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Zymeworks
ZYME

Overview Fund Activity

180 hedge funds and large institutions have $949M invested in Zymeworks in 2025 Q2 according to their latest regulatory filings, with 29 funds opening new positions, 62 increasing their positions, 55 reducing their positions, and 30 closing their positions.

Holders
180
Holders Change
-3
Holders Change %
-1.64%
% of All Funds
2.42%
Holding in Top 10
5
Holding in Top 10 Change
–
Holding in Top 10 Change %
–
% of All Funds
0.07%
New
29
Increased
62
Reduced
55
Closed
30
Calls
$4.2M
Puts
$883K
Net Calls
+$3.32M
Net Calls Change
+$154K

Top Buyers

1
EC
1
EcoR1 Capital
California
$288M
2
Vanguard Group
2
Vanguard Group
Pennsylvania
$30.9M
3
VPC
3
Vestal Point Capital
New York
$14.4M
4
Adage Capital Partners
4
Adage Capital Partners
Massachusetts
$5.97M
5
NL
5
Nuveen LLC
North Carolina
$8.22M

Top Sellers

1
UBS AM
1
UBS AM
Illinois
$30.9M
2
BCM
2
Bridgeway Capital Management
Texas
$0
3
RG
3
Redmile Group
California
$52.1M
4
PA
4
Perceptive Advisors
New York
$16M
5
FCM
5
Farallon Capital Management
California
$0
Name Holding Trade Value Shares
Change 		Shares
Change %
CIAM
151
Caitong International Asset Management
Hong Kong
$7.08K +$7.08K +564 New
Osaic Holdings
152
Osaic Holdings
Arizona
$6.21K +$347 +24 +6%
National Bank of Canada
153
National Bank of Canada
Quebec, Canada
$5.92K -$652 -52 -10%
PNC Financial Services Group
154
PNC Financial Services Group
Pennsylvania
$4.24K +$1.36K +108 +47%
PA
155
Parallel Advisors
California
$4.13K – – –
Daiwa Securities Group
156
Daiwa Securities Group
Japan
$4K – – –
TC
157
Truvestments Capital
Florida
$3.88K – – –
TWC
158
TD Waterhouse Canada
Ontario, Canada
$3.85K – – –
HWM
159
HighMark Wealth Management
Minnesota
$3.51K – – –
US Bancorp
160
US Bancorp
Minnesota
$3.11K -$2.2K -175 -41%
EWA
161
EverSource Wealth Advisors
Alabama
$2.27K +$2.11K +168 +1,292%
AF
162
Allworth Financial
California
$1.53K +$151 +12 +11%
SCM
163
Sterling Capital Management
North Carolina
$1.49K -$10.3K -822 -87%
BIG
164
Brooklyn Investment Group
New York
$1.39K -$2.24K -178 -62%
Group One Trading
165
Group One Trading
Illinois
$1.26K – – –
IA
166
IFP Advisors
Florida
$1.21K +$1.21K +96 New
PD
167
Point72 (DIFC)
United Arab Emirates
$966 +$966 +77 New
KG
168
Kilter Group
New York
$829 +$829 +66 New
RIL
169
Rothschild Investment LLC
Illinois
$690 -$565 -45 -45%
SPIA
170
Steward Partners Investment Advisory
New York
$665 – – –
PWA
171
Physician Wealth Advisors
Utah
$641 +$641 +51 New
BFS
172
Bare Financial Services
Pennsylvania
$565 +$565 +45 New
CPG
173
Cornerstone Planning Group
New Jersey
$439 +$439 +35 New
FFA
174
Farther Finance Advisors
California
$314 -$1.43K -114 -82%
AG
175
AmeriFlex Group
Nevada
$247 – – –
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7
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