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Zymeworks
ZYME

Overview Fund Activity

178 hedge funds and large institutions have $942M invested in Zymeworks in 2025 Q2 according to their latest regulatory filings, with 29 funds opening new positions, 62 increasing their positions, 53 reducing their positions, and 30 closing their positions.

Holders
178
Holders Change
-5
Holders Change %
-2.73%
% of All Funds
2.39%
Holding in Top 10
5
Holding in Top 10 Change
–
Holding in Top 10 Change %
–
% of All Funds
0.07%
New
29
Increased
62
Reduced
53
Closed
30
Calls
$3.35M
Puts
$208K
Net Calls
+$3.14M
Net Calls Change
-$26K

Top Buyers

1
EC
1
EcoR1 Capital
California
$288M
2
Vanguard Group
2
Vanguard Group
Pennsylvania
$30.9M
3
VPC
3
Vestal Point Capital
New York
$14.4M
4
Adage Capital Partners
4
Adage Capital Partners
Massachusetts
$5.97M
5
NL
5
Nuveen LLC
North Carolina
$8.22M

Top Sellers

1
UBS AM
1
UBS AM
Illinois
$30.9M
2
BCM
2
Bridgeway Capital Management
Texas
$0
3
RG
3
Redmile Group
California
$52.1M
4
PA
4
Perceptive Advisors
New York
$16M
5
FCM
5
Farallon Capital Management
California
$0
Name Market Value Shares Shares
Change 		Shares
Change %
DWAM
101
Duncan Williams Asset Management
Tennessee
$277K 22,095 – –
State of Wisconsin Investment Board
102
State of Wisconsin Investment Board
Wisconsin
$277K 22,035 -15,789 -42%
GCM
103
Graham Capital Management
Connecticut
$272K 21,660 +21,660 New
Mackenzie Financial
104
Mackenzie Financial
Ontario, Canada
$268K 21,355 +21,355 New
Manulife (Manufacturers Life Insurance)
105
Manulife (Manufacturers Life Insurance)
Ontario, Canada
$239K 19,070 -1,390 -7%
EGM
106
Engineers Gate Manager
New York
$238K 18,941 +6,542 +53%
Janus Henderson Group
107
Janus Henderson Group
United Kingdom
$229K 18,200 – –
CAM
108
Cresset Asset Management
Illinois
$209K 16,638 -4,682 -22%
State Board of Administration of Florida Retirement System
109
State Board of Administration of Florida Retirement System
Florida
$193K 15,340 – –
CCIA
110
Campbell & Co Investment Adviser
Maryland
$188K 14,985 +14,985 New
VOYA Investment Management
111
VOYA Investment Management
Georgia
$187K 14,887 -766 -5%
Envestnet Asset Management
112
Envestnet Asset Management
Illinois
$183K 14,606 -34,906 -71%
Universal-Beteiligungs- und Servicegesellschaft
113
Universal-Beteiligungs- und Servicegesellschaft
Germany
$179K 14,300 +14,300 New
IC
114
IEQ Capital
California
$178K 14,169 +14,169 New
A
115
AlphaQuest
New York
$176K 14,026 -17,650 -56%
CUAMC
116
China Universal Asset Management Company
China
$176K 13,996 +180 +1%
New York State Common Retirement Fund
117
New York State Common Retirement Fund
New York
$168K 13,371 – –
ProShare Advisors
118
ProShare Advisors
Maryland
$159K 12,665 -2,247 -15%
Jane Street
119
Jane Street
New York
$157K 12,549 -123,214 -91%
MF
120
Magnetar Financial
Illinois
$153K 12,168 -280 -2%
QCM
121
Quantinno Capital Management
New York
$147K 11,746 -2,499 -18%
PFSRSONJ
122
Police & Firemen's Retirement System of New Jersey
New Jersey
$146K 11,669 – –
Janney Montgomery Scott
123
Janney Montgomery Scott
Pennsylvania
$145K 11,567 – –
ASRS
124
Arizona State Retirement System
Arizona
$140K 11,159 -687 -6%
BHCM
125
Brevan Howard Capital Management
Jersey
$133K 10,628 +10,628 New
3 4
5
6 7