RGLS

Regulus Therapeutics
RGLS

Overview Fund Activity
Delisted

RGLS was delisted on the 24th of June, 2025.

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63 hedge funds and large institutions have $109M invested in Regulus Therapeutics in 2024 Q2 according to their latest regulatory filings, with 28 funds opening new positions, 13 increasing their positions, 14 reducing their positions, and 10 closing their positions.

Holders
63
Holders Change
+18
Holders Change %
+40%
% of All Funds
0.92%
Holding in Top 10
1
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-50%
% of All Funds
0.01%
New
28
Increased
13
Reduced
14
Closed
10
Calls
$329K
Puts
$119K
Net Calls
+$210K
Net Calls Change
-$739K

Top Buyers

1
OCA
1
Octagon Capital Advisors
New York
$7.61M
2
BlackRock
2
BlackRock
New York
$7.08M
3
Vanguard Group
3
Vanguard Group
Pennsylvania
$7.23M
4
OM
4
Opaleye Management
Massachusetts
$2.63M
5
Geode Capital Management
5
Geode Capital Management
Massachusetts
$2.38M

Top Sellers

1
SCM
1
Soleus Capital Management
Connecticut
$0
2
Adage Capital Partners
2
Adage Capital Partners
Massachusetts
$3.57M
3
CH
3
CVI Holdings
Delaware
$716K
4
Fidelity Investments
4
Fidelity Investments
Massachusetts
$3.61M
5
PAMP
5
Polar Asset Management Partners
Ontario, Canada
$0
Name Market Value Shares Shares
Change 		Shares
Change %
Federated Hermes
1
Federated Hermes
Pennsylvania
$22.9M 12,852,654 – –
NMC
2
NEA Management Company
Maryland
$11.6M 6,467,802 – –
RCM
3
RA Capital Management
Massachusetts
$11.2M 6,250,000 – –
VC
4
Vivo Capital
California
$8.93M 5,000,000 – –
OCA
5
Octagon Capital Advisors
New York
$7.61M 4,263,701 +4,263,701 New
Vanguard Group
6
Vanguard Group
Pennsylvania
$7.23M 4,050,863 +3,310,648 +447%
BlackRock
7
BlackRock
New York
$7.08M 3,968,857 +3,900,826 +5,734%
DTC
8
Deep Track Capital
Connecticut
$5.82M 3,262,564 -4,002 -0.1%
Fidelity Investments
9
Fidelity Investments
Massachusetts
$3.61M 2,022,600 -900,000 -31%
Adage Capital Partners
10
Adage Capital Partners
Massachusetts
$3.57M 2,000,000 -1,679,854 -46%
OM
11
Opaleye Management
Massachusetts
$2.63M 1,475,000 +1,304,692 +766%
Geode Capital Management
12
Geode Capital Management
Massachusetts
$2.38M 1,333,509 +1,172,919 +730%
Millennium Management
13
Millennium Management
New York
$2.17M 1,215,581 -659,645 -35%
State Street
14
State Street
Massachusetts
$1.73M 967,502 +925,783 +2,219%
WP
15
Woodline Partners
California
$1.69M 947,685 +947,685 New
Alyeska Investment Group
16
Alyeska Investment Group
Illinois
$1.67M 937,500 – –
DCM
17
DAFNA Capital Management
California
$1.6M 895,200 -175,348 -16%
CH
18
CVI Holdings
Delaware
$716K 401,012 -1,005,238 -71%
Victory Capital Management
19
Victory Capital Management
Texas
$645K 361,386 -6,760 -2%
ECM
20
ExodusPoint Capital Management
New York
$588K 329,639 +329,639 New
Hudson Bay Capital Management
21
Hudson Bay Capital Management
Connecticut
$446K 249,940 -375,060 -60%
Bank of New York Mellon
22
Bank of New York Mellon
New York
$352K 197,193 +197,193 New
MIM
23
Monashee Investment Management
Massachusetts
$352K 197,049 -427,951 -68%
SCM
24
Sarissa Capital Management
Connecticut
$331K 185,183 – –
Charles Schwab
25
Charles Schwab
California
$319K 178,879 +178,879 New
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