SPRB

Spruce Biosciences, Inc. Common Stock
SPRB

Overview Fund Activity
Delisted

SPRB was delisted on the 28th of April, 2025.

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29 hedge funds and large institutions have $6.4M invested in Spruce Biosciences, Inc. Common Stock in 2024 Q3 according to their latest regulatory filings, with 0 funds opening new positions, 6 increasing their positions, 11 reducing their positions, and 8 closing their positions.

Holders
29
Holders Change
-8
Holders Change %
-21.62%
% of All Funds
0.42%
Holding in Top 10
1
Holding in Top 10 Change
–
Holding in Top 10 Change %
–
% of All Funds
0.01%
New
–
Increased
6
Reduced
11
Closed
8
Calls
$9K
Puts
$1K
Net Calls
+$8K
Net Calls Change
-$27K

Top Buyers

1
Renaissance Technologies
1
Renaissance Technologies
New York
$290K
2
Geode Capital Management
2
Geode Capital Management
Massachusetts
$124K
3
ACM
3
ADAR1 Capital Management
Texas
$192K
4
SC
4
Shay Capital
New York
$18.1K
5
Royal Bank of Canada
5
Royal Bank of Canada
Ontario, Canada
$2K

Top Sellers

1
RA
1
Rosalind Advisors
Ontario, Canada
$0
2
ACM
2
Altium Capital Management
New York
$0
3
ECM
3
ExodusPoint Capital Management
New York
$0
4
6CM
4
683 Capital Management
New York
$0
5
UBS Group
5
UBS Group
Switzerland
$6
Name Market Value Shares Shares
Change 		Shares
Change %
RVM
1
RiverVest Venture Management
Missouri
$1.39M 2,936,281 – –
CG
2
Carlyle Group
District of Columbia
$1.32M 2,896,518 – –
RSCM
3
Rock Springs Capital Management
Maryland
$1.24M 2,609,125 – –
Acadian Asset Management
4
Acadian Asset Management
Massachusetts
$597K 1,259,151 -108,846 -8%
Vanguard Group
5
Vanguard Group
Pennsylvania
$401K 843,844 -19,531 -2%
SCV
6
Sands Capital Ventures
Virginia
$370K 787,007 – –
Renaissance Technologies
7
Renaissance Technologies
New York
$290K 609,700 +243,600 +67%
ACM
8
ADAR1 Capital Management
Texas
$192K 403,716 +48,500 +14%
AC
9
Almitas Capital
California
$188K 396,506 – –
Geode Capital Management
10
Geode Capital Management
Massachusetts
$124K 261,948 +57,946 +28%
BlackRock
11
BlackRock
New York
$59.2K 124,734 – –
Citadel Advisors
12
Citadel Advisors
Florida
$36.6K 77,053 -7,662 -9%
LPC
13
Lion Point Capital
New York
$35.6K 75,000 – –
Northern Trust
14
Northern Trust
Illinois
$35.6K 74,927 – –
State Street
15
State Street
Massachusetts
$30.6K 64,400 – –
BCM
16
Bridgeway Capital Management
Texas
$19K 40,000 -45,000 -53%
SC
17
Shay Capital
New York
$18.1K 38,119 +24,947 +189%
Two Sigma Advisers
18
Two Sigma Advisers
New York
$12.9K 27,100 -18,600 -41%
Two Sigma Investments
19
Two Sigma Investments
New York
$11.1K 23,368 -5,216 -18%
XT
20
XTX Topco
Cayman Islands
$9.09K 19,134 -8,051 -30%
Jane Street
21
Jane Street
New York
$7.44K 15,658 -15,190 -49%
TRCT
22
Tower Research Capital (TRC)
New York
$2.21K 4,650 -28,437 -86%
Royal Bank of Canada
23
Royal Bank of Canada
Ontario, Canada
$2K 3,733 +3,517 +1,628%
Group One Trading
24
Group One Trading
Illinois
$1.82K 3,839 – –
Morgan Stanley
25
Morgan Stanley
New York
$1.01K 2,133 – –
1
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