SPRB

Spruce Biosciences, Inc. Common Stock
SPRB

Overview Fund Activity

30 hedge funds and large institutions have $3.02M invested in Spruce Biosciences, Inc. Common Stock in 2025 Q1 according to their latest regulatory filings, with 5 funds opening new positions, 5 increasing their positions, 7 reducing their positions, and 5 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
30
Holders Change
–
Holders Change %
0%
% of All Funds
0.41%
Holding in Top 10
–
Holding in Top 10 Change
–
Holding in Top 10 Change %
–
% of All Funds
–
New
5
Increased
5
Reduced
7
Closed
5
Calls
–
Puts
–
Net Calls
–
Net Calls Change
–

Top Buyers

1
TSS
Two Sigma Securities
New York
+$13.8K
2
VF
Virtu Financial
New York
+$11K
3
Jane Street
Jane Street
New York
+$10.9K
4
UBS Group
UBS Group
Switzerland
+$8.82K
5
GSC
Ground Swell Capital
South Carolina
+$5.02K

Top Sellers

1
SCV
Sands Capital Ventures
Virginia
-$301K
2
Susquehanna International Group
Susquehanna International Group
Pennsylvania
-$24.8K
3
HF
HRT Financial
New York
-$15K
4
BCM
Bridgeway Capital Management
Texas
-$14.7K
5
Northern Trust
Northern Trust
Illinois
-$13.8K
Name Holding Trade Value Shares
Change 		Shares
Change %
CG
1
Carlyle Group
District of Columbia
$840K – – –
RSCM
2
Rock Springs Capital Management
Maryland
$757K – – –
Acadian Asset Management
3
Acadian Asset Management
Massachusetts
$301K – – –
IC
4
Ikarian Capital
Texas
$290K – – –
Vanguard Group
5
Vanguard Group
Pennsylvania
$245K – – –
ACM
6
ADAR1 Capital Management
Texas
$117K – – –
Renaissance Technologies
7
Renaissance Technologies
New York
$111K -$6.67K -23,000 -6%
BFM
8
Boothbay Fund Management
New York
$83.8K – – –
Geode Capital Management
9
Geode Capital Management
Massachusetts
$80.3K +$848 +2,923 +1%
BlackRock
10
BlackRock
New York
$36.2K – – –
UBS Group
11
UBS Group
Switzerland
$33.8K +$8.82K +30,419 +35%
LPC
12
Lion Point Capital
New York
$21.8K – – –
State Street
13
State Street
Massachusetts
$17.6K – – –
TSS
14
Two Sigma Securities
New York
$13.8K +$13.8K +47,686 New
XT
15
XTX Topco
Cayman Islands
$12K +$1.64K +5,668 +16%
SC
16
Shay Capital
New York
$11.1K – – –
VF
17
Virtu Financial
New York
$11K +$11K +39,426 New
Jane Street
18
Jane Street
New York
$10.9K +$10.9K +37,429 New
Northern Trust
19
Northern Trust
Illinois
$9.49K -$13.8K -47,587 -59%
Two Sigma Investments
20
Two Sigma Investments
New York
$5.96K -$21 -71 -0.3%
GSC
21
Ground Swell Capital
South Carolina
$5.02K +$5.02K +17,312 New
Two Sigma Advisers
22
Two Sigma Advisers
New York
$3.54K -$464 -1,600 -12%
Citigroup
23
Citigroup
New York
$3.22K +$3.22K +11,083 New
Morgan Stanley
24
Morgan Stanley
New York
$2.15K +$1.53K +5,263 +247%
TRCT
25
Tower Research Capital (TRC)
New York
$1.36K -$19 -64 -1%
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