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Ionis Pharmaceuticals

338 hedge funds and large institutions have $4.92B invested in Ionis Pharmaceuticals in 2022 Q4 according to their latest regulatory filings, with 50 funds opening new positions, 115 increasing their positions, 107 reducing their positions, and 54 closing their positions.

New
Increased
Maintained
Reduced
Closed

19% more call options, than puts

Call options by funds: $15.2M | Put options by funds: $12.8M

2.93% more ownership

Funds ownership: 89.04%91.97% (+2.9%)

7% more repeat investments, than reductions

Existing positions increased: 115 | Existing positions reduced: 107

7% less first-time investments, than exits

New positions opened: 50 | Existing positions closed: 54

3% less funds holding

Funds holding: 349338 (-11)

11% less capital invested

Capital invested by funds: $5.53B → $4.92B (-$618M)

20% less funds holding in top 10

Funds holding in top 10: 54 (-1)

Holders
338
Holders Change
-11
Holders Change %
-3.15%
% of All Funds
5.43%
Holding in Top 10
4
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-20%
% of All Funds
0.06%
New
50
Increased
115
Reduced
107
Closed
54
Calls
$15.2M
Puts
$12.8M
Net Calls
+$2.46M
Net Calls Change
-$7.76M
Name Holding Trade Value Shares
Change
Change in
Stake
Walleye Capital
151
Walleye Capital
New York
$984K -$2.52M -59,909 -70%
SO
152
STRS Ohio
Ohio
$974K +$357K +8,483 +49%
DTL
153
Dynamic Technology Lab
Singapore
$966K +$1.08M +25,580 New
CF
154
Cantor Fitzgerald
New York
$864K +$962K +22,880 New
KAS
155
Kestra Advisory Services
Texas
$847K -$21.5K -512 -2%
Commonwealth Equity Services
156
Commonwealth Equity Services
Massachusetts
$781K -$22.8K -543 -3%
CRWM
157
Castle Rock Wealth Management
California
$763K -$21K -500 -3%
EGM
158
Engineers Gate Manager
New York
$755K +$567K +13,484 +208%
Skandinaviska Enskilda Banken (SEB)
159
Skandinaviska Enskilda Banken (SEB)
Sweden
$745K -$48K -1,142 -5%
Public Employees Retirement Association of Colorado
160
Public Employees Retirement Association of Colorado
Colorado
$740K
ESCM
161
Echo Street Capital Management
New York
$722K +$543K +12,910 +208%
Zurich Cantonal Bank
162
Zurich Cantonal Bank
Switzerland
$706K +$82.6K +1,963 +12%
VAS
163
Vestmark Advisory Solutions
Massachusetts
$703K -$277K -6,597 -26%
KOC
164
Koss-Olinger Consulting
Florida
$701K -$731K -17,376 -48%
Handelsbanken Fonder
165
Handelsbanken Fonder
Sweden
$699K
X
166
Xponance
Pennsylvania
$669K +$91.3K +2,170 +14%
Mariner
167
Mariner
Kansas
$663K +$437K +10,401 +146%
Natixis Advisors
168
Natixis Advisors
Massachusetts
$612K +$16.2K +385 +2%
AT
169
American Trust
Kentucky
$603K +$672K +15,970 New
PA
170
Profund Advisors
Maryland
$598K +$15.5K +368 +2%
Victory Capital Management
171
Victory Capital Management
Texas
$596K -$336 -8 -0.1%
Group One Trading
172
Group One Trading
Illinois
$584K +$650K +15,463 New
QC
173
Quantedge Capital
Singapore
$570K +$635K +15,100 New
CCIA
174
Campbell & Co Investment Adviser
Maryland
$567K +$632K +15,018 New
US Bancorp
175
US Bancorp
Minnesota
$560K -$58K -1,378 -9%

IONS Hedge Fund Activity: Q4 2022 in Review

338 of the 6,221 institutional investors tracked by Wall St. Rank reported a position in Ionis Pharmaceuticals (IONS) for Q4 2022, worth a combined $4.92B — down 11% from $5.53B a quarter earlier.

Sellers outnumbered buyers: 54 funds closed out of IONS and 50 opened new positions — a net loss of 4 holders — while 107 trimmed existing stakes and 115 added.

The largest buyer was OrbiMed, adding an estimated $51.5M. The largest seller was BVF Inc, cutting an estimated $73.7M.

  • 338 institutional investors held Ionis Pharmaceuticals (IONS) as of Q4 2022, down from 349 in Q3 2022.
  • Funds reported $4.92B of Ionis Pharmaceuticals stock for Q4 2022, down 11% quarter-over-quarter.
  • 50 funds opened new Ionis Pharmaceuticals positions in Q4 2022 and 54 closed out, a net change of -4 holders.
  • The largest Ionis Pharmaceuticals buyer in Q4 2022 was OrbiMed, an estimated $51.5M added.
  • The largest Ionis Pharmaceuticals seller in Q4 2022 was BVF Inc, an estimated $73.7M sold.

Based on aggregated 13F filings for Q4 2022.