SPRB

Spruce Biosciences, Inc. Common Stock
SPRB

Overview Fund Activity
Delisted

SPRB was delisted on the 28th of April, 2025.

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40 hedge funds and large institutions have $313M invested in Spruce Biosciences, Inc. Common Stock in 2021 Q1 according to their latest regulatory filings, with 1 funds opening new positions, 15 increasing their positions, 12 reducing their positions, and 6 closing their positions.

Holders
40
Holders Change
-5
Holders Change %
-11.11%
% of All Funds
0.7%
Holding in Top 10
4
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-20%
% of All Funds
0.07%
New
1
Increased
15
Reduced
12
Closed
6
Calls
–
Puts
–
Net Calls
–
Net Calls Change
–

Top Buyers

1
SCM
1
Sio Capital Management
New York
$13.5M
2
Morgan Stanley
2
Morgan Stanley
New York
$569K
3
BlackRock
3
BlackRock
New York
$5.73M
4
Goldman Sachs
4
Goldman Sachs
New York
$207K
5
Bank of America
5
Bank of America
North Carolina
$214K

Top Sellers

1
AIC
1
AWM Investment Company
New York
$0
2
RSCM
2
Rock Springs Capital Management
Maryland
$26.2M
3
Millennium Management
3
Millennium Management
New York
$1.21M
4
PHS
4
PFM Health Sciences
California
$8.13M
5
ZP
5
Zimmer Partners
New York
$0
Name Market Value Shares Shares
Change 		Shares
Change %
NHAS
1
Novo Holdings A/S
Denmark
$82.8M 4,989,336 – –
OFM
2
Omega Fund Management
Massachusetts
$35.9M 2,161,022 – –
RVM
3
RiverVest Venture Management
Missouri
$35.7M 2,148,281 – –
Citadel Advisors
4
Citadel Advisors
Florida
$28.3M 1,702,805 +1,018 +0.1%
RSCM
5
Rock Springs Capital Management
Maryland
$26.2M 1,579,301 -51,699 -3%
ACM
6
Aisling Capital Management
New York
$20M 1,205,511 – –
Fidelity Investments
7
Fidelity Investments
Massachusetts
$19.8M 1,195,090 +817 +0.1%
SCM
8
Sio Capital Management
New York
$13.5M 812,884 +176,231 +28%
Sands Capital Management
9
Sands Capital Management
Virginia
$13.1M 787,007 – –
PHS
10
PFM Health Sciences
California
$8.13M 489,631 -39,680 -7%
BlackRock
11
BlackRock
New York
$5.73M 345,306 +13,274 +4%
Adage Capital Partners
12
Adage Capital Partners
Massachusetts
$4.82M 290,511 – –
Vanguard Group
13
Vanguard Group
Pennsylvania
$3.13M 188,517 +4,459 +2%
JPMorgan Chase & Co
14
JPMorgan Chase & Co
New York
$2.99M 180,023 -8,804 -5%
ACH
15
ArrowMark Colorado Holdings
Colorado
$2.13M 128,000 – –
Geode Capital Management
16
Geode Capital Management
Massachusetts
$1.82M 109,547 -7,971 -7%
GPCM
17
Granite Point Capital Management
Massachusetts
$1.66M 100,000 – –
State Street
18
State Street
Massachusetts
$1.57M 94,749 +6,771 +8%
Northern Trust
19
Northern Trust
Illinois
$1.26M 76,144 -3,060 -4%
Millennium Management
20
Millennium Management
New York
$1.21M 73,081 -51,627 -41%
Charles Schwab
21
Charles Schwab
California
$733K 44,138 +3,786 +9%
Morgan Stanley
22
Morgan Stanley
New York
$569K 34,292 +28,963 +543%
CS
23
Credit Suisse
Switzerland
$397K 23,899 -1,814 -7%
LCM
24
Laurion Capital Management
New York
$332K 20,000 – –
Bank of New York Mellon
25
Bank of New York Mellon
New York
$318K 19,180 +5,688 +42%
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