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Tyra Biosciences

133 hedge funds and large institutions have $1.49B invested in Tyra Biosciences in 2025 Q4 according to their latest regulatory filings, with 29 funds opening new positions, 43 increasing their positions, 38 reducing their positions, and 10 closing their positions.

New
Increased
Maintained
Reduced
Closed

more call options, than puts

Call options by funds: $ | Put options by funds: $

more first-time investments, than exits

New positions opened: | Existing positions closed:

more funds holding in top 10

Funds holding in top 10:

more capital invested

Capital invested by funds: $ → $

15% more funds holding

Funds holding: 116133 (+17)

13% more repeat investments, than reductions

Existing positions increased: 43 | Existing positions reduced: 38

2.08% more ownership

Funds ownership: 104.39%106.47% (+2.1%)

Holders
133
Holders Change
Holders Change %
% of All Funds
Holding in Top 10
13
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
New
Increased
Reduced
Closed
Calls
$334K
Puts
$5K
Net Calls
Net Calls Change

Top Buyers

1 +$17M
2 +$10.9M
3 +$7.32M
4
State Street
State Street
Massachusetts
+$5.9M
5
CP
Caligan Partners
New York
+$4.54M

Top Sellers

1 -$28M
2 -$14.1M
3 -$4.72M
4
CPX
Canaan Partners XI
California
-$4.29M
5
Walleye Capital
Walleye Capital
New York
-$4.17M
Name Holding Trade Value Shares
Change
Change in
Stake
Creative Planning
76
Creative Planning
Kansas
$515K
Victory Capital Management
77
Victory Capital Management
Texas
$494K
Ohio Public Employees Retirement System (OPERS)
78
Ohio Public Employees Retirement System (OPERS)
Ohio
$487K
Deutsche Bank
79
Deutsche Bank
Germany
$431K
Rafferty Asset Management
80
Rafferty Asset Management
New York
$406K
MIM
81
MetLife Investment Management
New Jersey
$404K
T. Rowe Price Associates
82
T. Rowe Price Associates
Maryland
$380K
Russell Investments Group
83
Russell Investments Group
United Kingdom
$342K
Franklin Resources
84
Franklin Resources
California
$341K
Mirae Asset Global ETFs Holdings
85
Mirae Asset Global ETFs Holdings
Hong Kong
$339K
Fidelity Investments
86
Fidelity Investments
Massachusetts
$330K
VIA
87
Virtus Investment Advisers
Connecticut
$309K
Bank of Nova Scotia
88
Bank of Nova Scotia
Ontario, Canada
$292K
BBA
89
Baker Bros. Advisors
New York
$279K
IIM
90
INTECH Investment Management
Florida
$258K
VC
91
VarCov Co
Connecticut
$255K
CUAMC
92
China Universal Asset Management Company
China
$229K
Manulife (Manufacturers Life Insurance)
93
Manulife (Manufacturers Life Insurance)
Ontario, Canada
$220K
New York State Common Retirement Fund
94
New York State Common Retirement Fund
New York
$195K
PFSRSONJ
95
Police & Firemen's Retirement System of New Jersey
New Jersey
$169K
Citigroup
96
Citigroup
New York
$100K
BG
97
Bellevue Group
Switzerland
$82.6K
CIAM
98
Caitong International Asset Management
Hong Kong
$78.8K
Mirae Asset Global Investments
99
Mirae Asset Global Investments
South Korea
$68.2K
Legal & General Group
100
Legal & General Group
United Kingdom
$62.2K