Spruce Biosciences
SPRB
57 hedge funds and large institutions have $80.4M invested in Spruce Biosciences in 2026 Q2 according to their latest regulatory filings, with 32 funds opening new positions, 14 increasing their positions, 3 reducing their positions, and 3 closing their positions.
967% more first-time investments, than exits
New positions opened: 32 | Existing positions closed: 3
367% more repeat investments, than reductions
Existing positions increased: 14 | Existing positions reduced: 3
78% more funds holding
Funds holding: 32 → 57 (+25)
66% more capital invested
Capital invested by funds: $48.3M → $80.4M (+$32.1M)
0.19% more ownership
Funds ownership: 53.92% → 54.1% (+0.19%)
0% more funds holding in top 10
Funds holding in top 10: 1 → 1 (0)
Top Buyers
| Rank | Fund | Capital Flow |
|---|---|---|
| 1 |
ACM
AIGH Capital Management
Baltimore,
Maryland
|
+$14M |
| 2 |
BlackRock
New York
|
+$9.55M |
| 3 |
Vanguard Capital Management
Malvern,
Pennsylvania
|
+$5.65M |
| 4 |
CCC
Cable Car Capital
San Francisco,
California
|
+$3.35M |
| 5 |
Geode Capital Management
Boston,
Massachusetts
|
+$3.22M |
Top Sellers
| Rank | Fund | Capital Flow |
|---|---|---|
| 1 |
Balyasny Asset Management
Chicago,
Illinois
|
-$1.56M |
| 2 |
Citadel Advisors
Miami,
Florida
|
-$1.01M |
| 3 |
SCM
Squadron Capital Management
Westmont,
Illinois
|
-$797K |
| 4 |
RCAP
Resolute Capital Asset Partners
Denver,
Colorado
|
-$261K |
| 5 |
SIS
Sound Income Strategies
Ft Lauderdale,
Florida
|
-$13.9K |
SPRB Hedge Fund Activity: Q2 2026 in Review
57 of the 8,153 institutional investors tracked by Wall St. Rank reported a position in Spruce Biosciences (SPRB) for Q2 2026, worth a combined $80.4M — up 66% from $48.3M a quarter earlier.
Buyers outnumbered sellers: 32 funds opened new SPRB positions and 3 closed out — a net gain of 29 holders — while 14 added to existing stakes and 3 trimmed.
The largest buyer was AIGH Capital Management, opening a new position worth an estimated $14M. The largest seller was Balyasny Asset Management, cutting an estimated $1.56M.
- 57 institutional investors held Spruce Biosciences (SPRB) as of Q2 2026, up from 32 in Q1 2026.
- Funds reported $80.4M of Spruce Biosciences stock for Q2 2026, up 66% quarter-over-quarter.
- 32 funds opened new Spruce Biosciences positions in Q2 2026 and 3 closed out, a net change of +29 holders.
- The largest Spruce Biosciences buyer in Q2 2026 was AIGH Capital Management, an estimated $14M added.
- The largest Spruce Biosciences seller in Q2 2026 was Balyasny Asset Management, an estimated $1.56M sold.
Based on aggregated 13F filings for Q2 2026.