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RGLS

Regulus Therapeutics

Delisted

RGLS was delisted on the 24th of June, 2025.

103 hedge funds and large institutions have $299M invested in Regulus Therapeutics in 2015 Q4 according to their latest regulatory filings, with 20 funds opening new positions, 34 increasing their positions, 29 reducing their positions, and 8 closing their positions.

New
Increased
Maintained
Reduced
Closed

1,559% more call options, than puts

Call options by funds: $12.7M | Put options by funds: $768K

150% more first-time investments, than exits

New positions opened: 20 | Existing positions closed: 8

50% more funds holding in top 10

Funds holding in top 10: 23 (+1)

32% more capital invested

Capital invested by funds: $226M → $299M (+$72.7M)

17% more repeat investments, than reductions

Existing positions increased: 34 | Existing positions reduced: 29

12% more funds holding

Funds holding: 92103 (+11)

Holders
103
Holders Change
+11
Holders Change %
+11.96%
% of All Funds
2.7%
Holding in Top 10
3
Holding in Top 10 Change
+1
Holding in Top 10 Change %
+50%
% of All Funds
0.08%
New
20
Increased
34
Reduced
29
Closed
8
Calls
$12.7M
Puts
$768K
Net Calls
+$12M
Net Calls Change
+$4.59M
Name Holding Trade Value Shares
Change
Change in
Stake
Fidelity Investments
1
Fidelity Investments
Massachusetts
$68.5M +$530K +529 +0.8%
Wellington Management Group
2
Wellington Management Group
Massachusetts
$36.7M -$35.1K -35 -0.1%
RCM
3
RA Capital Management
Massachusetts
$30.4M -$4.65M -4,641 -14%
UBS AM
4
UBS AM
Illinois
$23.2M +$3.74M +3,733 +20%
Capital World Investors
5
Capital World Investors
California
$17.6M
FCMI
6
Foresite Capital Management II
California
$15.3M +$3.01K +3 +0%
BFA
7
BlackRock Fund Advisors
California
$12M -$906K -904 -7%
Vanguard Group
8
Vanguard Group
Pennsylvania
$9.63M +$678K +676 +8%
Axa
9
Axa
France
$7.92M -$159K -159 -2%
Goldman Sachs
10
Goldman Sachs
New York
$6.5M +$545K +544 +10%
FCMI
11
Foresite Capital Management III
California
$6.27M +$6.01M +5,992 New
BIT
12
BlackRock Institutional Trust
California
$6.1M +$158K +158 +3%
CPIM
13
Columbia Partners Investment Management
Virginia
$5.34M +$3.54M +3,535 +226%
State Street
14
State Street
Massachusetts
$3.01M +$167K +167 +6%
A
15
Abingworth
United Kingdom
$2.85M
Northern Trust
16
Northern Trust
Illinois
$2.81M +$105K +105 +4%
Wells Fargo
17
Wells Fargo
California
$2.38M +$72.2K +72 +3%
OAM
18
Oxford Asset Management
United Kingdom
$2.33M +$2.18M +2,173 New
California Public Employees Retirement System
19
California Public Employees Retirement System
California
$1.99M
SM
20
Sabby Management
Florida
$1.83M -$1.22M -1,221 -41%
Royal Bank of Canada
21
Royal Bank of Canada
Ontario, Canada
$1.83M +$120K +120 +7%
RPAM
22
Rhenman & Partners Asset Management
Sweden
$1.74M
SDIC
23
South Dakota Investment Council
South Dakota
$1.64M -$440K -439 -22%
Geode Capital Management
24
Geode Capital Management
Massachusetts
$1.59M +$21.1K +21 +1%
EAM
25
Eventide Asset Management
Massachusetts
$1.4M

RGLS Hedge Fund Activity: Q4 2015 in Review

103 of the 3,812 institutional investors tracked by Wall St. Rank reported a position in Regulus Therapeutics (RGLS) for Q4 2015, worth a combined $299M — up 32% from $226M a quarter earlier.

Buyers outnumbered sellers: 20 funds opened new RGLS positions and 8 closed out — a net gain of 12 holders — while 34 added to existing stakes and 29 trimmed.

The largest buyer was UBS AM, adding an estimated $3.74M. The largest seller was Cormorant Asset Management, cutting an estimated $7.23M.

  • 103 institutional investors held Regulus Therapeutics (RGLS) as of Q4 2015, up from 92 in Q3 2015.
  • Funds reported $299M of Regulus Therapeutics stock for Q4 2015, up 32% quarter-over-quarter.
  • 20 funds opened new Regulus Therapeutics positions in Q4 2015 and 8 closed out, a net change of +12 holders.
  • The largest Regulus Therapeutics buyer in Q4 2015 was UBS AM, an estimated $3.74M added.
  • The largest Regulus Therapeutics seller in Q4 2015 was Cormorant Asset Management, an estimated $7.23M sold.

Based on aggregated 13F filings for Q4 2015.