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Ionis Pharmaceuticals

493 hedge funds and large institutions have $13B invested in Ionis Pharmaceuticals in 2026 Q1 according to their latest regulatory filings, with 74 funds opening new positions, 177 increasing their positions, 156 reducing their positions, and 65 closing their positions.

New
Increased
Maintained
Reduced
Closed

14% more first-time investments, than exits

New positions opened: 74 | Existing positions closed: 65

13% more repeat investments, than reductions

Existing positions increased: 177 | Existing positions reduced: 156

8% more funds holding in top 10

Funds holding in top 10: 1314 (+1)

0% more funds holding

Funds holding: 491493 (+2)

0.72% less ownership

Funds ownership: 105.2%104.48% (-0.72%)

2% less call options, than puts

Call options by funds: $141M | Put options by funds: $144M

4% less capital invested

Capital invested by funds: $13.5B → $13B (-$512M)

Holders
493
Holders Change
+2
Holders Change %
+0.41%
% of All Funds
6.07%
Holding in Top 10
14
Holding in Top 10 Change
+1
Holding in Top 10 Change %
+7.69%
% of All Funds
0.17%
New
74
Increased
177
Reduced
156
Closed
65
Calls
$141M
Puts
$144M
Net Calls
-$2.9M
Net Calls Change
-$54M
Name Holding Trade Value Shares
Change
Change in
Stake
SPPAM
26
Summit Partners Public Asset Management
Massachusetts
$105M -$4.63M -58,673 -4%
Invesco
27
Invesco
Georgia
$95.9M +$637K +8,068 +0.6%
Millennium Management
28
Millennium Management
New York
$79M +$75.6M +958,244 +1,027%
Morgan Stanley
29
Morgan Stanley
New York
$77.1M +$521K +6,603 +0.6%
VFT
30
Vanguard Fiduciary Trust
Pennsylvania
$76.9M +$80.8M +1,024,377 New
Citadel Advisors
31
Citadel Advisors
Florida
$70.8M -$94.1M -1,192,102 -56%
BNP Paribas Asset Management
32
BNP Paribas Asset Management
France
$68.1M -$35.1M -445,304 -33%
Connor, Clark & Lunn Investment Management (CC&L)
33
Connor, Clark & Lunn Investment Management (CC&L)
British Columbia, Canada
$65.6M -$16M -202,281 -19%
Northern Trust
34
Northern Trust
Illinois
$65.2M +$1.69M +21,461 +3%
Bank of America
35
Bank of America
North Carolina
$63.1M +$4.5M +57,019 +7%
PCH
36
Polar Capital Holdings
United Kingdom
$62.3M -$39.8M -503,913 -38%
GAM
37
Groupama Asset Management
France
$61.9M +$4.55M +57,651 +8%
UBS Group
38
UBS Group
Switzerland
$60.7M -$18.7M -236,598 -23%
NAMI
39
Nomura Asset Management International
Pennsylvania
$59M -$6.28M -79,611 -9%
GKIM
40
GW&K Investment Management
Massachusetts
$58.5M -$578K -7,319 -0.9%
Arrowstreet Capital
41
Arrowstreet Capital
Massachusetts
$55.4M -$25.7M -325,468 -31%
Squarepoint
42
Squarepoint
New York
$52.2M +$20.4M +258,997 +59%
Voloridge Investment Management
43
Voloridge Investment Management
Florida
$50.5M +$6.94M +87,888 +15%
Massachusetts Financial Services
44
Massachusetts Financial Services
Massachusetts
$50M -$11.6M -146,631 -18%
Ameriprise
45
Ameriprise
Minnesota
$49.6M +$4.85M +61,396 +10%
N
46
Nuveen
North Carolina
$48.7M -$969K -12,273 -2%
EP
47
Eversept Partners
New York
$47.5M +$7.41M +93,882 +17%
EAM
48
Eventide Asset Management
Massachusetts
$43.2M
TD Asset Management
49
TD Asset Management
Ontario, Canada
$39.8M -$19.2M -243,230 -31%
Teacher Retirement System of Texas
50
Teacher Retirement System of Texas
Texas
$39.3M +$7.97M +101,033 +24%