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Ionis Pharmaceuticals

Name Holding Trade Value Shares
Change
Change in
Stake
Fidelity Investments
1
Fidelity Investments
Massachusetts
$681M
ClearBridge Investments
2
ClearBridge Investments
New York
$349M +$26.6M +749,398 +9%
Artisan Partners
3
Artisan Partners
Wisconsin
$286M -$7.18M -202,577 -3%
Vanguard Group
4
Vanguard Group
Pennsylvania
$282M -$426K -12,028 -0.2%
BB
5
BB Biotech
Switzerland
$258M -$2.48M -70,000 -1%
WRF
6
Waddell & Reed Financial
Kansas
$213M +$4.62M +130,300 +2%
BFA
7
BlackRock Fund Advisors
California
$160M -$469K -13,240 -0.3%
BIT
8
BlackRock Institutional Trust
California
$120M -$4.29M -121,051 -4%
T. Rowe Price Associates
9
T. Rowe Price Associates
Maryland
$107M -$409K -11,528 -0.4%
State Street
10
State Street
Massachusetts
$104M +$9.53M +268,934 +11%
Franklin Resources
11
Franklin Resources
California
$80.9M +$4.69M +132,449 +7%
PA
12
Pinnacle Associates
New York
$71.7M -$2.45M -69,215 -4%
TAM
13
Tocqueville Asset Management
New York
$71.1M -$1.09M -30,794 -2%
Jennison Associates
14
Jennison Associates
New York
$67.8M +$77.3K +2,182 +0.1%
Northern Trust
15
Northern Trust
Illinois
$53.6M +$782K +22,070 +2%
EAM
16
Eagle Asset Management
Florida
$51.8M +$47.2M +1,333,177 New
AGA
17
Altrinsic Global Advisors
Connecticut
$49M +$33.3M +939,038 +291%
Stifel Financial
18
Stifel Financial
Missouri
$41.3M +$362K +10,208 +1%
Massachusetts Financial Services
19
Massachusetts Financial Services
Massachusetts
$40.2M +$16.7M +471,424 +84%
AllianceBernstein
20
AllianceBernstein
Tennessee
$37.7M -$4.88M -137,760 -12%
GTP
21
Global Thematic Partners
New York
$32.9M -$311K -8,770 -1%
ACM
22
Apex Capital Management
Ohio
$32.8M -$1.62M -45,754 -5%
UBS AM
23
UBS AM
Illinois
$30.7M +$1.19M +33,700 +4%
Goldman Sachs
24
Goldman Sachs
New York
$30.1M -$9.68K -273 -0%
Norges Bank
25
Norges Bank
Norway
$29.2M -$26.7M -752,077 -50%