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Ionis Pharmaceuticals
IONS

Name Holding Trade Value Shares
Change 		Change in
Stake
Fidelity Investments
1
Fidelity Investments
Massachusetts
$645M +$294K +9,348 +0%
T. Rowe Price Associates
2
T. Rowe Price Associates
Maryland
$380M +$23.7M +752,959 +6%
Vanguard Group
3
Vanguard Group
Pennsylvania
$365M +$6.52M +207,067 +2%
BG
4
Bellevue Group
Switzerland
$315M +$31.7M +1,007,197 +11%
BlackRock
5
BlackRock
New York
$260M +$13.2M +419,429 +5%
AIM
6
ARK Investment Management
Florida
$216M -$45M -1,428,128 -17%
ClearBridge Investments
7
ClearBridge Investments
New York
$179M -$45.5M -1,444,340 -20%
State Street
8
State Street
Massachusetts
$119M +$12.1M +385,061 +11%
Geode Capital Management
9
Geode Capital Management
Massachusetts
$55.5M +$1.65M +52,459 +3%
First Trust Advisors
10
First Trust Advisors
Illinois
$51.1M -$16.9K -537 -0%
Millennium Management
11
Millennium Management
New York
$49.4M +$42.2M +1,340,284 +474%
Thrivent Financial for Lutherans
12
Thrivent Financial for Lutherans
Minnesota
$46.7M +$4.6M +146,235 +11%
Jacobs Levy Equity Management
13
Jacobs Levy Equity Management
New Jersey
$42.8M +$6.8M +216,152 +18%
CCM
14
Camber Capital Management
Massachusetts
$42.3M -$34.9M -1,110,000 -44%
JP Morgan Chase
15
JP Morgan Chase
New York
$38.6M -$36.1M -1,147,661 -47%
Citadel Advisors
16
Citadel Advisors
Florida
$37.2M +$5.4M +171,714 +16%
Swedbank
17
Swedbank
Sweden
$34.1M – – –
Charles Schwab
18
Charles Schwab
California
$33.3M +$746K +23,707 +2%
CS
19
Candriam SCA
Luxembourg
$28.5M +$6.62M +210,276 +29%
Norges Bank
20
Norges Bank
Norway
$25.3M -$9.94M -315,699 -28%
Wells Fargo
21
Wells Fargo
California
$24.7M -$1.33M -42,404 -5%
TD Asset Management
22
TD Asset Management
Ontario, Canada
$22.6M +$10.1M +321,200 +76%
Northern Trust
23
Northern Trust
Illinois
$20.1M +$172K +5,469 +0.8%
PFM
24
Privium Fund Management
Netherlands
$19.2M +$19.8M +630,199 New
Bank of America
25
Bank of America
North Carolina
$18.6M -$3.06M -97,282 -14%
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