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Ionis Pharmaceuticals
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Overview Fund Activity

336 hedge funds and large institutions have $4.92B invested in Ionis Pharmaceuticals in 2022 Q4 according to their latest regulatory filings, with 50 funds opening new positions, 114 increasing their positions, 107 reducing their positions, and 52 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
336
Holders Change
-9
Holders Change %
-2.61%
% of All Funds
5.42%
Holding in Top 10
4
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-20%
% of All Funds
0.06%
New
50
Increased
114
Reduced
107
Closed
52
Calls
$15.2M
Puts
$12.8M
Net Calls
+$2.47M
Net Calls Change
-$7.76M

Top Buyers

1
O
OrbiMed
New York
$75.3M
2
DTC
Deep Track Capital
Connecticut
$45.5M
3
TBC
Tweedy, Browne Co
Connecticut
$134M
4
Vanguard Group
Vanguard Group
Pennsylvania
$512M
5
Macquarie Group
Macquarie Group
Australia
$56.3M

Top Sellers

1
BI
BVF Inc
California
$42.4M
2
AIM
ARK Investment Management
Florida
$101M
3
T. Rowe Price Associates
T. Rowe Price Associates
Maryland
$162M
4
WP
Woodline Partners
California
$0
5
Goldman Sachs
Goldman Sachs
New York
$34.8M
Name Holding Trade Value Shares
Change 		Shares
Change %
TD Asset Management
26
TD Asset Management
Ontario, Canada
$29.4M -$929K -24,588 -3%
Jacobs Levy Equity Management
27
Jacobs Levy Equity Management
New Jersey
$26.1M +$6.71M +177,746 +35%
Northern Trust
28
Northern Trust
Illinois
$24.2M +$606K +16,049 +3%
Bank of America
29
Bank of America
North Carolina
$24.1M +$2.92M +77,357 +14%
Two Sigma Advisers
30
Two Sigma Advisers
New York
$24M -$854K -22,600 -3%
Wells Fargo
31
Wells Fargo
California
$23M -$3.09M -81,832 -12%
Bank of New York Mellon
32
Bank of New York Mellon
New York
$21.7M -$212K -5,615 -1%
Axa
33
Axa
France
$19.7M +$12.8M +339,214 +186%
Barclays
34
Barclays
United Kingdom
$19.2M +$107K +2,823 +0.6%
Royal Bank of Canada
35
Royal Bank of Canada
Ontario, Canada
$19.1M +$2.64M +70,021 +16%
PA
36
Pinnacle Associates
New York
$18.7M -$232K -6,140 -1%
Allspring Global Investments
37
Allspring Global Investments
North Carolina
$18.4M +$18.2M +481,018 +6,828%
CS
38
Candriam SCA
Luxembourg
$17.6M +$542K +14,349 +3%
Assenagon Asset Management
39
Assenagon Asset Management
Luxembourg
$16.7M -$414K -10,958 -2%
Nomura Holdings
40
Nomura Holdings
Japan
$15.1M +$459K +12,149 +3%
Citadel Advisors
41
Citadel Advisors
Florida
$14.9M -$857K -22,686 -5%
PAMS
42
Pictet Asset Management (Switzerland)
Switzerland
$14.1M +$3.65M +96,609 +35%
Sumitomo Mitsui Trust Group
43
Sumitomo Mitsui Trust Group
Japan
$12.7M -$3.79M -100,444 -23%
NAMA
44
Nikko Asset Management Americas
New York
$12.7M -$3.79M -100,444 -23%
Baillie Gifford & Co
45
Baillie Gifford & Co
United Kingdom
$12.6M +$338K +8,946 +3%
Qube Research & Technologies (QRT)
46
Qube Research & Technologies (QRT)
United Kingdom
$12.5M +$12M +319,027 +2,727%
California Public Employees Retirement System
47
California Public Employees Retirement System
California
$12.5M +$236K +6,251 +2%
Nuveen Asset Management
48
Nuveen Asset Management
Illinois
$12.2M -$608K -16,106 -5%
Invesco
49
Invesco
Georgia
$12.2M +$1.03M +27,248 +9%
AGA
50
Altrinsic Global Advisors
Connecticut
$12.1M +$5.96M +157,928 +98%
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