State Street
SPRB

State Street’s Spruce Biosciences SPRB Stock Holding History

State Street’s Portfolio SPRB Stock Details SPRB Fund Activity
Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake 		Trade Value Portfolio Weight Portfolio Position
2026
Q2 		$2.72M Buy
50,450
+45,050
+834% +$2.52M ﹤0.01% 3229
2026
Q1 		$353K Sell
5,400
-1,000
-16% -$69K ﹤0.01% 3739
2025
Q4 		$558K Buy
+6,400
New +$686K ﹤0.01% 3650
2025
Q2 		– Sell
-809
Closed -$17.6K – 4338
2025
Q1 		$17.6K Hold
809
– – ﹤0.01% 4222
2024
Q4 		$25.5K Sell
809
-50
-6% -$1.83K ﹤0.01% 4208
2024
Q3 		$30.6K Hold
859
– – ﹤0.01% 4170
2024
Q2 		$33.3K Hold
859
– – ﹤0.01% 4213
2024
Q1 		$50.6K Buy
859
+32
+4% +$8.14K ﹤0.01% 4156
2023
Q4 		$182K Hold
827
– – ﹤0.01% 3925
2023
Q3 		$140K Buy
827
+43
+5% +$7.25K ﹤0.01% 4027
2023
Q2 		$126K Sell
784
-457
-37% -$76.4K ﹤0.01% 4154
2023
Q1 		$206K Hold
1,241
– – ﹤0.01% 4070
2022
Q4 		$102K Hold
1,241
– – ﹤0.01% 4364
2022
Q3 		$128K Hold
1,241
– – ﹤0.01% 4354
2022
Q2 		$162K Sell
1,241
-1,498
-55% -$192K ﹤0.01% 4302
2022
Q1 		$413K Buy
2,739
+1,046
+62% +$195K ﹤0.01% 4127
2021
Q4 		$566K Sell
1,693
-11
-0.6% -$3.27K ﹤0.01% 3973
2021
Q3 		$768K Buy
1,704
+38
+2% +$23.9K ﹤0.01% 3844
2021
Q2 		$1.4M Buy
1,666
+403
+32% +$430K ﹤0.01% 3606
2021
Q1 		$1.57M Buy
1,263
+90
+8% +$138K ﹤0.01% 3521
2020
Q4 		$2.14M Buy
+1,173
New +$1.94M ﹤0.01% 3343

Other funds holding SPRB

ACM
AIGH Capital Management Baltimore, Maryland $1.59B AUM 855.46% 1-Year Est. Return
BlackRock
BlackRock New York $6.73T AUM 46.02% 1-Year Est. Return
IC
Ikarian Capital Dallas, Texas $928M AUM 596.14% 1-Year Est. Return
Vanguard Capital Management
Vanguard Capital Management Malvern, Pennsylvania $4.68T AUM
Geode Capital Management
Geode Capital Management Boston, Massachusetts $1.88T AUM 44.46% 1-Year Est. Return
ACM
ADAR1 Capital Management Austin, Texas $2.19B AUM 374.99% 1-Year Est. Return
CCC
Cable Car Capital San Francisco, California $4.66B AUM 77.16% 1-Year Est. Return
Citadel Advisors
Citadel Advisors Miami, Florida $875B AUM 40.91% 1-Year Est. Return
SC
Stempoint Capital New York $581M AUM 373.68% 1-Year Est. Return
EP
Eversept Partners New York $1.93B AUM 160.8% 1-Year Est. Return

State Street's SPRB Position: Q2 2026 in Review

State Street increased its Spruce Biosciences (SPRB) stake by 834% in Q2 2026, buying an estimated $2.52M and bringing the position to 50,450 shares worth $2.72M. The position accounts for ﹤0.01% of the portfolio, ranked #3229.

State Street first reported a position in SPRB in Q4 2020 and has held it in 21 quarters since. 57 funds tracked by Wall St. Rank hold SPRB as of Q2 2026.

  • State Street held 50,450 shares of Spruce Biosciences worth $2.72M as of Q2 2026.
  • State Street bought 45,050 Spruce Biosciences shares in Q2 2026, an estimated $2.52M.
  • Spruce Biosciences made up ﹤0.01% of State Street's portfolio in Q2 2026, its #3229 holding.
  • State Street first reported a position in Spruce Biosciences in Q4 2020 and has held it in 21 quarters since.
  • 57 funds tracked by Wall St. Rank held Spruce Biosciences as of Q2 2026.

Based on State Street's 13F filing for Q2 2026, filed 7 Aug 2026.