RGLS

Regulus Therapeutics
RGLS

Overview Fund Activity
Delisted

RGLS was delisted on the 24th of June, 2025.

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31 hedge funds and large institutions have $24.8M invested in Regulus Therapeutics in 2020 Q4 according to their latest regulatory filings, with 11 funds opening new positions, 8 increasing their positions, 3 reducing their positions, and 7 closing their positions.

Holders
31
Holders Change
+4
Holders Change %
+14.81%
% of All Funds
0.55%
Holding in Top 10
1
Holding in Top 10 Change
–
Holding in Top 10 Change %
–
% of All Funds
0.02%
New
11
Increased
8
Reduced
3
Closed
7
Calls
$92K
Puts
$34K
Net Calls
+$58K
Net Calls Change
+$52K

Top Buyers

1
NMC
1
NEA Management Company
Maryland
$8.71M
2
Point72 Asset Management
2
Point72 Asset Management
Connecticut
$4.29M
3
CH
3
CVI Holdings
Delaware
$2.17M
4
Victory Capital Management
4
Victory Capital Management
Texas
$675K
5
Renaissance Technologies
5
Renaissance Technologies
New York
$606K

Top Sellers

1
Citadel Advisors
1
Citadel Advisors
Florida
$0
2
WS
2
Wedbush Securities
California
$0
3
BlackRock
3
BlackRock
New York
$68K
4
Simplex Trading
4
Simplex Trading
Illinois
$0
5
Wells Fargo
5
Wells Fargo
California
$10K
Name Market Value Shares Shares
Change 		Shares
Change %
NMC
1
NEA Management Company
Maryland
$8.71M 6,451,056 +4,398,601 +214%
BI
2
BVF Inc
California
$4.56M 3,376,207 +158,727 +5%
Point72 Asset Management
3
Point72 Asset Management
Connecticut
$4.29M 3,215,436 +3,215,436 New
SCM
4
Sarissa Capital Management
Connecticut
$2.5M 1,851,851 – –
CH
5
CVI Holdings
Delaware
$2.17M 1,607,720 +1,607,720 New
Victory Capital Management
6
Victory Capital Management
Texas
$675K 499,989 +499,989 New
Renaissance Technologies
7
Renaissance Technologies
New York
$606K 449,200 +449,200 New
Vanguard Group
8
Vanguard Group
Pennsylvania
$522K 386,659 +281,210 +267%
TRCT
9
Tower Research Capital (TRC)
New York
$163K 120,986 +94,279 +353%
Geode Capital Management
10
Geode Capital Management
Massachusetts
$86K 64,347 – –
Goldman Sachs
11
Goldman Sachs
New York
$76K 56,336 +56,336 New
GC
12
Grimes & Company
Massachusetts
$74K 54,511 +30,513 +127%
GFS
13
GYL Financial Synergies
Connecticut
$69K 51,376 +51,376 New
BlackRock
14
BlackRock
New York
$68K 49,788 -15,023 -23%
Northern Trust
15
Northern Trust
Illinois
$53K 39,431 -3,271 -8%
Two Sigma Investments
16
Two Sigma Investments
New York
$40K 29,716 +29,716 New
MIG
17
McGuire Investment Group
Rhode Island
$32K 24,000 – –
AWM
18
Altus Wealth Management
Kentucky
$19K 13,805 +13,805 New
DY
19
Dowling & Yahnke
California
$16K 12,000 – –
William Blair & Company
20
William Blair & Company
Illinois
$15K 11,200 – –
Squarepoint
21
Squarepoint
New York
$14K 10,129 +10,129 New
Group One Trading
22
Group One Trading
Illinois
$12K 8,900 +7,700 +642%
Wells Fargo
23
Wells Fargo
California
$10K 7,325 -9,480 -56%
Royal Bank of Canada
24
Royal Bank of Canada
Ontario, Canada
$9K 7,063 – –
Morgan Stanley
25
Morgan Stanley
New York
$8K 5,630 +4,900 +671%
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