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Ionis Pharmaceuticals

493 hedge funds and large institutions have $13B invested in Ionis Pharmaceuticals in 2026 Q1 according to their latest regulatory filings, with 74 funds opening new positions, 177 increasing their positions, 156 reducing their positions, and 65 closing their positions.

New
Increased
Maintained
Reduced
Closed

14% more first-time investments, than exits

New positions opened: 74 | Existing positions closed: 65

13% more repeat investments, than reductions

Existing positions increased: 177 | Existing positions reduced: 156

8% more funds holding in top 10

Funds holding in top 10: 1314 (+1)

0% more funds holding

Funds holding: 491493 (+2)

0.72% less ownership

Funds ownership: 105.2%104.48% (-0.72%)

2% less call options, than puts

Call options by funds: $141M | Put options by funds: $144M

4% less capital invested

Capital invested by funds: $13.5B → $13B (-$512M)

Holders
493
Holders Change
+2
Holders Change %
+0.41%
% of All Funds
6.07%
Holding in Top 10
14
Holding in Top 10 Change
+1
Holding in Top 10 Change %
+7.69%
% of All Funds
0.17%
New
74
Increased
177
Reduced
156
Closed
65
Calls
$141M
Puts
$144M
Net Calls
-$2.9M
Net Calls Change
-$54M
Name Holding Trade Value Shares
Change
Change in
Stake
SC
276
Savant Capital
Illinois
$635K +$100K +1,272 +18%
DO
277
denkapparat Operations
Germany
$628K
URS
278
Utah Retirement Systems
Utah
$623K
SAM
279
Sectoral Asset Management
Quebec, Canada
$617K -$91.9K -1,165 -14%
CB
280
Commerce Bank
Missouri
$613K +$4.26K +54 +0.7%
Commonwealth Equity Services
281
Commonwealth Equity Services
Massachusetts
$588K -$314K -3,977 -34%
SWP
282
Stratos Wealth Partners
Ohio
$579K -$1.97K -25 -0.3%
OSAM
283
O'Shaughnessy Asset Management
Connecticut
$577K +$51.7K +655 +9%
Cerity Partners
284
Cerity Partners
New York
$570K -$1.29M -16,331 -68%
FT
285
Fiduciary Trust
Massachusetts
$556K
ProShare Advisors
286
ProShare Advisors
Maryland
$555K +$18.6K +236 +3%
MSRPS
287
Maryland State Retirement & Pension System
Maryland
$554K -$71.3K -904 -11%
GSC
288
Ground Swell Capital
South Carolina
$547K +$575K +7,285 New
MAS
289
Meeder Advisory Services
Ohio
$544K +$6.55K +83 +1%
M&T Bank
290
M&T Bank
New York
$540K -$75.1K -952 -12%
CFO
291
Callan Family Office
Pennsylvania
$532K -$1.74K -22 -0.3%
SAM
292
Silvercrest Asset Management
New York
$530K -$14.9K -189 -3%
Principal Financial Group
293
Principal Financial Group
Iowa
$527K +$290K +3,680 +110%
PR
294
PSP Research
Pennsylvania
$511K
SWP
295
Significant Wealth Partners
Illinois
$500K -$7.89K -100 -1%
WPC
296
Wedmont Private Capital
Pennsylvania
$492K +$81.1K +1,028 +19%
JSSH
297
J. Safra Sarasin Holding
$483K -$866K -10,973 -63%
Mercer Global Advisors
298
Mercer Global Advisors
Colorado
$473K +$58.6K +742 +13%
ECM
299
Everence Capital Management
Indiana
$468K -$42.5K -538 -8%
RFC
300
Regions Financial Corp
Alabama
$460K +$2.6K +33 +0.5%