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Ionis Pharmaceuticals

340 hedge funds and large institutions have $3.75B invested in Ionis Pharmaceuticals in 2021 Q4 according to their latest regulatory filings, with 59 funds opening new positions, 106 increasing their positions, 119 reducing their positions, and 38 closing their positions.

New
Increased
Maintained
Reduced
Closed

100% more funds holding in top 10

Funds holding in top 10: 12 (+1)

55% more first-time investments, than exits

New positions opened: 59 | Existing positions closed: 38

5% more funds holding

Funds holding: 324340 (+16)

1.03% more ownership

Funds ownership: 86.24%87.27% (+1%)

8% less capital invested

Capital invested by funds: $4.08B → $3.75B (-$332M)

11% less repeat investments, than reductions

Existing positions increased: 106 | Existing positions reduced: 119

43% less call options, than puts

Call options by funds: $14.9M | Put options by funds: $26.4M

Holders
340
Holders Change
+16
Holders Change %
+4.94%
% of All Funds
5.23%
Holding in Top 10
2
Holding in Top 10 Change
+1
Holding in Top 10 Change %
+100%
% of All Funds
0.03%
New
59
Increased
106
Reduced
119
Closed
38
Calls
$14.9M
Puts
$26.4M
Net Calls
-$11.5M
Net Calls Change
-$18M
Name Holding Trade Value Shares
Change
Change in
Stake
Sumitomo Mitsui Trust Group
26
Sumitomo Mitsui Trust Group
Japan
$18.4M -$2.51M -79,758 -12%
Bank of Nova Scotia
27
Bank of Nova Scotia
Ontario, Canada
$18.3M +$18.6M +589,568 +4,787%
Two Sigma Investments
28
Two Sigma Investments
New York
$18.1M +$8.84M +280,751 +89%
NAMA
29
Nikko Asset Management Americas
New York
$17.9M -$2.18M -69,399 -10%
Goldman Sachs
30
Goldman Sachs
New York
$17.9M -$395K -12,538 -2%
Bank of New York Mellon
31
Bank of New York Mellon
New York
$16.9M -$126K -3,989 -0.7%
PA
32
Pinnacle Associates
New York
$16.5M -$68.7K -2,182 -0.4%
Two Sigma Advisers
33
Two Sigma Advisers
New York
$15.1M +$2.05M +65,200 +15%
Royal Bank of Canada
34
Royal Bank of Canada
Ontario, Canada
$14.6M -$281K -8,913 -2%
Morgan Stanley
35
Morgan Stanley
New York
$14.1M -$1.04M -33,051 -7%
WP
36
Woodline Partners
California
$12.5M +$189K +5,993 +1%
AGA
37
Altrinsic Global Advisors
Connecticut
$12.2M -$1.43M -45,495 -10%
Dimensional Fund Advisors
38
Dimensional Fund Advisors
Texas
$11.8M +$971K +30,852 +9%
EP
39
Eversept Partners
New York
$11.7M -$2.07M -65,712 -15%
Nomura Holdings
40
Nomura Holdings
Japan
$11.3M -$134K -4,268 -1%
Stifel Financial
41
Stifel Financial
Missouri
$10.9M -$575K -18,271 -5%
IBT
42
International Biotechnology Trust
United Kingdom
$10.8M +$9.77M +310,307 +693%
N
43
Nuveen
North Carolina
$10.7M -$8.72M -277,000 -44%
Barclays
44
Barclays
United Kingdom
$10M -$11.1K -353 -0.1%
SCM
45
Sio Capital Management
New York
$9.82M +$10.2M +322,566 New
Baillie Gifford & Co
46
Baillie Gifford & Co
United Kingdom
$9.61M +$435K +13,817 +5%
BNP Paribas Financial Markets
47
BNP Paribas Financial Markets
France
$9.32M +$8.83M +280,521 +1,090%
Hudson Bay Capital Management
48
Hudson Bay Capital Management
Connecticut
$9.28M +$1.26M +40,000 +15%
DY
49
Dowling & Yahnke
California
$9.2M -$3.15K -100 -0%
N
50
Natixis
France
$9.15M +$9.47M +300,797 New

IONS Hedge Fund Activity: Q4 2021 in Review

340 of the 6,498 institutional investors tracked by Wall St. Rank reported a position in Ionis Pharmaceuticals (IONS) for Q4 2021, worth a combined $3.75B — down 8.1% from $4.08B a quarter earlier.

Buyers outnumbered sellers: 59 funds opened new IONS positions and 38 closed out — a net gain of 21 holders — while 106 added to existing stakes and 119 trimmed.

The largest buyer was Millennium Management, adding an estimated $42.2M. The largest seller was ClearBridge Investments, cutting an estimated $45.5M.

  • 340 institutional investors held Ionis Pharmaceuticals (IONS) as of Q4 2021, up from 324 in Q3 2021.
  • Funds reported $3.75B of Ionis Pharmaceuticals stock for Q4 2021, down 8.1% quarter-over-quarter.
  • 59 funds opened new Ionis Pharmaceuticals positions in Q4 2021 and 38 closed out, a net change of +21 holders.
  • The largest Ionis Pharmaceuticals buyer in Q4 2021 was Millennium Management, an estimated $42.2M added.
  • The largest Ionis Pharmaceuticals seller in Q4 2021 was ClearBridge Investments, an estimated $45.5M sold.

Based on aggregated 13F filings for Q4 2021.