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Ionis Pharmaceuticals

339 hedge funds and large institutions have $5.01B invested in Ionis Pharmaceuticals in 2025 Q1 according to their latest regulatory filings, with 54 funds opening new positions, 102 increasing their positions, 122 reducing their positions, and 61 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
339
Holders Change
-12
Holders Change %
-3.42%
% of All Funds
4.6%
Holding in Top 10
6
Holding in Top 10 Change
+2
Holding in Top 10 Change %
+50%
% of All Funds
0.08%
New
54
Increased
102
Reduced
122
Closed
61
Calls
$24.8M
Puts
$18.8M
Net Calls
+$6M
Net Calls Change
+$10.5M
Name Holding Trade Value Shares
Change
Shares
Change %
TC
176
TwinBeech Capital
New York
$481K +$481K +15,938 New
Public Employees Retirement Association of Colorado
177
Public Employees Retirement Association of Colorado
Colorado
$470K
Envestnet Asset Management
178
Envestnet Asset Management
Illinois
$454K -$1.14M -37,649 -71%
Jones Financial Companies
179
Jones Financial Companies
Missouri
$428K +$137K +4,397 +47%
NSAM
180
North Star Asset Management
Wisconsin
$411K -$905 -30 -0.2%
SWP
181
Significant Wealth Partners
Illinois
$410K +$81.5K +2,700 +25%
WP
182
Westmount Partners
California
$391K -$15.1K -501 -4%
PHK
183
Point72 Hong Kong
Hong Kong
$388K +$388K +12,862 New
HKAM
184
Horizon Kinetics Asset Management
New York
$376K
XT
185
XTX Topco
Cayman Islands
$374K -$391K -12,958 -51%
Northwestern Mutual Wealth Management
186
Northwestern Mutual Wealth Management
Wisconsin
$373K +$31.1K +1,031 +9%
IIM
187
INTECH Investment Management
Florida
$368K +$368K +12,207 New
Brown Advisory
188
Brown Advisory
Maryland
$363K -$21.2K -704 -6%
SP
189
SIH Partners
Delaware
$362K +$362K +11,999 New
FC
190
FORA Capital
Florida
$349K +$349K +11,570 New
Twin Tree Management
191
Twin Tree Management
Texas
$343K -$2.34M -77,515 -87%
P
192
&Partners
Tennessee
$343K +$21.4K +687 +7%
PL
193
Plancorp LLC
Missouri
$336K
PNC Financial Services Group
194
PNC Financial Services Group
Pennsylvania
$331K -$211 -7 -0.1%
SCM
195
Suvretta Capital Management
New York
$326K
AGWCA
196
Annis Gardner Whiting Capital Advisors
Florida
$324K
AB
197
Amalgamated Bank
New York
$319K +$8.48K +281 +3%
HA
198
Harbor Advisors
Florida
$317K
Principal Financial Group
199
Principal Financial Group
Iowa
$315K -$95.6K -3,169 -23%
CM
200
Capula Management
Cayman Islands
$313K +$313K +10,382 New