Regulus Therapeutics

RGLS

Market cap $565M

Delisted

RGLS was delisted on the 24th of June, 2025.

25 hedge funds and large institutions have $15M invested in Regulus Therapeutics in 2023 Q2 according to their latest regulatory filings, with 1 funds opening new positions, 12 increasing their positions, 1 reducing their positions, and 2 closing their positions.

New

Increased

Maintained

Reduced

Closed

1,100% more repeat investments, than reductions

Existing positions increased: 12 | Existing positions reduced: 1

120% more capital invested

Capital invested by funds: $6.8M → $15M (+$8.15M)

4.46% more ownership

Funds ownership: 47.77% → 52.23% (+4.5%)

4% less funds holding

Funds holding: 26 → 25 (-1)

50% less first-time investments, than exits

New positions opened: 1 | Existing positions closed: 2

100% less funds holding in top 10

Funds holding in top 10: 1 → 0 (-1)

Holders

Holders Change

-1

Holders Change %

-3.85%

% of All Funds

0.39%

Holding in Top 10

–

Holding in Top 10 Change

-1

Holding in Top 10 Change %

-100%

% of All Funds

–

New

Increased

Reduced

Closed

Calls

$580K

Puts

–

Net Calls

+$580K

Net Calls Change

+$251K

Top Buyers

1	Federated Hermes Pittsburgh, Pennsylvania	+$1.29M
2	DCM DAFNA Capital Management Los Angeles, California	+$740K
3	NMC NEA Management Company Timonium, Maryland	+$667K
4	PCM Prelude Capital Management New York	+$54.2K
5	Geode Capital Management Boston, Massachusetts	+$50.7K

Top Sellers

1	Jane Street New York	-$15.4K
2	TRCT Tower Research Capital (TRC) New York	-$5.33K
3	Group One Trading Chicago, Illinois	-$655

#	Name	Holding	Trade Value	Shares Change	Change in Stake
1	1 Federated Hermes Pittsburgh, Pennsylvania	$5.7M	+$1.29M	+970,752	+33%
2	2 Fidelity Investments Boston, Massachusetts	$3.24M	+$15.5K	+11,600	+0.5%
3	NMC 3 NEA Management Company Timonium, Maryland	$2.86M	+$667K	+500,465	+35%
4	DCM 4 DAFNA Capital Management Los Angeles, California	$1.63M	+$740K	+555,494	+100%
5	5 Vanguard Group Malvern, Pennsylvania	$416K	–	–	–
6	6 Victory Capital Management San Antonio, Texas	$326K	–	–	–
7	SCM 7 Sarissa Capital Management Greenwich, Connecticut	$272K	–	–	–
8	8 Geode Capital Management Boston, Massachusetts	$166K	+$50.7K	+38,049	+51%
9	9 Renaissance Technologies New York	$68K	+$9.72K	+7,300	+19%
10	10 State Street Boston, Massachusetts	$61.3K	–	–	–
11	PCM 11 Prelude Capital Management New York	$59.8K	+$54.2K	+40,660	New
12	12 Citadel Advisors Miami, Florida	$40.9K	+$29.3K	+22,019	+381%
13	13 LPL Financial San Diego, California	$27.2K	+$6.66K	+5,000	+37%
14	14 Northern Trust Chicago, Illinois	$26.4K	–	–	–
15	15 Commonwealth Equity Services Waltham, Massachusetts	$26K	–	–	–
16	GC 16 Grimes & Company Westborough, Massachusetts	$15.2K	–	–	–
17	TRCT 17 Tower Research Capital (TRC) New York	$11.5K	-$5.33K	-4,002	-34%
18	18 UBS Group Zurich, Switzerland	$5.31K	+$2.5K	+1,874	+108%
19	CB 19 Community Bank Dewitt, New York	$1.01K	–	–	–
20	20 BlackRock New York	$908	–	–	–
21	21 Barclays London, United Kingdom	$331	+$293	+220	+4,400%
22	22 Wells Fargo San Francisco, California	$187	+$28	+21	+20%
23	23 Osaic Holdings Scottsdale, Arizona	$73	–	–	–
24	24 Jane Street New York	–	-$15.4K	-18,189	Closed
25	25 Group One Trading Chicago, Illinois	–	-$655	-492	Closed