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RGLS

Regulus Therapeutics

Delisted

RGLS was delisted on the 24th of June, 2025.

69 hedge funds and large institutions have $84.5M invested in Regulus Therapeutics in 2024 Q4 according to their latest regulatory filings, with 11 funds opening new positions, 22 increasing their positions, 16 reducing their positions, and 11 closing their positions.

New
Increased
Maintained
Reduced
Closed

245% more call options, than puts

Call options by funds: $38K | Put options by funds: $11K

38% more repeat investments, than reductions

Existing positions increased: 22 | Existing positions reduced: 16

0% more first-time investments, than exits

New positions opened: 11 | Existing positions closed: 11

1% less funds holding

Funds holding: 7069 (-1)

4.96% less ownership

Funds ownership: 86.65%81.69% (-5%)

5% less capital invested

Capital invested by funds: $89.1M → $84.5M (-$4.54M)

100% less funds holding in top 10

Funds holding in top 10: 10 (-1)

Holders
69
Holders Change
-1
Holders Change %
-1.43%
% of All Funds
0.91%
Holding in Top 10
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-100%
% of All Funds
New
11
Increased
22
Reduced
16
Closed
11
Calls
$38K
Puts
$11K
Net Calls
+$27K
Net Calls Change
-$81K
Name Holding Trade Value Shares
Change
Change in
Stake
Federated Hermes
1
Federated Hermes
Pennsylvania
$20.3M
NMC
2
NEA Management Company
Maryland
$10.2M
VC
3
Vivo Capital
California
$7.9M
OCA
4
Octagon Capital Advisors
New York
$7.66M +$899K +585,101 +14%
BlackRock
5
BlackRock
New York
$6.69M +$239K +155,531 +4%
Vanguard Group
6
Vanguard Group
Pennsylvania
$6.27M -$187K -121,669 -3%
DTC
7
Deep Track Capital
Connecticut
$5.15M
Millennium Management
8
Millennium Management
New York
$3.46M +$1.38M +900,743 +70%
Adage Capital Partners
9
Adage Capital Partners
Massachusetts
$3.16M
Geode Capital Management
10
Geode Capital Management
Massachusetts
$2.02M -$1.9K -1,236 -0.1%
State Street
11
State Street
Massachusetts
$1.67M +$85.1K +55,413 +6%
Alyeska Investment Group
12
Alyeska Investment Group
Illinois
$1.64M
Point72 Asset Management
13
Point72 Asset Management
Connecticut
$1.41M +$2.1K +1,366 +0.2%
DCM
14
DAFNA Capital Management
California
$1.38M -$30.7K -20,000 -2%
Northern Trust
15
Northern Trust
Illinois
$722K -$61.6K -40,071 -8%
Victory Capital Management
16
Victory Capital Management
Texas
$616K -$13.8K -8,980 -2%
RCM
17
RA Capital Management
Massachusetts
$532K -$661K -429,991 -56%
Goldman Sachs
18
Goldman Sachs
New York
$336K +$51.3K +33,374 +19%
JP Morgan Chase
19
JP Morgan Chase
New York
$301K +$171K +111,485 +141%
Charles Schwab
20
Charles Schwab
California
$283K
Citadel Advisors
21
Citadel Advisors
Florida
$246K +$239K +155,526 +486,019%
Bank of New York Mellon
22
Bank of New York Mellon
New York
$236K -$2 -1 -0%
Morgan Stanley
23
Morgan Stanley
New York
$221K -$43.4K -28,282 -17%
Renaissance Technologies
24
Renaissance Technologies
New York
$185K +$30.6K +19,900 +20%
TWP
25
Tyche Wealth Partners
Texas
$168K

RGLS Hedge Fund Activity: Q4 2024 in Review

69 of the 7,592 institutional investors tracked by Wall St. Rank reported a position in Regulus Therapeutics (RGLS) for Q4 2024, worth a combined $84.5M — down 5.1% from $89.1M a quarter earlier.

Fund positioning in RGLS was balanced in Q4 2024: 11 funds opened new positions, 11 closed out, 22 added to existing stakes and 16 trimmed.

The largest buyer was Millennium Management, adding an estimated $1.38M. The largest seller was T. Rowe Price Associates, cutting an estimated $3.26M.

  • 69 institutional investors held Regulus Therapeutics (RGLS) as of Q4 2024, down from 70 in Q3 2024.
  • Funds reported $84.5M of Regulus Therapeutics stock for Q4 2024, down 5.1% quarter-over-quarter.
  • 11 funds opened new Regulus Therapeutics positions in Q4 2024 and 11 closed out, a net change of 0 holders.
  • The largest Regulus Therapeutics buyer in Q4 2024 was Millennium Management, an estimated $1.38M added.
  • The largest Regulus Therapeutics seller in Q4 2024 was T. Rowe Price Associates, an estimated $3.26M sold.

Based on aggregated 13F filings for Q4 2024.