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Protagonist Therapeutics
PTGX

Overview Fund Activity

271 hedge funds and large institutions have $3.92B invested in Protagonist Therapeutics in 2025 Q2 according to their latest regulatory filings, with 50 funds opening new positions, 119 increasing their positions, 77 reducing their positions, and 49 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
271
Holders Change
-3
Holders Change %
-1.09%
% of All Funds
3.63%
Holding in Top 10
14
Holding in Top 10 Change
–
Holding in Top 10 Change %
–
% of All Funds
0.19%
New
50
Increased
119
Reduced
77
Closed
49
Calls
$18.4M
Puts
$20.8M
Net Calls
-$2.39M
Net Calls Change
-$21.6M

Top Buyers

1
UBS Group
UBS Group
Switzerland
$138M
2
CC
Commodore Capital
New York
$59.4M
3
Adage Capital Partners
Adage Capital Partners
Massachusetts
$60.4M
4
BI
BVF Inc
California
$177M
5
Holocene Advisors
Holocene Advisors
New York
$29.3M

Top Sellers

1
T. Rowe Price Associates
T. Rowe Price Associates
Maryland
$51.8M
2
Focus Partners Wealth
Focus Partners Wealth
Massachusetts
$0
3
NVCHI
New Vernon Capital Holdings II
New Jersey
$398K
4
AGP
Artia Global Partners
Florida
$1.27M
5
Qube Research & Technologies (QRT)
Qube Research & Technologies (QRT)
United Kingdom
$3.81M
Name Holding Trade Value Shares
Change 		Shares
Change %
Jacobs Levy Equity Management
276
Jacobs Levy Equity Management
New Jersey
– -$6.22M -128,654 Closed
NFGH
277
Nan Fung Group Holdings
Hong Kong
– -$5.87M -121,400 Closed
EF
278
Empowered Funds
Pennsylvania
– -$4.96M -102,532 Closed
Lazard Asset Management
279
Lazard Asset Management
New York
– -$4.66M -96,420 Closed
ACM
280
Aquilo Capital Management
California
– -$3.95M -81,692 Closed
HF
281
HRT Financial
New York
– -$3.35M -69,242 Closed
TF
282
Trek Financial
Arizona
– -$2.82M -58,413 Closed
JF
283
Jump Financial
Illinois
– -$2.75M -56,780 Closed
D.E. Shaw & Co
284
D.E. Shaw & Co
New York
– -$2.29M -47,361 Closed
Tudor Investment Corp
285
Tudor Investment Corp
Connecticut
– -$2.06M -42,583 Closed
CF
286
Corebridge Financial
Texas
– -$1.5M -31,020 Closed
HWAM
287
Hennion & Walsh Asset Management
New Jersey
– -$1.26M -26,066 Closed
QC
288
Quadrature Capital
United Kingdom
– -$1.26M -26,061 Closed
JG
289
Jain Global
New York
– -$1.2M -24,867 Closed
CAS
290
Coppell Advisory Solutions
Texas
– -$947K -20,765 Closed
YIH
291
Y-Intercept (HK)
Hong Kong
– -$975K -20,169 Closed
Verition Fund Management
292
Verition Fund Management
Connecticut
– -$960K -19,847 Closed
CCIA
293
Campbell & Co Investment Adviser
Maryland
– -$920K -19,015 Closed
Jennison Associates
294
Jennison Associates
New York
– -$886K -18,317 Closed
SRL
295
Scientech Research LLC
New Jersey
– -$884K -18,271 Closed
EGM
296
Engineers Gate Manager
New York
– -$741K -15,327 Closed
SFAM
297
Springhill Fund Asset Management
Hong Kong
– -$622K -12,859 Closed
GCP
298
GSA Capital Partners
United Kingdom
– -$579K -11,963 Closed
MF
299
Magnetar Financial
Illinois
– -$539K -11,154 Closed
QC
300
Quantessence Capital
New York
– -$430K -8,900 Closed
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