DAFNA Capital Management’s Regulus Therapeutics RGLS Stock Holding History

Quarter	Market Value	Status	Shares	Shares Change %	Trade Value	Portfolio Weight	Portfolio Position
2025 Q2	–	Sell	-847,176	Closed	-$1.48M	–	79
2025 Q1	$1.48M	Sell	847,176 -28,024	-3%	-$49K	0.42%	44
2024 Q4	$1.38M	Sell	875,200 -20,000	-2%	-$31.6K	0.35%	49
2024 Q3	$1.41M	Hold	895,200	–	–	0.33%	56
2024 Q2	$1.6M	Sell	895,200 -175,348	-16%	-$313K	0.38%	48
2024 Q1	$3.08M	Sell	1,070,548 -40,501	-4%	-$117K	0.7%	35
2023 Q4	$1.42M	Hold	1,111,049	–	–	0.34%	53
2023 Q3	$1.52M	Hold	1,111,049	–	–	0.47%	43
2023 Q2	$1.63M	Buy	1,111,049 +555,494	+100%	+$817K	0.45%	43
2023 Q1	$471K	Hold	555,555	–	–	0.14%	61
2022 Q4	$761K	Hold	555,555	–	–	0.21%	57
2022 Q3	$944K	Hold	555,555	–	–	0.25%	60
2022 Q2	$1.15M	Sell	555,555 -5,000,000	-90%	-$10.4M	0.31%	60
2022 Q1	$1.66M	Hold	5,555,555	–	–	0.43%	57
2021 Q4	$1.75M	Buy	+5,555,555	New	+$1.75M	0.44%	48
2016 Q4	–	Sell	-421,500	Closed	-$1.39M	–	72
2016 Q3	$1.39M	Hold	421,500	–	–	0.97%	37
2016 Q2	$1.22M	Buy	421,500 +30,000	+8%	+$86.7K	0.97%	36
2016 Q1	$2.71M	Buy	391,500 +301,500	+335%	+$2.09M	2.34%	14
2015 Q4	$785K	Hold	90,000	–	–	0.7%	40
2015 Q3	$589K	Buy	+90,000	New	+$589K	0.58%	45