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Praxis Precision Medicines
PRAX

100 hedge funds and large institutions have $863M invested in Praxis Precision Medicines in 2021 Q4 according to their latest regulatory filings, with 16 funds opening new positions, 45 increasing their positions, 16 reducing their positions, and 7 closing their positions.

New
Increased
Maintained
Reduced
Closed

181% more repeat investments, than reductions

Existing positions increased: 45 | Existing positions reduced: 16

129% more first-time investments, than exits

New positions opened: 16 | Existing positions closed: 7

9% more capital invested

Capital invested by funds: $792M → $863M (+$71.3M)

9% more funds holding

Funds holding: 92 → 100 (+8)

0.13% more ownership

Funds ownership: 6.38% → 6.51% (+0.13%)

0% more funds holding in top 10

Funds holding in top 10: 2 → 2 (0)

Holders
100
Holders Change
+8
Holders Change %
+8.7%
% of All Funds
1.54%
Holding in Top 10
2
Holding in Top 10 Change
–
Holding in Top 10 Change %
–
% of All Funds
0.03%
New
16
Increased
45
Reduced
16
Closed
7
Calls
$572K
Puts
–
Net Calls
+$572K
Net Calls Change
+$166K

Top Buyers

Rank Fund Capital Flow
1
State Street
State Street
Massachusetts
+$14.9M
2
BlackRock
BlackRock
New York
+$6.88M
3
Point72 Asset Management
Point72 Asset Management
Connecticut
+$6.05M
4
AllianceBernstein
AllianceBernstein
Tennessee
+$4.47M
5
PHS
PFM Health Sciences
California
+$3.53M

Top Sellers

Rank Fund Capital Flow
1
Blackstone Inc
Blackstone Inc
New York
-$8.73M
2
CAM
Cormorant Asset Management
Massachusetts
-$5.31M
3
GTC
Ghost Tree Capital
New York
-$4.62M
4
Verition Fund Management
Verition Fund Management
Connecticut
-$3.91M
5
Marshall Wace
Marshall Wace
United Kingdom
-$3.62M
Name Holding Trade Value Shares
Change 		Change in
Stake
VEA
76
Virtus ETF Advisers
New York
$178K -$24.1K -82 -12%
MLICM
77
Metropolitan Life Insurance Company (MetLife)
New York
$173K +$9.68K +33 +6%
Legal & General Group
78
Legal & General Group
United Kingdom
$156K – – –
Royal Bank of Canada
79
Royal Bank of Canada
Ontario, Canada
$132K +$59.5K +203 +84%
Ensign Peak Advisors
80
Ensign Peak Advisors
Utah
$86K +$85.3K +291 New
Nisa Investment Advisors
81
Nisa Investment Advisors
Missouri
$56K +$74.2K +253 New
AIP
82
Ameritas Investment Partners
Nebraska
$49K – – –
PHK
83
Point72 Hong Kong
Hong Kong
$31K +$30.5K +104 New
TRCT
84
Tower Research Capital (TRC)
New York
$26K +$3.52K +12 +16%
Macquarie Group
85
Macquarie Group
Australia
$24K – – –
US Bancorp
86
US Bancorp
Minnesota
$15K +$10.3K +35 +233%
Rockefeller Capital Management
87
Rockefeller Capital Management
New York
$8K +$293 +1 +4%
S
88
SignatureFD
Georgia
$8K +$5.28K +18 +200%
QT
89
Quantbot Technologies
New York
$7K +$7.92K +27 New
Daiwa Securities Group
90
Daiwa Securities Group
Japan
$3K +$2.64K +9 New
Simplex Trading
91
Simplex Trading
Illinois
$2K +$2.64K +9 New
PA
92
Parallel Advisors
California
$1K -$1.76K -6 -55%
QCG
93
Quadrant Capital Group
Ohio
$1K -$1.47K -5 -63%
Bessemer Group
94
Bessemer Group
New Jersey
$1K – – –
CAPTRUST Financial Advisors
95
CAPTRUST Financial Advisors
North Carolina
$1K – – –
LC
96
Lindbrook Capital
California
$1K – – –
TFO
97
Tarbox Family Office
California
$1K +$1.17K +4 New
Manulife (Manufacturers Life Insurance)
98
Manulife (Manufacturers Life Insurance)
Ontario, Canada
$355 +$4.99K +17 +1%
GTC
99
Ghost Tree Capital
New York
– -$4.62M -16,667 Closed
Healthcare of Ontario Pension Plan (HOOPP) Trust Fund
100
Healthcare of Ontario Pension Plan (HOOPP) Trust Fund
Ontario, Canada
– -$1.52M -5,467 Closed
1 2 3
4
5

PRAX Hedge Fund Activity: Q4 2021 in Review

100 of the 6,498 institutional investors tracked by Wall St. Rank reported a position in Praxis Precision Medicines (PRAX) for Q4 2021, worth a combined $863M — up 9% from $792M a quarter earlier.

Buyers outnumbered sellers: 16 funds opened new PRAX positions and 7 closed out — a net gain of 9 holders — while 45 added to existing stakes and 16 trimmed.

The largest buyer was State Street, adding an estimated $14.9M. The largest seller was Blackstone Inc, cutting an estimated $8.73M.

  • 100 institutional investors held Praxis Precision Medicines (PRAX) as of Q4 2021, up from 92 in Q3 2021.
  • Funds reported $863M of Praxis Precision Medicines stock for Q4 2021, up 9% quarter-over-quarter.
  • 16 funds opened new Praxis Precision Medicines positions in Q4 2021 and 7 closed out, a net change of +9 holders.
  • The largest Praxis Precision Medicines buyer in Q4 2021 was State Street, an estimated $14.9M added.
  • The largest Praxis Precision Medicines seller in Q4 2021 was Blackstone Inc, an estimated $8.73M sold.

Based on aggregated 13F filings for Q4 2021.