SPRB

Spruce Biosciences, Inc. Common Stock
SPRB

Overview Fund Activity
Delisted

SPRB was delisted on the 28th of April, 2025.

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30 hedge funds and large institutions have $4.69M invested in Spruce Biosciences, Inc. Common Stock in 2024 Q4 according to their latest regulatory filings, with 6 funds opening new positions, 5 increasing their positions, 10 reducing their positions, and 4 closing their positions.

Holders
30
Holders Change
+1
Holders Change %
+3.45%
% of All Funds
0.4%
Holding in Top 10
–
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-100%
% of All Funds
–
New
6
Increased
5
Reduced
10
Closed
4
Calls
$9K
Puts
–
Net Calls
+$9K
Net Calls Change
+$1K

Top Buyers

1
IC
1
Ikarian Capital
Texas
$420K
2
BFM
2
Boothbay Fund Management
New York
$121K
3
UBS Group
3
UBS Group
Switzerland
$36.1K
4
Susquehanna International Group
4
Susquehanna International Group
Pennsylvania
$24.8K
5
HF
5
HRT Financial
New York
$15K

Top Sellers

1
AC
1
Almitas Capital
California
$0
2
Acadian Asset Management
2
Acadian Asset Management
Massachusetts
$437K
3
Renaissance Technologies
3
Renaissance Technologies
New York
$170K
4
Citadel Advisors
4
Citadel Advisors
Florida
$0
5
SCV
5
Sands Capital Ventures
Virginia
$301K
Name Market Value Shares Shares
Change 		Shares
Change %
CG
1
Carlyle Group
District of Columbia
$1.22M 2,896,518 – –
RSCM
2
Rock Springs Capital Management
Maryland
$1.1M 2,609,125 – –
Acadian Asset Management
3
Acadian Asset Management
Massachusetts
$437K 1,045,828 -213,323 -17%
IC
4
Ikarian Capital
Texas
$420K 1,000,000 +1,000,000 New
Vanguard Group
5
Vanguard Group
Pennsylvania
$354K 843,844 – –
SCV
6
Sands Capital Ventures
Virginia
$301K 715,817 -71,190 -9%
Renaissance Technologies
7
Renaissance Technologies
New York
$170K 405,900 -203,800 -33%
ACM
8
ADAR1 Capital Management
Texas
$170K 403,716 – –
BFM
9
Boothbay Fund Management
New York
$121K 288,800 +288,800 New
Geode Capital Management
10
Geode Capital Management
Massachusetts
$115K 273,785 +11,837 +5%
BlackRock
11
BlackRock
New York
$52.4K 124,734 – –
UBS Group
12
UBS Group
Switzerland
$36.1K 86,045 +86,032 +661,785%
Northern Trust
13
Northern Trust
Illinois
$33.7K 80,308 +5,381 +7%
LPC
14
Lion Point Capital
New York
$31.5K 75,000 – –
State Street
15
State Street
Massachusetts
$25.5K 60,700 -3,700 -6%
Susquehanna International Group
16
Susquehanna International Group
Pennsylvania
$24.8K 58,984 +58,984 New
SC
17
Shay Capital
New York
$16K 38,119 – –
HF
18
HRT Financial
New York
$15K 37,838 +37,838 New
XT
19
XTX Topco
Cayman Islands
$14.9K 35,549 +16,415 +86%
BCM
20
Bridgeway Capital Management
Texas
$14.7K 34,900 -5,100 -13%
Two Sigma Investments
21
Two Sigma Investments
New York
$8.66K 20,616 -2,752 -12%
Two Sigma Advisers
22
Two Sigma Advisers
New York
$5.8K 13,800 -13,300 -49%
TRCT
23
Tower Research Capital (TRC)
New York
$2K 4,761 +111 +2%
Simplex Trading
24
Simplex Trading
Illinois
$2K 4,857 +4,857 New
Morgan Stanley
25
Morgan Stanley
New York
$896 2,133 – –
1
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