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Ionis Pharmaceuticals

364 hedge funds and large institutions have $5.55B invested in Ionis Pharmaceuticals in 2021 Q1 according to their latest regulatory filings, with 53 funds opening new positions, 127 increasing their positions, 111 reducing their positions, and 67 closing their positions.

New
Increased
Maintained
Reduced
Closed

73% more call options, than puts

Call options by funds: $56.3M | Put options by funds: $32.5M

14% more repeat investments, than reductions

Existing positions increased: 127 | Existing positions reduced: 111

1.74% more ownership

Funds ownership: 85.94%87.67% (+1.7%)

5% less funds holding

Funds holding: 382364 (-18)

18% less capital invested

Capital invested by funds: $6.8B → $5.55B (-$1.25B)

20% less funds holding in top 10

Funds holding in top 10: 54 (-1)

21% less first-time investments, than exits

New positions opened: 53 | Existing positions closed: 67

Holders
364
Holders Change
-18
Holders Change %
-4.71%
% of All Funds
6.39%
Holding in Top 10
4
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-20%
% of All Funds
0.07%
New
53
Increased
127
Reduced
111
Closed
67
Calls
$56.3M
Puts
$32.5M
Net Calls
+$23.8M
Net Calls Change
-$29.6M
Name Holding Trade Value Shares
Change
Change in
Stake
DY
51
Dowling & Yahnke
California
$13.6M -$9.61M -172,241 -36%
RJA
52
Raymond James & Associates
Florida
$13.6M -$254K -4,559 -1%
CS
53
Candriam SCA
Luxembourg
$13.4M
Bank Julius Baer & Co
54
Bank Julius Baer & Co
Switzerland
$12.9M +$16.1M +287,927 New
TAM
55
Tocqueville Asset Management
New York
$11M -$1.42M -25,405 -9%
California State Teachers Retirement System (CalSTRS)
56
California State Teachers Retirement System (CalSTRS)
California
$11M +$138K +2,468 +1%
Baillie Gifford & Co
57
Baillie Gifford & Co
United Kingdom
$10.7M +$6.23M +111,741 +89%
Citigroup
58
Citigroup
New York
$10.6M +$267K +4,792 +2%
PPA
59
Parametric Portfolio Associates
Washington
$9.97M -$1.12M -20,119 -8%
TCM
60
Tekla Capital Management
Massachusetts
$9.73M +$1.29M +23,170 +12%
MIS
61
Morningstar Investment Services
Illinois
$9.06M +$11.3M +202,707 New
New York State Common Retirement Fund
62
New York State Common Retirement Fund
New York
$8.91M -$1.42M -25,500 -11%
Axa
63
Axa
France
$8.66M +$1.08M +19,282 +11%
Two Sigma Investments
64
Two Sigma Investments
New York
$8.35M +$1.03M +18,515 +11%
PCM
65
Peregrine Capital Management
Minnesota
$7.75M -$332K -5,956 -3%
VanEck Associates
66
VanEck Associates
New York
$7.64M +$2.42M +43,349 +34%
Citadel Advisors
67
Citadel Advisors
Florida
$7.64M -$25.4M -455,141 -73%
State Board of Administration of Florida Retirement System
68
State Board of Administration of Florida Retirement System
Florida
$7.6M -$373K -6,680 -4%
SIM
69
Sonora Investment Management
Arizona
$7.37M +$721K +12,928 +9%
Jacobs Levy Equity Management
70
Jacobs Levy Equity Management
New Jersey
$7.33M -$2.3M -41,235 -20%
Deutsche Bank
71
Deutsche Bank
Germany
$7.22M +$265K +4,744 +3%
Royal Bank of Canada
72
Royal Bank of Canada
Ontario, Canada
$7.18M +$498K +8,927 +6%
BBA
73
BLB&B Advisors
Pennsylvania
$7.04M -$59.4K -1,065 -0.7%
SFM
74
Sphera Funds Management
Israel
$6.54M +$2.99M +53,676 +58%
RhumbLine Advisers
75
RhumbLine Advisers
Massachusetts
$6.49M -$413K -7,405 -5%

IONS Hedge Fund Activity: Q1 2021 in Review

364 of the 5,695 institutional investors tracked by Wall St. Rank reported a position in Ionis Pharmaceuticals (IONS) for Q1 2021, worth a combined $5.55B — down 18% from $6.8B a quarter earlier.

Sellers outnumbered buyers: 67 funds closed out of IONS and 53 opened new positions — a net loss of 14 holders — while 111 trimmed existing stakes and 127 added.

The largest buyer was ARK Investment Management, adding an estimated $153M. The largest seller was Invesco, cutting an estimated $57.2M.

  • 364 institutional investors held Ionis Pharmaceuticals (IONS) as of Q1 2021, down from 382 in Q4 2020.
  • Funds reported $5.55B of Ionis Pharmaceuticals stock for Q1 2021, down 18% quarter-over-quarter.
  • 53 funds opened new Ionis Pharmaceuticals positions in Q1 2021 and 67 closed out, a net change of -14 holders.
  • The largest Ionis Pharmaceuticals buyer in Q1 2021 was ARK Investment Management, an estimated $153M added.
  • The largest Ionis Pharmaceuticals seller in Q1 2021 was Invesco, an estimated $57.2M sold.

Based on aggregated 13F filings for Q1 2021.