RGLS

Regulus Therapeutics
RGLS

Overview Fund Activity
Delisted

RGLS was delisted on the 24th of June, 2025.

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70 hedge funds and large institutions have $89.1M invested in Regulus Therapeutics in 2024 Q3 according to their latest regulatory filings, with 16 funds opening new positions, 20 increasing their positions, 12 reducing their positions, and 8 closing their positions.

Holders
70
Holders Change
+7
Holders Change %
+11.11%
% of All Funds
1.01%
Holding in Top 10
1
Holding in Top 10 Change
–
Holding in Top 10 Change %
–
% of All Funds
0.01%
New
16
Increased
20
Reduced
12
Closed
8
Calls
$195K
Puts
$87K
Net Calls
+$108K
Net Calls Change
-$102K

Top Buyers

1
T. Rowe Price Associates
1
T. Rowe Price Associates
Maryland
$3.38M
2
Point72 Asset Management
2
Point72 Asset Management
Connecticut
$1.4M
3
Northern Trust
3
Northern Trust
Illinois
$781K
4
TD Asset Management
4
TD Asset Management
Ontario, Canada
$486K
5
Manulife (Manufacturers Life Insurance)
5
Manulife (Manufacturers Life Insurance)
Ontario, Canada
$204K

Top Sellers

1
RCM
1
RA Capital Management
Massachusetts
$1.2M
2
Fidelity Investments
2
Fidelity Investments
Massachusetts
$515K
3
OM
3
Opaleye Management
Massachusetts
$840K
4
ECM
4
ExodusPoint Capital Management
New York
$0
5
Hudson Bay Capital Management
5
Hudson Bay Capital Management
Connecticut
$0
Name Market Value Shares Shares
Change 		Shares
Change %
Federated Hermes
1
Federated Hermes
Pennsylvania
$20.2M 12,852,654 – –
NMC
2
NEA Management Company
Maryland
$10.2M 6,467,802 – –
VC
3
Vivo Capital
California
$7.85M 5,000,000 – –
OCA
4
Octagon Capital Advisors
New York
$6.69M 4,263,701 – –
Vanguard Group
5
Vanguard Group
Pennsylvania
$6.42M 4,088,760 +37,897 +0.9%
BlackRock
6
BlackRock
New York
$6.41M 4,081,038 +112,181 +3%
DTC
7
Deep Track Capital
Connecticut
$5.12M 3,262,564 – –
T. Rowe Price Associates
8
T. Rowe Price Associates
Maryland
$3.38M 2,151,071 +2,130,678 +10,448%
Adage Capital Partners
9
Adage Capital Partners
Massachusetts
$3.14M 2,000,000 – –
Millennium Management
10
Millennium Management
New York
$2.03M 1,291,415 +75,834 +6%
Geode Capital Management
11
Geode Capital Management
Massachusetts
$2.01M 1,280,567 -52,942 -4%
Alyeska Investment Group
12
Alyeska Investment Group
Illinois
$1.63M 1,037,500 +100,000 +11%
State Street
13
State Street
Massachusetts
$1.57M 1,000,998 +33,496 +3%
WP
14
Woodline Partners
California
$1.49M 948,702 +1,017 +0.1%
DCM
15
DAFNA Capital Management
California
$1.41M 895,200 – –
Point72 Asset Management
16
Point72 Asset Management
Connecticut
$1.4M 893,762 +893,762 New
RCM
17
RA Capital Management
Massachusetts
$1.2M 766,834 -5,483,166 -88%
OM
18
Opaleye Management
Massachusetts
$840K 535,000 -940,000 -64%
Northern Trust
19
Northern Trust
Illinois
$781K 497,304 +324,554 +188%
Victory Capital Management
20
Victory Capital Management
Texas
$626K 398,866 +37,480 +10%
Fidelity Investments
21
Fidelity Investments
Massachusetts
$515K 328,157 -1,694,443 -84%
TD Asset Management
22
TD Asset Management
Ontario, Canada
$486K 302,000 +302,000 New
SCM
23
Sarissa Capital Management
Connecticut
$291K 185,183 – –
Goldman Sachs
24
Goldman Sachs
New York
$281K 179,005 +40,540 +29%
Charles Schwab
25
Charles Schwab
California
$281K 178,879 – –
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