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Ionis Pharmaceuticals

490 hedge funds and large institutions have $13B invested in Ionis Pharmaceuticals in 2026 Q1 according to their latest regulatory filings, with 73 funds opening new positions, 177 increasing their positions, 155 reducing their positions, and 66 closing their positions.

New
Increased
Maintained
Reduced
Closed

more repeat investments, than reductions

Existing positions increased: | Existing positions reduced:

more first-time investments, than exits

New positions opened: | Existing positions closed:

more funds holding in top 10

Funds holding in top 10:

more funds holding

Funds holding:

0.75% less ownership

Funds ownership: 105.2%104.44% (-0.75%)

2% less call options, than puts

Call options by funds: $141M | Put options by funds: $144M

4% less capital invested

Capital invested by funds: $13.5B → $13B (-$517M)

Holders
490
Holders Change
Holders Change %
% of All Funds
Holding in Top 10
14
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
New
Increased
Reduced
Closed
Calls
$141M
Puts
$144M
Net Calls
Net Calls Change

Top Buyers

1 +$255M
2 +$252M
3 +$212M
4
Millennium Management
Millennium Management
New York
+$75.6M
5
Artisan Partners
Artisan Partners
Wisconsin
+$69.2M

Top Sellers

1 -$235M
2 -$233M
3 -$94.1M
4
Nomura Holdings
Nomura Holdings
Japan
-$58M
5
TLP
Tri Locum Partners
New York
-$44.1M
Name Holding Trade Value Shares
Change
Change in
Stake
WA
451
WPG Advisers
Maryland
$5.26K
PWMG
452
Private Wealth Management Group
New Jersey
$4.88K
BIA
453
Bell Investment Advisors
California
$4.58K
FHC
454
First Horizon Corporation
Tennessee
$4.21K
MA
455
MCF Advisors
Kentucky
$3.75K
TCM
456
Triumph Capital Management
Colorado
$3.75K
CA
457
Crewe Advisors
Utah
$3.6K
TWC
458
TD Waterhouse Canada
Ontario, Canada
$3.6K
HI
459
Horizon Investments
North Carolina
$3.6K
S
460
Sachetta
Massachusetts
$3.38K
HFS
461
Hantz Financial Services
Michigan
$3K
HWP
462
Highline Wealth Partners
California
$2.85K
TFA
463
Transamerica Financial Advisors
Florida
$2.48K
CVM
464
Cheviot Value Management
California
$2.1K
IAS
465
IMA Advisory Services
Colorado
$2.1K
BGAI
466
Bruce G. Allen Investments
Colorado
$1.73K
TFM
467
TFC Financial Management
Massachusetts
$1.58K
AP
468
Aspect Partners
Virginia
$1.5K
NB
469
NBT Bank
New York
$1.5K
CH
470
Cromwell Holdings
Wyoming
$1.35K
FFO
471
Fortitude Family Office
Arizona
$1.28K
QWM
472
Quaker Wealth Management
New Jersey
$1.13K
CFM
473
Cornerstone Financial Management
Massachusetts
$1.13K
WA
474
Whipplewood Advisors
Colorado
$1.13K
SC
475
SouthState Corp
Florida
$1.05K