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Ionis Pharmaceuticals

338 hedge funds and large institutions have $4.92B invested in Ionis Pharmaceuticals in 2022 Q4 according to their latest regulatory filings, with 50 funds opening new positions, 115 increasing their positions, 107 reducing their positions, and 54 closing their positions.

New
Increased
Maintained
Reduced
Closed

19% more call options, than puts

Call options by funds: $15.2M | Put options by funds: $12.8M

2.93% more ownership

Funds ownership: 89.04%91.97% (+2.9%)

7% more repeat investments, than reductions

Existing positions increased: 115 | Existing positions reduced: 107

7% less first-time investments, than exits

New positions opened: 50 | Existing positions closed: 54

3% less funds holding

Funds holding: 349338 (-11)

11% less capital invested

Capital invested by funds: $5.53B → $4.92B (-$618M)

20% less funds holding in top 10

Funds holding in top 10: 54 (-1)

Holders
338
Holders Change
-11
Holders Change %
-3.15%
% of All Funds
5.43%
Holding in Top 10
4
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-20%
% of All Funds
0.06%
New
50
Increased
115
Reduced
107
Closed
54
Calls
$15.2M
Puts
$12.8M
Net Calls
+$2.46M
Net Calls Change
-$7.76M
Name Holding Trade Value Shares
Change
Change in
Stake
TD Asset Management
26
TD Asset Management
Ontario, Canada
$29.4M -$1.03M -24,588 -3%
Jacobs Levy Equity Management
27
Jacobs Levy Equity Management
New Jersey
$26.1M +$7.48M +177,746 +35%
Northern Trust
28
Northern Trust
Illinois
$24.2M +$675K +16,049 +3%
Bank of America
29
Bank of America
North Carolina
$24.1M +$3.25M +77,357 +14%
Two Sigma Advisers
30
Two Sigma Advisers
New York
$24M -$951K -22,600 -3%
Wells Fargo
31
Wells Fargo
California
$23M -$3.44M -81,832 -12%
Bank of New York Mellon
32
Bank of New York Mellon
New York
$21.7M -$236K -5,615 -1%
Axa
33
Axa
France
$19.7M +$14.3M +339,214 +186%
Barclays
34
Barclays
United Kingdom
$19.2M +$119K +2,823 +0.6%
Royal Bank of Canada
35
Royal Bank of Canada
Ontario, Canada
$19.1M +$2.95M +70,021 +16%
PA
36
Pinnacle Associates
New York
$18.7M -$258K -6,140 -1%
Allspring Global Investments
37
Allspring Global Investments
North Carolina
$18.4M +$20.2M +481,018 +6,828%
CS
38
Candriam SCA
Luxembourg
$17.6M +$604K +14,349 +3%
Assenagon Asset Management
39
Assenagon Asset Management
Luxembourg
$16.7M -$461K -10,958 -2%
Nomura Holdings
40
Nomura Holdings
Japan
$15.1M +$511K +12,149 +3%
Citadel Advisors
41
Citadel Advisors
Florida
$14.9M -$954K -22,686 -5%
PAMS
42
Pictet Asset Management (Switzerland)
Switzerland
$14.1M +$4.06M +96,609 +35%
Sumitomo Mitsui Trust Group
43
Sumitomo Mitsui Trust Group
Japan
$12.7M -$4.22M -100,444 -23%
NAMA
44
Nikko Asset Management Americas
New York
$12.7M -$4.22M -100,444 -23%
Baillie Gifford & Co
45
Baillie Gifford & Co
United Kingdom
$12.6M +$376K +8,946 +3%
Qube Research & Technologies (QRT)
46
Qube Research & Technologies (QRT)
United Kingdom
$12.5M +$13.4M +319,027 +2,727%
California Public Employees Retirement System
47
California Public Employees Retirement System
California
$12.5M +$263K +6,251 +2%
N
48
Nuveen
North Carolina
$12.2M -$677K -16,106 -5%
Invesco
49
Invesco
Georgia
$12.2M +$1.15M +27,248 +9%
AGA
50
Altrinsic Global Advisors
Connecticut
$12.1M +$6.64M +157,928 +98%

IONS Hedge Fund Activity: Q4 2022 in Review

338 of the 6,221 institutional investors tracked by Wall St. Rank reported a position in Ionis Pharmaceuticals (IONS) for Q4 2022, worth a combined $4.92B — down 11% from $5.53B a quarter earlier.

Sellers outnumbered buyers: 54 funds closed out of IONS and 50 opened new positions — a net loss of 4 holders — while 107 trimmed existing stakes and 115 added.

The largest buyer was OrbiMed, adding an estimated $51.5M. The largest seller was BVF Inc, cutting an estimated $73.7M.

  • 338 institutional investors held Ionis Pharmaceuticals (IONS) as of Q4 2022, down from 349 in Q3 2022.
  • Funds reported $4.92B of Ionis Pharmaceuticals stock for Q4 2022, down 11% quarter-over-quarter.
  • 50 funds opened new Ionis Pharmaceuticals positions in Q4 2022 and 54 closed out, a net change of -4 holders.
  • The largest Ionis Pharmaceuticals buyer in Q4 2022 was OrbiMed, an estimated $51.5M added.
  • The largest Ionis Pharmaceuticals seller in Q4 2022 was BVF Inc, an estimated $73.7M sold.

Based on aggregated 13F filings for Q4 2022.