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Ionis Pharmaceuticals
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Overview Fund Activity

316 hedge funds and large institutions have $5.72B invested in Ionis Pharmaceuticals in 2017 Q4 according to their latest regulatory filings, with 55 funds opening new positions, 89 increasing their positions, 115 reducing their positions, and 38 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
316
Holders Change
+15
Holders Change %
+4.98%
% of All Funds
7.18%
Holding in Top 10
5
Holding in Top 10 Change
-2
Holding in Top 10 Change %
-28.57%
% of All Funds
0.11%
New
55
Increased
89
Reduced
115
Closed
38
Calls
$60.9M
Puts
$73.5M
Net Calls
-$12.6M
Net Calls Change
+$1.97M

Top Buyers

1
BC
1
Boxer Capital
California
$22.6M
2
BB
2
BB Biotech
Switzerland
$409M
3
T. Rowe Price Associates
3
T. Rowe Price Associates
Maryland
$69.8M
4
Royal Bank of Canada
4
Royal Bank of Canada
Ontario, Canada
$20.9M
5
Goldman Sachs
5
Goldman Sachs
New York
$97M

Top Sellers

1
Deutsche Bank
1
Deutsche Bank
Germany
$8.65M
2
Bank of America
2
Bank of America
North Carolina
$42M
3
Wellington Management Group
3
Wellington Management Group
Massachusetts
$548M
4
ClearBridge Investments
4
ClearBridge Investments
New York
$553M
5
Baillie Gifford & Co
5
Baillie Gifford & Co
United Kingdom
$333M
Name Holding Trade Value Shares
Change 		Shares
Change %
Axa
51
Axa
France
$9.95M +$4.79M +95,294 +93%
Millennium Management
52
Millennium Management
New York
$9.86M +$145K +2,874 +1%
California State Teachers Retirement System (CalSTRS)
53
California State Teachers Retirement System (CalSTRS)
California
$9.85M -$154K -3,063 -2%
Morgan Stanley
54
Morgan Stanley
New York
$9.66M -$544K -10,819 -5%
SGAM
55
Smith Group Asset Management
Texas
$8.88M -$342K -6,790 -4%
Susquehanna International Group
56
Susquehanna International Group
Pennsylvania
$8.75M +$3.22M +63,971 +58%
Deutsche Bank
57
Deutsche Bank
Germany
$8.65M -$58.8M -1,169,620 -87%
State Board of Administration of Florida Retirement System
58
State Board of Administration of Florida Retirement System
Florida
$8.57M -$41.2K -820 -0.5%
Two Sigma Investments
59
Two Sigma Investments
New York
$8.56M +$8.3M +164,947 +3,164%
VanEck Associates
60
VanEck Associates
New York
$8.52M -$4.44M -88,358 -34%
RhumbLine Advisers
61
RhumbLine Advisers
Massachusetts
$7.63M -$117K -2,325 -2%
Two Sigma Advisers
62
Two Sigma Advisers
New York
$7.34M +$5.53M +110,000 +306%
Canada Pension Plan Investment Board
63
Canada Pension Plan Investment Board
Ontario, Canada
$7.3M +$1.33M +26,400 +22%
Citadel Advisors
64
Citadel Advisors
Florida
$7.22M +$7.22M +143,458 New
CS
65
Candriam SCA
Luxembourg
$7.14M -$50.3K -1,000 -0.7%
Group One Trading
66
Group One Trading
Illinois
$6.96M -$406K -8,075 -6%
TA
67
Teachers Advisors
New York
$6.74M +$96.2K +1,913 +1%
MWNA
68
Marshall Wace North America
New York
$6.67M +$2.42M +48,046 +57%
TCM
69
Tekla Capital Management
Massachusetts
$6.49M +$6.49M +128,930 New
Natixis Advisors
70
Natixis Advisors
Massachusetts
$6.42M +$41.3K +822 +0.6%
SIM
71
Sonora Investment Management
Arizona
$5.99M +$52K +1,034 +0.9%
GAM
72
Gotham Asset Management
New York
$5.69M -$8.88M -176,531 -61%
Citigroup
73
Citigroup
New York
$5.46M -$1.27M -25,340 -19%
TRSOTSOK
74
Teachers Retirement System of the State of Kentucky
Kentucky
$5.25M -$321K -6,374 -6%
PPA
75
Parametric Portfolio Associates
Washington
$5.13M +$491K +9,764 +11%
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