Spruce Biosciences
SPRB
9 hedge funds and large institutions have $25.1M invested in Spruce Biosciences in 2025 Q3 according to their latest regulatory filings, with 7 funds opening new positions, increasing their positions, 1 reducing their positions, and 1 closing their positions.
17,049% more capital invested
Capital invested by funds: $147K → $25.1M (+$25M)
600% more first-time investments, than exits
New positions opened: 7 | Existing positions closed: 1
521.79% more ownership
Funds ownership: 0% → 521.79% (+522%)
200% more funds holding
Funds holding: 3 → 9 (+6)
100% less repeat investments, than reductions
Existing positions increased: 0 | Existing positions reduced: 1
Top Buyers
| Rank | Fund | Capital Flow |
|---|---|---|
| 1 |
CG
Carlyle Group
Washington,
District of Columbia
|
+$25.6M |
| 2 |
CCC
Cable Car Capital
San Francisco,
California
|
+$236K |
| 3 |
LPC
Lion Point Capital
New York
|
+$8.85K |
| 4 |
Osaic Holdings
Scottsdale,
Arizona
|
+$1.18K |
| 5 |
UBS Group
Zurich,
Switzerland
|
+$1.17K |
Top Sellers
| Rank | Fund | Capital Flow |
|---|---|---|
| 1 |
Acadian Asset Management
Boston,
Massachusetts
|
-$74K |
| 2 |
IC
Ikarian Capital
Dallas,
Texas
|
-$9 |
| Name | Holding | Trade Value |
Shares Change |
Change in Stake |
|
|---|---|---|---|---|---|
|
CG
1
Carlyle Group
Washington,
District of Columbia
| $24.8M | +$25.6M | +2,896,518 | New |
|
|
CCC
2
Cable Car Capital
San Francisco,
California
| $239K | +$236K | +26,666 | New |
|
|
IC
3
Ikarian Capital
Dallas,
Texas
| $119K | -$9 | -1 | -0% |
|
|
LPC
4
Lion Point Capital
New York
| $8.95K | +$8.85K | +1,000 | New |
|
|
5
UBS Group
Zurich,
Switzerland
| $1.18K | +$1.17K | +132 | New |
|
|
6
Osaic Holdings
Scottsdale,
Arizona
| $931 | +$1.18K | +133 | New |
|
7
Morgan Stanley
New York
| $878 | +$868 | +98 | New |
|
|
CSC
8
Caldwell Sutter Capital
Sausalito,
California
| $116 | – | – | – |
|
9
Bank of America
Charlotte,
North Carolina
| $27 | +$27 | +3 | New |
|
|
10
Acadian Asset Management
Boston,
Massachusetts
| – | -$74K | -13,944 | Closed |
|
SPRB Hedge Fund Activity: Q3 2025 in Review
9 of the 7,631 institutional investors tracked by Wall St. Rank reported a position in Spruce Biosciences (SPRB) for Q3 2025, worth a combined $25.1M — up 17,049% from $147K a quarter earlier.
Buyers outnumbered sellers: 7 funds opened new SPRB positions and 1 closed out — a net gain of 6 holders — while 0 added to existing stakes and 1 trimmed.
The largest buyer was Carlyle Group, opening a new position worth an estimated $25.6M. The largest seller was Acadian Asset Management, exiting entirely with an estimated $74K sold.
- 9 institutional investors held Spruce Biosciences (SPRB) as of Q3 2025, up from 3 in Q2 2025.
- Funds reported $25.1M of Spruce Biosciences stock for Q3 2025, up 17,049% quarter-over-quarter.
- 7 funds opened new Spruce Biosciences positions in Q3 2025 and 1 closed out, a net change of +6 holders.
- The largest Spruce Biosciences buyer in Q3 2025 was Carlyle Group, an estimated $25.6M added.
- The largest Spruce Biosciences seller in Q3 2025 was Acadian Asset Management, an estimated $74K sold.
Based on aggregated 13F filings for Q3 2025.