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Ionis Pharmaceuticals

338 hedge funds and large institutions have $4.92B invested in Ionis Pharmaceuticals in 2022 Q4 according to their latest regulatory filings, with 50 funds opening new positions, 115 increasing their positions, 107 reducing their positions, and 54 closing their positions.

New
Increased
Maintained
Reduced
Closed

19% more call options, than puts

Call options by funds: $15.2M | Put options by funds: $12.8M

2.93% more ownership

Funds ownership: 89.04%91.97% (+2.9%)

7% more repeat investments, than reductions

Existing positions increased: 115 | Existing positions reduced: 107

7% less first-time investments, than exits

New positions opened: 50 | Existing positions closed: 54

3% less funds holding

Funds holding: 349338 (-11)

11% less capital invested

Capital invested by funds: $5.53B → $4.92B (-$618M)

20% less funds holding in top 10

Funds holding in top 10: 54 (-1)

Holders
338
Holders Change
-11
Holders Change %
-3.15%
% of All Funds
5.43%
Holding in Top 10
4
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-20%
% of All Funds
0.06%
New
50
Increased
115
Reduced
107
Closed
54
Calls
$15.2M
Puts
$12.8M
Net Calls
+$2.46M
Net Calls Change
-$7.76M
Name Holding Trade Value Shares
Change
Change in
Stake
RPAM
126
Rhenman & Partners Asset Management
Sweden
$1.89M
TI
127
Trexquant Investment
Connecticut
$1.77M -$363K -8,619 -16%
SEI Investments
128
SEI Investments
Pennsylvania
$1.74M +$1.13M +26,812 +140%
NSEDCP
129
NJ State Employees Deferred Compensation Plan
New Jersey
$1.59M
HCMT
130
Highland Capital Management (Tennessee)
Tennessee
$1.52M +$60.4K +1,437 +4%
CC
131
Capital Counsel
New York
$1.52M
Teacher Retirement System of Texas
132
Teacher Retirement System of Texas
Texas
$1.45M -$146K -3,466 -8%
Principal Financial Group
133
Principal Financial Group
Iowa
$1.45M -$923K -21,947 -36%
Tudor Investment Corp
134
Tudor Investment Corp
Connecticut
$1.37M +$642K +15,256 +72%
ASRS
135
Arizona State Retirement System
Arizona
$1.36M +$57.5K +1,367 +4%
Envestnet Asset Management
136
Envestnet Asset Management
Illinois
$1.34M -$161K -3,835 -10%
MF
137
Magnetar Financial
Illinois
$1.31M +$1.46M +34,597 New
Janney Montgomery Scott
138
Janney Montgomery Scott
Pennsylvania
$1.25M +$27K +643 +2%
AB
139
Amalgamated Bank
New York
$1.21M +$21.2K +503 +2%
GD
140
Grandfield & Dodd
New York
$1.19M +$101K +2,403 +8%
Bank of Nova Scotia
141
Bank of Nova Scotia
Ontario, Canada
$1.17M +$1.3M +31,000 New
American Century Companies
142
American Century Companies
Missouri
$1.17M +$875K +20,793 +206%
VRS
143
Virginia Retirement Systems
Virginia
$1.16M +$177K +4,200 +16%
Voloridge Investment Management
144
Voloridge Investment Management
Florida
$1.16M +$1.29M +30,709 New
Toronto Dominion Bank
145
Toronto Dominion Bank
Ontario, Canada
$1.16M -$25.2K -600 -2%
EP
146
Edgestream Partners
New Jersey
$1.03M +$1.15M +27,393 New
PI
147
PineBridge Investments
New York
$1.02M +$1.13M +26,959 New
RJFSA
148
Raymond James Financial Services Advisors
Florida
$1.01M -$246K -5,839 -18%
Federated Hermes
149
Federated Hermes
Pennsylvania
$1M +$19K +452 +2%
Canada Life
150
Canada Life
Manitoba, Canada
$993K +$379K +9,005 +53%

IONS Hedge Fund Activity: Q4 2022 in Review

338 of the 6,221 institutional investors tracked by Wall St. Rank reported a position in Ionis Pharmaceuticals (IONS) for Q4 2022, worth a combined $4.92B — down 11% from $5.53B a quarter earlier.

Sellers outnumbered buyers: 54 funds closed out of IONS and 50 opened new positions — a net loss of 4 holders — while 107 trimmed existing stakes and 115 added.

The largest buyer was OrbiMed, adding an estimated $51.5M. The largest seller was BVF Inc, cutting an estimated $73.7M.

  • 338 institutional investors held Ionis Pharmaceuticals (IONS) as of Q4 2022, down from 349 in Q3 2022.
  • Funds reported $4.92B of Ionis Pharmaceuticals stock for Q4 2022, down 11% quarter-over-quarter.
  • 50 funds opened new Ionis Pharmaceuticals positions in Q4 2022 and 54 closed out, a net change of -4 holders.
  • The largest Ionis Pharmaceuticals buyer in Q4 2022 was OrbiMed, an estimated $51.5M added.
  • The largest Ionis Pharmaceuticals seller in Q4 2022 was BVF Inc, an estimated $73.7M sold.

Based on aggregated 13F filings for Q4 2022.