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Ionis Pharmaceuticals

338 hedge funds and large institutions have $4.92B invested in Ionis Pharmaceuticals in 2022 Q4 according to their latest regulatory filings, with 50 funds opening new positions, 115 increasing their positions, 107 reducing their positions, and 54 closing their positions.

New
Increased
Maintained
Reduced
Closed

19% more call options, than puts

Call options by funds: $15.2M | Put options by funds: $12.8M

2.93% more ownership

Funds ownership: 89.04%91.97% (+2.9%)

7% more repeat investments, than reductions

Existing positions increased: 115 | Existing positions reduced: 107

7% less first-time investments, than exits

New positions opened: 50 | Existing positions closed: 54

3% less funds holding

Funds holding: 349338 (-11)

11% less capital invested

Capital invested by funds: $5.53B → $4.92B (-$618M)

20% less funds holding in top 10

Funds holding in top 10: 54 (-1)

Holders
338
Holders Change
-11
Holders Change %
-3.15%
% of All Funds
5.43%
Holding in Top 10
4
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-20%
% of All Funds
0.06%
New
50
Increased
115
Reduced
107
Closed
54
Calls
$15.2M
Puts
$12.8M
Net Calls
+$2.46M
Net Calls Change
-$7.76M
Name Holding Trade Value Shares
Change
Change in
Stake
MSRPS
201
Maryland State Retirement & Pension System
Maryland
$414K +$461K +10,950 New
Osaic Holdings
202
Osaic Holdings
Arizona
$408K -$29.7K -706 -6%
HMS
203
Hanseatic Management Services
New Mexico
$408K -$7.66K -182 -2%
Vontobel Holding
204
Vontobel Holding
Switzerland
$406K -$14.8K -353 -3%
Verition Fund Management
205
Verition Fund Management
Connecticut
$397K +$442K +10,512 New
OAM
206
Oppenheimer Asset Management
New York
$392K -$19.6K -465 -4%
MAM
207
Martingale Asset Management
Massachusetts
$391K +$27.3K +648 +7%
WA
208
Waddell & Associates
Tennessee
$379K
Grantham, Mayo, Van Otterloo & Co (GMO)
209
Grantham, Mayo, Van Otterloo & Co (GMO)
Massachusetts
$366K +$408K +9,700 New
Cambridge Investment Research Advisors
210
Cambridge Investment Research Advisors
Iowa
$361K -$57.5K -1,367 -13%
CAPTRUST Financial Advisors
211
CAPTRUST Financial Advisors
North Carolina
$360K +$401K +9,528 New
PNC Financial Services Group
212
PNC Financial Services Group
Pennsylvania
$350K -$23.6K -562 -6%
BRWA
213
B. Riley Wealth Advisors
Florida
$330K +$59.1K +1,404 +19%
WI
214
WrapManager Inc
California
$321K -$14K -334 -4%
MIM
215
MetLife Investment Management
New Jersey
$305K -$8.62K -205 -2%
HKAM
216
Horizon Kinetics Asset Management
New York
$302K
NIM
217
Nicollet Investment Management
Minnesota
$300K -$24K -570 -7%
VEA
218
Virtus ETF Advisers
New York
$298K +$36.6K +871 +12%
CB
219
Commerce Bank
Missouri
$292K +$13.1K +311 +4%
NFC
220
Northeast Financial Consultants
Connecticut
$292K
EMG
221
ETF Managers Group
New Jersey
$289K +$322K +7,649 New
URS
222
Utah Retirement Systems
Utah
$283K
AQR Capital Management
223
AQR Capital Management
Connecticut
$282K -$5.93K -141 -2%
TRCT
224
Tower Research Capital (TRC)
New York
$275K -$189K -4,483 -38%
TCM
225
Tanaka Capital Management
New York
$269K

IONS Hedge Fund Activity: Q4 2022 in Review

338 of the 6,221 institutional investors tracked by Wall St. Rank reported a position in Ionis Pharmaceuticals (IONS) for Q4 2022, worth a combined $4.92B — down 11% from $5.53B a quarter earlier.

Sellers outnumbered buyers: 54 funds closed out of IONS and 50 opened new positions — a net loss of 4 holders — while 107 trimmed existing stakes and 115 added.

The largest buyer was OrbiMed, adding an estimated $51.5M. The largest seller was BVF Inc, cutting an estimated $73.7M.

  • 338 institutional investors held Ionis Pharmaceuticals (IONS) as of Q4 2022, down from 349 in Q3 2022.
  • Funds reported $4.92B of Ionis Pharmaceuticals stock for Q4 2022, down 11% quarter-over-quarter.
  • 50 funds opened new Ionis Pharmaceuticals positions in Q4 2022 and 54 closed out, a net change of -4 holders.
  • The largest Ionis Pharmaceuticals buyer in Q4 2022 was OrbiMed, an estimated $51.5M added.
  • The largest Ionis Pharmaceuticals seller in Q4 2022 was BVF Inc, an estimated $73.7M sold.

Based on aggregated 13F filings for Q4 2022.