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Ionis Pharmaceuticals

490 hedge funds and large institutions have $13B invested in Ionis Pharmaceuticals in 2026 Q1 according to their latest regulatory filings, with 73 funds opening new positions, 177 increasing their positions, 155 reducing their positions, and 66 closing their positions.

New
Increased
Maintained
Reduced
Closed

more repeat investments, than reductions

Existing positions increased: | Existing positions reduced:

more first-time investments, than exits

New positions opened: | Existing positions closed:

more funds holding in top 10

Funds holding in top 10:

more funds holding

Funds holding:

0.75% less ownership

Funds ownership: 105.2%104.44% (-0.75%)

2% less call options, than puts

Call options by funds: $141M | Put options by funds: $144M

4% less capital invested

Capital invested by funds: $13.5B → $13B (-$517M)

Holders
490
Holders Change
Holders Change %
% of All Funds
Holding in Top 10
14
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
New
Increased
Reduced
Closed
Calls
$141M
Puts
$144M
Net Calls
Net Calls Change

Top Buyers

1 +$255M
2 +$252M
3 +$212M
4
Millennium Management
Millennium Management
New York
+$75.6M
5
Artisan Partners
Artisan Partners
Wisconsin
+$69.2M

Top Sellers

1 -$235M
2 -$233M
3 -$94.1M
4
Nomura Holdings
Nomura Holdings
Japan
-$58M
5
TLP
Tri Locum Partners
New York
-$44.1M
Name Holding Trade Value Shares
Change
Change in
Stake
EFMH
426
E Fund Management (HK)
Hong Kong
$14.6K
C
427
Covestor
United Kingdom
$14K
ZBNA
428
Zions Bancorporation, National Association
Utah
$13.3K
OCWP
429
Owl Creek Wealth Partners
Colorado
$12.8K
Fidelity International
430
Fidelity International
Bermuda
$12.4K
SS
431
SBI Securities
Japan
$12.1K
UFPG
432
United Financial Planning Group
New York
$11.9K
MAM
433
Meeder Asset Management
Ohio
$11.4K
SWP
434
Strategic Wealth Partners
Ohio
$11.3K
WPA
435
Wealth Preservation Advisors
Tennessee
$11.3K
MPWT
436
MassMutual Private Wealth & Trust
Connecticut
$10.7K
GXJ
437
Global X Japan
Japan
$9.61K
SWM
438
Spire Wealth Management
Virginia
$9.39K
BWL
439
Bogart Wealth LLC
Virginia
$9.24K
LI
440
LRI Investments
Florida
$8.26K
DB
441
Danske Bank
Denmark
$7.51K
MSG
442
Main Street Group
Virginia
$7.51K
QC
443
Quent Capital
New York
$7.43K
Bessemer Group
444
Bessemer Group
New Jersey
$7K
KFAS
445
Keating Financial Advisory Services
Kansas
$6.76K
TPCW
446
TD Private Client Wealth
New York
$6.01K
OCM
447
Orion Capital Management
California
$6.01K
RF
448
Rossby Financial
Florida
$5.56K
LSA
449
Leonteq Securities AG
Switzerland
$5.48K
CIR
450
Clear Investment Research
Georgia
$5.33K