SPRB

Spruce Biosciences, Inc. Common Stock
SPRB

Overview Fund Activity
Delisted

SPRB was delisted on the 28th of April, 2025.

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44 hedge funds and large institutions have $74.5M invested in Spruce Biosciences, Inc. Common Stock in 2023 Q1 according to their latest regulatory filings, with 16 funds opening new positions, 11 increasing their positions, 10 reducing their positions, and 2 closing their positions.

Holders
44
Holders Change
+13
Holders Change %
+41.94%
% of All Funds
0.7%
Holding in Top 10
2
Holding in Top 10 Change
+1
Holding in Top 10 Change %
+100%
% of All Funds
0.03%
New
16
Increased
11
Reduced
10
Closed
2
Calls
–
Puts
–
Net Calls
–
Net Calls Change
–

Top Buyers

1
AC
1
Armistice Capital
New York
$8.68M
2
CG
2
Carlyle Group
District of Columbia
$6.4M
3
5VM
3
5AM Venture Management
California
$5.22M
4
NHAS
4
Novo Holdings A/S
Denmark
$14.9M
5
RSCM
5
Rock Springs Capital Management
Maryland
$6.03M

Top Sellers

1
LGM
1
Logos Global Management
California
$0
2
BCM
2
BML Capital Management
Indiana
$0
3
Citadel Advisors
3
Citadel Advisors
Florida
$3.75M
4
PFMU
4
Privium Fund Management (UK)
United Kingdom
$52.5K
5
MAM
5
Marquette Asset Management
Minnesota
$123K
Name Market Value Shares Shares
Change 		Shares
Change %
NHAS
1
Novo Holdings A/S
Denmark
$14.9M 6,722,336 +2,208,000 +49%
AC
2
Armistice Capital
New York
$8.68M 3,928,000 +3,928,000 New
RVM
3
RiverVest Venture Management
Missouri
$6.49M 2,936,281 +788,000 +37%
CG
4
Carlyle Group
District of Columbia
$6.4M 2,896,518 +2,896,518 New
RSCM
5
Rock Springs Capital Management
Maryland
$6.03M 2,728,125 +1,105,436 +68%
5VM
6
5AM Venture Management
California
$5.22M 2,364,000 +2,364,000 New
OFM
7
Omega Fund Management
Massachusetts
$4.78M 2,161,022 – –
Citadel Advisors
8
Citadel Advisors
Florida
$3.75M 1,698,618 -48,773 -3%
ACM
9
Aisling Capital Management
New York
$2.66M 1,205,511 – –
ACM
10
AIGH Capital Management
Maryland
$2.37M 1,104,000 +1,104,000 New
Alyeska Investment Group
11
Alyeska Investment Group
Illinois
$2.21M 1,000,000 +1,000,000 New
Verition Fund Management
12
Verition Fund Management
Connecticut
$2.13M 961,899 +961,899 New
SCV
13
Sands Capital Ventures
Virginia
$1.74M 787,007 – –
Millennium Management
14
Millennium Management
New York
$1.35M 608,845 +461,349 +313%
CH
15
CVI Holdings
Delaware
$1.04M 472,000 +472,000 New
DCM
16
DAFNA Capital Management
California
$690K 312,000 +312,000 New
WVP
17
Worth Venture Partners
New Jersey
$581K 270,624 +270,624 New
Vanguard Group
18
Vanguard Group
Pennsylvania
$545K 246,578 +121,465 +97%
Goldman Sachs
19
Goldman Sachs
New York
$404K 182,656 +182,656 New
Two Sigma Investments
20
Two Sigma Investments
New York
$361K 163,165 +163,165 New
Renaissance Technologies
21
Renaissance Technologies
New York
$354K 160,100 +21,683 +16%
BlackRock
22
BlackRock
New York
$334K 151,313 +894 +0.6%
Royal Bank of Canada
23
Royal Bank of Canada
Ontario, Canada
$208K 93,920 +93,920 New
State Street
24
State Street
Massachusetts
$206K 93,100 – –
Bank of New York Mellon
25
Bank of New York Mellon
New York
$203K 92,077 – –
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