Florida
– -$1.14M -95,394 Closed
ACM
186
Aquilo Capital Management
California
– -$1.01M -84,482 Closed
ACM
187
ADAR1 Capital Management
Texas
– -$596K -50,000 Closed
HS
188
HighVista Strategies
Massachusetts
– -$496K -41,607 Closed
Franklin Resources
189
Franklin Resources
California
– -$383K -32,160 Closed
CF
190
Corebridge Financial
Texas
– -$318K -26,719 Closed
SSA
191
Schonfeld Strategic Advisors
New York
– -$261K -21,900 Closed
SFI
192
Susquehanna Fundamental Investments
Pennsylvania
– -$204K -17,090 Closed
CWM
193
CIBC World Markets
New York
– -$144K -12,102 Closed
Jacobs Levy Equity Management
194
Jacobs Levy Equity Management
New Jersey
– -$143K -12,040 Closed
OWA
195
One Wealth Advisors
California
– -$124K -10,404 Closed
ETC
196
Exchange Traded Concepts
Oklahoma
– -$121K -10,126 Closed
Lazard Asset Management
197
Lazard Asset Management
New York
– -$45K -3,787 Closed
ACM
198
Aquatic Capital Management
Illinois
– -$24.4K -2,049 Closed
WF
199
Wayfinding Financial
Washington
– -$11K -981 Closed
SAM
200
Smartleaf Asset Management
Massachusetts
– -$4.96K -401 Closed
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