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Ionis Pharmaceuticals

493 hedge funds and large institutions have $13B invested in Ionis Pharmaceuticals in 2026 Q1 according to their latest regulatory filings, with 74 funds opening new positions, 177 increasing their positions, 156 reducing their positions, and 65 closing their positions.

New
Increased
Maintained
Reduced
Closed

14% more first-time investments, than exits

New positions opened: 74 | Existing positions closed: 65

13% more repeat investments, than reductions

Existing positions increased: 177 | Existing positions reduced: 156

8% more funds holding in top 10

Funds holding in top 10: 1314 (+1)

0% more funds holding

Funds holding: 491493 (+2)

0.72% less ownership

Funds ownership: 105.2%104.48% (-0.72%)

2% less call options, than puts

Call options by funds: $141M | Put options by funds: $144M

4% less capital invested

Capital invested by funds: $13.5B → $13B (-$512M)

Holders
493
Holders Change
+2
Holders Change %
+0.41%
% of All Funds
6.07%
Holding in Top 10
14
Holding in Top 10 Change
+1
Holding in Top 10 Change %
+7.69%
% of All Funds
0.17%
New
74
Increased
177
Reduced
156
Closed
65
Calls
$141M
Puts
$144M
Net Calls
-$2.9M
Net Calls Change
-$54M
Name Holding Trade Value Shares
Change
Change in
Stake
SEI Investments
101
SEI Investments
Pennsylvania
$11.8M +$3.26M +41,305 +36%
CP
102
CenterBook Partners
Connecticut
$11.3M -$240K -3,037 -2%
Manulife (Manufacturers Life Insurance)
103
Manulife (Manufacturers Life Insurance)
Ontario, Canada
$11.2M -$292K -3,703 -2%
ACM
104
Aquatic Capital Management
Illinois
$11.1M +$1.15M +14,553 +11%
Citigroup
105
Citigroup
New York
$11M +$4.51M +57,201 +64%
AGP
106
Artia Global Partners
Florida
$10.8M
Capital Fund Management (CFM)
107
Capital Fund Management (CFM)
France
$10.7M +$11.2M +142,201 New
Fisher Asset Management
108
Fisher Asset Management
Washington
$10.6M -$5.6K -71 -0.1%
VAM
109
Vanguard Asset Management
$10.3M +$10.9M +137,507 New
EDRH
110
Edmond de Rothschild Holding
Switzerland
$10.3M +$1.18M +15,000 +12%
State Board of Administration of Florida Retirement System
111
State Board of Administration of Florida Retirement System
Florida
$10.2M
EGM
112
Engineers Gate Manager
New York
$10M +$8.81M +111,636 +503%
B
113
Braidwell
Connecticut
$9.83M +$10.3M +130,862 New
IC
114
Ikarian Capital
Texas
$9.54M -$5.92M -75,000 -37%
HP
115
HealthInvest Partners
Sweden
$9.4M -$5.09M -64,504 -70%
IHAM
116
Integral Health Asset Management
New York
$9.39M +$9.87M +125,000 New
GLA
117
Great Lakes Advisors
Illinois
$8.93M -$2.39M -30,254 -20%
AG
118
Algert Global
California
$8.75M -$840K -10,642 -8%
SAM
119
SEB Asset Management
$8.59M +$9.02M +114,334 New
Nomura Holdings
120
Nomura Holdings
Japan
$8.57M -$58M -734,735 -87%
Aberdeen Group
121
Aberdeen Group
United Kingdom
$8.55M +$6.7M +84,917 +294%
KCM
122
Kennedy Capital Management
Missouri
$8.4M +$200K +2,539 +2%
EAM
123
Exome Asset Management
New York
$8.26M -$509K -6,451 -6%
Victory Capital Management
124
Victory Capital Management
Texas
$8.17M +$2.21M +28,015 +35%
WG
125
Winton Group
United Kingdom
$8M +$8.41M +106,532 New