Jane Street’s Spruce Biosciences SPRB Stock Holding History

Jane Street’s Portfolio SPRB Stock Details SPRB Fund Activity

Bought

Maintained

Sold

Quarter	Market Value	Status	Shares	Change in Stake	Trade Value	Portfolio Weight	Portfolio Position
2025 Q2	–	Sell	-499	Closed	-$10.9K	–	11353
2025 Q1	$10.9K	Buy	+499	New	+$13.9K	﹤0.01%	9196
2024 Q4	–	Sell	-209	Closed	-$7.44K	–	10884
2024 Q3	$7.44K	Sell	209 -202	-49%	-$7.4K	﹤0.01%	9377
2024 Q2	$16K	Sell	411 -636	-61%	-$34.1K	﹤0.01%	9061
2024 Q1	$61.7K	Buy	+1,047	New	+$266K	﹤0.01%	8692
2022 Q1	–	Sell	-479	Closed	-$160K	–	11168
2021 Q4	$160K	Buy	+479	New	+$143K	﹤0.01%	8966

Other funds holding SPRB

Acadian Asset Management Boston, Massachusetts $70.5B AUM 36% 1-Year Est. Return

Ikarian Capital Dallas, Texas $1.23B AUM 600.17% 1-Year Est. Return

CSC

Caldwell Sutter Capital Sausalito, California $246M AUM 23.62% 1-Year Est. Return

Jane Street's SPRB Position: Q2 2025 in Review

Jane Street sold out of Spruce Biosciences (SPRB) in Q2 2025, closing a stake of 499 shares — an estimated $10.9K sold.

Jane Street first reported a position in SPRB in Q4 2021 and held it in 5 quarters. The position peaked at $160K in Q4 2021. 3 funds tracked by Wall St. Rank hold SPRB as of Q2 2025.

Jane Street reported no remaining Spruce Biosciences position as of Q2 2025 after selling out during the quarter.
Jane Street sold 499 Spruce Biosciences shares in Q2 2025, an estimated $10.9K.
Jane Street first reported a position in Spruce Biosciences in Q4 2021 and held it in 5 quarters.
Jane Street's Spruce Biosciences position peaked at $160K in Q4 2021.
3 funds tracked by Wall St. Rank held Spruce Biosciences as of Q2 2025.

Based on Jane Street's 13F filing for Q2 2025, filed 14 Aug 2025.