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Ionis Pharmaceuticals

493 hedge funds and large institutions have $13B invested in Ionis Pharmaceuticals in 2026 Q1 according to their latest regulatory filings, with 74 funds opening new positions, 177 increasing their positions, 156 reducing their positions, and 65 closing their positions.

New
Increased
Maintained
Reduced
Closed

14% more first-time investments, than exits

New positions opened: 74 | Existing positions closed: 65

13% more repeat investments, than reductions

Existing positions increased: 177 | Existing positions reduced: 156

8% more funds holding in top 10

Funds holding in top 10: 1314 (+1)

0% more funds holding

Funds holding: 491493 (+2)

0.72% less ownership

Funds ownership: 105.2%104.48% (-0.72%)

2% less call options, than puts

Call options by funds: $141M | Put options by funds: $144M

4% less capital invested

Capital invested by funds: $13.5B → $13B (-$512M)

Holders
493
Holders Change
+2
Holders Change %
+0.41%
% of All Funds
6.07%
Holding in Top 10
14
Holding in Top 10 Change
+1
Holding in Top 10 Change %
+7.69%
% of All Funds
0.17%
New
74
Increased
177
Reduced
156
Closed
65
Calls
$141M
Puts
$144M
Net Calls
-$2.9M
Net Calls Change
-$54M
Name Holding Trade Value Shares
Change
Change in
Stake
CC
301
Cypress Capital
Tennessee
$451K -$316K -4,000 -40%
FRA
302
Frank Rimerman Advisors
California
$434K
TE
303
Tema ETFs
New York
$426K -$228K -2,884 -34%
Robeco Institutional Asset Management
304
Robeco Institutional Asset Management
Netherlands
$425K +$447K +5,660 New
CCM
305
Coldstream Capital Management
Washington
$424K -$76.2K -966 -15%
CG
306
Cynosure Group
Utah
$422K +$443K +5,614 New
MFIM
307
Mesirow Financial Investment Management
Illinois
$410K +$431K +5,460 New
OIA
308
OneDigital Investment Advisors
Kansas
$405K +$30.3K +384 +8%
GIP
309
Granite Investment Partners
California
$401K +$42.5K +539 +11%
VF
310
Virtu Financial
New York
$401K +$422K +5,342 New
Vontobel Holding
311
Vontobel Holding
Switzerland
$393K
AI
312
Atria Investments
North Carolina
$392K -$33.8K -428 -8%
US Bancorp
313
US Bancorp
Minnesota
$379K -$7.42K -94 -2%
CIBC Asset Management
314
CIBC Asset Management
Ontario, Canada
$377K
CAPTRUST Financial Advisors
315
CAPTRUST Financial Advisors
North Carolina
$375K -$23.1K -293 -6%
MFT
316
Moisand Fitzgerald Tamayo
Florida
$375K
LIP
317
Lighthouse Investment Partners
Florida
$373K -$640K -8,112 -62%
FCM
318
Farallon Capital Management
California
$360K
NA
319
NewEdge Advisors
Louisiana
$359K -$12K -152 -3%
NDSIB
320
North Dakota State Investment Board
North Dakota
$347K -$67.6K -857 -16%
VT
321
Vise Technologies
New York
$341K
TRCT
322
Tower Research Capital (TRC)
New York
$335K +$94.9K +1,203 +37%
CCA
323
Checchi Capital Advisers
California
$333K +$12.4K +157 +4%
Credit Agricole
324
Credit Agricole
France
$331K
KAS
325
Kestra Advisory Services
Texas
$328K -$6.24K -79 -2%