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Ionis Pharmaceuticals

338 hedge funds and large institutions have $4.92B invested in Ionis Pharmaceuticals in 2022 Q4 according to their latest regulatory filings, with 50 funds opening new positions, 115 increasing their positions, 107 reducing their positions, and 54 closing their positions.

New
Increased
Maintained
Reduced
Closed

19% more call options, than puts

Call options by funds: $15.2M | Put options by funds: $12.8M

2.93% more ownership

Funds ownership: 89.04%91.97% (+2.9%)

7% more repeat investments, than reductions

Existing positions increased: 115 | Existing positions reduced: 107

7% less first-time investments, than exits

New positions opened: 50 | Existing positions closed: 54

3% less funds holding

Funds holding: 349338 (-11)

11% less capital invested

Capital invested by funds: $5.53B → $4.92B (-$618M)

20% less funds holding in top 10

Funds holding in top 10: 54 (-1)

Holders
338
Holders Change
-11
Holders Change %
-3.15%
% of All Funds
5.43%
Holding in Top 10
4
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-20%
% of All Funds
0.06%
New
50
Increased
115
Reduced
107
Closed
54
Calls
$15.2M
Puts
$12.8M
Net Calls
+$2.46M
Net Calls Change
-$7.76M
Name Holding Trade Value Shares
Change
Change in
Stake
TCM
101
Tekla Capital Management
Massachusetts
$3.32M
Manulife (Manufacturers Life Insurance)
102
Manulife (Manufacturers Life Insurance)
Ontario, Canada
$3.08M -$276K -6,573 -7%
DC
103
Davenport & Co
Virginia
$3.04M -$179K -4,246 -5%
State of New Jersey Common Pension Fund D
104
State of New Jersey Common Pension Fund D
New Jersey
$3.04M
Ohio Public Employees Retirement System (OPERS)
105
Ohio Public Employees Retirement System (OPERS)
Ohio
$2.88M +$9.34K +222 +0.3%
LPL Financial
106
LPL Financial
California
$2.8M -$27K -641 -0.9%
AG
107
Algert Global
California
$2.78M +$530K +12,610 +21%
Canada Pension Plan Investment Board
108
Canada Pension Plan Investment Board
Ontario, Canada
$2.75M +$3.07M +72,900 New
PI
109
PFS Investments
Georgia
$2.72M -$129K -3,077 -4%
VOYA Investment Management
110
VOYA Investment Management
Georgia
$2.65M +$84 +2 +0%
GAM
111
Gotham Asset Management
New York
$2.64M +$1.96M +46,656 +201%
Deutsche Bank
112
Deutsche Bank
Germany
$2.52M +$50.4K +1,199 +2%
Healthcare of Ontario Pension Plan (HOOPP) Trust Fund
113
Healthcare of Ontario Pension Plan (HOOPP) Trust Fund
Ontario, Canada
$2.38M -$1.25M -29,700 -32%
GC
114
Guggenheim Capital
Illinois
$2.35M +$302K +7,190 +13%
Treasurer of the State of North Carolina
115
Treasurer of the State of North Carolina
North Carolina
$2.31M +$32.8K +780 +1%
National Bank of Canada
116
National Bank of Canada
Quebec, Canada
$2.3M +$386K +9,175 +18%
AllianceBernstein
117
AllianceBernstein
Tennessee
$2.21M +$16.9K +402 +0.7%
Susquehanna International Group
118
Susquehanna International Group
Pennsylvania
$2.19M +$715K +17,002 +42%
Ensign Peak Advisors
119
Ensign Peak Advisors
Utah
$2.07M +$950K +22,576 +70%
BFS
120
Bard Financial Services
Connecticut
$2.04M -$1.43M -33,970 -39%
Janus Henderson Group
121
Janus Henderson Group
United Kingdom
$2.03M +$313K +7,442 +16%
DA
122
Duality Advisers
Florida
$2.02M +$2.01M +47,732 +824%
GIA
123
Gateway Investment Advisers
Ohio
$1.93M +$41K +975 +2%
EAM
124
Erste Asset Management
Austria
$1.92M
IIM
125
INTECH Investment Management
Florida
$1.91M -$279K -6,630 -12%

IONS Hedge Fund Activity: Q4 2022 in Review

338 of the 6,221 institutional investors tracked by Wall St. Rank reported a position in Ionis Pharmaceuticals (IONS) for Q4 2022, worth a combined $4.92B — down 11% from $5.53B a quarter earlier.

Sellers outnumbered buyers: 54 funds closed out of IONS and 50 opened new positions — a net loss of 4 holders — while 107 trimmed existing stakes and 115 added.

The largest buyer was OrbiMed, adding an estimated $51.5M. The largest seller was BVF Inc, cutting an estimated $73.7M.

  • 338 institutional investors held Ionis Pharmaceuticals (IONS) as of Q4 2022, down from 349 in Q3 2022.
  • Funds reported $4.92B of Ionis Pharmaceuticals stock for Q4 2022, down 11% quarter-over-quarter.
  • 50 funds opened new Ionis Pharmaceuticals positions in Q4 2022 and 54 closed out, a net change of -4 holders.
  • The largest Ionis Pharmaceuticals buyer in Q4 2022 was OrbiMed, an estimated $51.5M added.
  • The largest Ionis Pharmaceuticals seller in Q4 2022 was BVF Inc, an estimated $73.7M sold.

Based on aggregated 13F filings for Q4 2022.