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Zymeworks
ZYME

Overview Fund Activity

178 hedge funds and large institutions have $942M invested in Zymeworks in 2025 Q2 according to their latest regulatory filings, with 29 funds opening new positions, 62 increasing their positions, 53 reducing their positions, and 30 closing their positions.

Holders
178
Holders Change
-5
Holders Change %
-2.73%
% of All Funds
2.39%
Holding in Top 10
5
Holding in Top 10 Change
–
Holding in Top 10 Change %
–
% of All Funds
0.07%
New
29
Increased
62
Reduced
53
Closed
30
Calls
$3.35M
Puts
$208K
Net Calls
+$3.14M
Net Calls Change
-$26K

Top Buyers

1
EC
1
EcoR1 Capital
California
$288M
2
Vanguard Group
2
Vanguard Group
Pennsylvania
$30.9M
3
VPC
3
Vestal Point Capital
New York
$14.4M
4
Adage Capital Partners
4
Adage Capital Partners
Massachusetts
$5.97M
5
NL
5
Nuveen LLC
North Carolina
$8.22M

Top Sellers

1
UBS AM
1
UBS AM
Illinois
$30.9M
2
BCM
2
Bridgeway Capital Management
Texas
$0
3
RG
3
Redmile Group
California
$52.1M
4
PA
4
Perceptive Advisors
New York
$16M
5
FCM
5
Farallon Capital Management
California
$0
Name Market Value Shares Shares
Change 		Shares
Change %
Charles Schwab
51
Charles Schwab
California
$1.56M 124,204 -9,435 -7%
Barclays
52
Barclays
United Kingdom
$1.54M 122,820 +47,390 +63%
CSS
53
Cubist Systematic Strategies
Connecticut
$1.51M 119,962 +119,962 New
AG
54
Algert Global
California
$1.48M 118,104 +118,104 New
Millennium Management
55
Millennium Management
New York
$1.46M 116,102 -179,504 -61%
DFCM
56
Dark Forest Capital Management
Puerto Rico
$1.22M 96,989 -8,840 -8%
NGM
57
North Growth Management
British Columbia, Canada
$1.22M 97,000 – –
Bank of America
58
Bank of America
North Carolina
$1.13M 90,378 +28,247 +45%
Invesco
59
Invesco
Georgia
$1.12M 89,371 +11,165 +14%
RhumbLine Advisers
60
RhumbLine Advisers
Massachusetts
$1.08M 86,083 +3,345 +4%
SPS
61
Susquehanna Portfolio Strategies
Pennsylvania
$1.08M 85,728 +85,728 New
ACP
62
Acuta Capital Partners
California
$1.05M 83,655 +15,196 +22%
Swiss National Bank
63
Swiss National Bank
Switzerland
$917K 73,100 -7,000 -9%
Royal Bank of Canada
64
Royal Bank of Canada
Ontario, Canada
$915K 72,983 +16,212 +29%
Fisher Asset Management
65
Fisher Asset Management
Washington
$903K 71,979 +5 +0%
Qube Research & Technologies (QRT)
66
Qube Research & Technologies (QRT)
United Kingdom
$877K 69,874 +69,874 New
Stifel Financial
67
Stifel Financial
Missouri
$875K 69,730 +2,700 +4%
WAM
68
Weiss Asset Management
Massachusetts
$680K 54,171 +54,171 New
VRS
69
Virginia Retirement Systems
Virginia
$679K 54,075 +9,900 +22%
TE
70
Tema ETFs
New York
$651K 51,855 +18,854 +57%
NIM
71
NEOS Investment Management
Connecticut
$651K 51,855 +18,854 +57%
ECM
72
ExodusPoint Capital Management
New York
$648K 51,669 -81,651 -61%
AllianceBernstein
73
AllianceBernstein
Tennessee
$628K 50,030 – –
SO
74
STRS Ohio
Ohio
$581K 46,300 +46,300 New
Prudential Financial
75
Prudential Financial
New Jersey
$564K 44,965 +2,395 +6%
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