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Ionis Pharmaceuticals

493 hedge funds and large institutions have $13B invested in Ionis Pharmaceuticals in 2026 Q1 according to their latest regulatory filings, with 74 funds opening new positions, 177 increasing their positions, 156 reducing their positions, and 65 closing their positions.

New
Increased
Maintained
Reduced
Closed

14% more first-time investments, than exits

New positions opened: 74 | Existing positions closed: 65

13% more repeat investments, than reductions

Existing positions increased: 177 | Existing positions reduced: 156

8% more funds holding in top 10

Funds holding in top 10: 1314 (+1)

0% more funds holding

Funds holding: 491493 (+2)

0.72% less ownership

Funds ownership: 105.2%104.48% (-0.72%)

2% less call options, than puts

Call options by funds: $141M | Put options by funds: $144M

4% less capital invested

Capital invested by funds: $13.5B → $13B (-$512M)

Holders
493
Holders Change
+2
Holders Change %
+0.41%
% of All Funds
6.07%
Holding in Top 10
14
Holding in Top 10 Change
+1
Holding in Top 10 Change %
+7.69%
% of All Funds
0.17%
New
74
Increased
177
Reduced
156
Closed
65
Calls
$141M
Puts
$144M
Net Calls
-$2.9M
Net Calls Change
-$54M
Name Holding Trade Value Shares
Change
Change in
Stake
AQR Capital Management
201
AQR Capital Management
Connecticut
$2.16M +$791K +10,021 +53%
SO
202
STRS Ohio
Ohio
$2.16M +$1.97M +24,994 +660%
FAM
203
Fred Alger Management
New York
$2.14M -$787K -9,971 -26%
MOACM
204
Mutual of America Capital Management
New York
$2.11M -$263K -3,333 -11%
WorldQuant Millennium Advisors
205
WorldQuant Millennium Advisors
New York
$2.1M +$830K +10,514 +60%
DIG
206
DeepCurrents Investment Group
New York
$2.06M +$2.16M +27,422 New
ET
207
Entropy Technologies
New York
$2.04M +$2.15M +27,207 New
Bank of Montreal
208
Bank of Montreal
Ontario, Canada
$2M -$772K -9,777 -27%
SC
209
Stempoint Capital
New York
$1.98M +$2.08M +26,385 New
X
210
Xponance
Pennsylvania
$1.98M +$272K +3,443 +15%
PA
211
Profund Advisors
Maryland
$1.97M -$30.5K -386 -1%
JG
212
Jain Global
New York
$1.97M -$26M -329,974 -93%
FFA
213
Florida Financial Advisors
Florida
$1.94M +$2.04M +25,886 New
QCM
214
Qsemble Capital Management
New York
$1.93M -$144K -1,821 -7%
Jones Financial Companies
215
Jones Financial Companies
Missouri
$1.93M +$1.6M +20,240 +312%
Lazard Asset Management
216
Lazard Asset Management
New York
$1.91M -$1.66M -20,992 -45%
TRSOTSOK
217
Teachers Retirement System of the State of Kentucky
Kentucky
$1.81M
Man Group
218
Man Group
United Kingdom
$1.8M -$11.2M -142,029 -86%
Amundi
219
Amundi
France
$1.8M -$34.5M -436,989 -95%
Natixis Advisors
220
Natixis Advisors
Massachusetts
$1.78M +$144K +1,830 +8%
VCM
221
Voleon Capital Management
California
$1.73M +$1.48M +18,759 +437%
WAM
222
Wolverine Asset Management
Illinois
$1.71M -$608K -7,700 -25%
Canada Life
223
Canada Life
Manitoba, Canada
$1.67M +$97.9K +1,241 +6%
EI
224
EAM Investors
California
$1.55M -$2.63M -33,306 -62%
AC
225
Allstate Corporation
Illinois
$1.54M +$1.62M +20,565 New