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RGLS

Regulus Therapeutics
RGLS

Delisted

RGLS was delisted on the 24th of June, 2025.

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103 hedge funds and large institutions have $299M invested in Regulus Therapeutics in 2015 Q4 according to their latest regulatory filings, with 20 funds opening new positions, 34 increasing their positions, 29 reducing their positions, and 8 closing their positions.

New
Increased
Maintained
Reduced
Closed

1,559% more call options, than puts

Call options by funds: $12.7M | Put options by funds: $768K

150% more first-time investments, than exits

New positions opened: 20 | Existing positions closed: 8

50% more funds holding in top 10

Funds holding in top 10: 2 → 3 (+1)

32% more capital invested

Capital invested by funds: $226M → $299M (+$72.7M)

17% more repeat investments, than reductions

Existing positions increased: 34 | Existing positions reduced: 29

12% more funds holding

Funds holding: 92 → 103 (+11)

Holders
103
Holders Change
+11
Holders Change %
+11.96%
% of All Funds
2.7%
Holding in Top 10
3
Holding in Top 10 Change
+1
Holding in Top 10 Change %
+50%
% of All Funds
0.08%
New
20
Increased
34
Reduced
29
Closed
8
Calls
$12.7M
Puts
$768K
Net Calls
+$12M
Net Calls Change
+$4.59M

Top Buyers

Rank Fund Capital Flow
1
UBS AM
UBS AM
Illinois
+$3.74M
2
CPIM
Columbia Partners Investment Management
Virginia
+$3.54M
3
OAM
Oxford Asset Management
United Kingdom
+$2.18M
4
TI
Trexquant Investment
Connecticut
+$940K
5
DCM
Driehaus Capital Management
Illinois
+$782K

Top Sellers

Rank Fund Capital Flow
1
CAM
Cormorant Asset Management
Massachusetts
-$7.23M
2
RCM
RA Capital Management
Massachusetts
-$4.65M
3
Susquehanna International Group
Susquehanna International Group
Pennsylvania
-$2.51M
4
OIM
Oracle Investment Management
Connecticut
-$2.45M
5
SM
Sabby Management
Florida
-$1.22M
Name Holding Trade Value Shares
Change 		Change in
Stake
CWG
26
C WorldWide Group
Denmark
$1.4M -$1.17M -1,167 -47%
Ameriprise
27
Ameriprise
Minnesota
$1.25M -$975K -973 -45%
CS
28
Credit Suisse
Switzerland
$1.25M +$74.2K +74 +7%
TAM
29
Tocqueville Asset Management
New York
$1.2M -$31.1K -31 -3%
Bank of New York Mellon
30
Bank of New York Mellon
New York
$1.13M +$102K +102 +10%
T. Rowe Price Associates
31
T. Rowe Price Associates
Maryland
$1.09M +$46.1K +46 +5%
TI
32
Trexquant Investment
Connecticut
$982K +$940K +938 New
TRSOTSOK
33
Teachers Retirement System of the State of Kentucky
Kentucky
$950K – – –
D.E. Shaw & Co
34
D.E. Shaw & Co
New York
$935K +$463K +462 +107%
BIM
35
BlackRock Investment Management
Delaware
$856K +$2K +2 +0.2%
DCM
36
Driehaus Capital Management
Illinois
$817K +$782K +780 New
TCIM
37
TIAA CREF Investment Management
New York
$794K -$45.1K -45 -6%
DCM
38
DAFNA Capital Management
California
$785K – – –
Susquehanna International Group
39
Susquehanna International Group
Pennsylvania
$710K -$2.51M -2,508 -79%
Deutsche Bank
40
Deutsche Bank
Germany
$608K -$14K -14 -2%
USAA
41
United Services Automobile Association
Texas
$606K +$7.02K +7 +1%
AA
42
ALPS Advisors
Colorado
$601K +$576K +575 New
LCM
43
Landscape Capital Management
New Jersey
$490K +$469K +468 New
NFA
44
Nationwide Fund Advisors
Ohio
$471K +$299K +298 +196%
Millennium Management
45
Millennium Management
New York
$465K +$446K +445 New
California State Teachers Retirement System (CalSTRS)
46
California State Teachers Retirement System (CalSTRS)
California
$457K +$8.02K +8 +2%
TMC
47
Trellus Management Company
Florida
$451K -$403K -402 -48%
BCM
48
Bridgeway Capital Management
Texas
$436K – – –
Macquarie Group
49
Macquarie Group
Australia
$436K – – –
ProShare Advisors
50
ProShare Advisors
Maryland
$403K +$32.1K +32 +9%
1
2
3 4 5

RGLS Hedge Fund Activity: Q4 2015 in Review

103 of the 3,812 institutional investors tracked by Wall St. Rank reported a position in Regulus Therapeutics (RGLS) for Q4 2015, worth a combined $299M — up 32% from $226M a quarter earlier.

Buyers outnumbered sellers: 20 funds opened new RGLS positions and 8 closed out — a net gain of 12 holders — while 34 added to existing stakes and 29 trimmed.

The largest buyer was UBS AM, adding an estimated $3.74M. The largest seller was Cormorant Asset Management, cutting an estimated $7.23M.

  • 103 institutional investors held Regulus Therapeutics (RGLS) as of Q4 2015, up from 92 in Q3 2015.
  • Funds reported $299M of Regulus Therapeutics stock for Q4 2015, up 32% quarter-over-quarter.
  • 20 funds opened new Regulus Therapeutics positions in Q4 2015 and 8 closed out, a net change of +12 holders.
  • The largest Regulus Therapeutics buyer in Q4 2015 was UBS AM, an estimated $3.74M added.
  • The largest Regulus Therapeutics seller in Q4 2015 was Cormorant Asset Management, an estimated $7.23M sold.

Based on aggregated 13F filings for Q4 2015.