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Ionis Pharmaceuticals

339 hedge funds and large institutions have $5.01B invested in Ionis Pharmaceuticals in 2025 Q1 according to their latest regulatory filings, with 54 funds opening new positions, 102 increasing their positions, 122 reducing their positions, and 61 closing their positions.

New
Increased
Maintained
Reduced
Closed

more funds holding in top 10

Funds holding in top 10:

more call options, than puts

Call options by funds: $ | Put options by funds: $

more ownership

Funds ownership:

less funds holding

Funds holding:

11% less capital invested

Capital invested by funds: $5.61B → $5.01B (-$606M)

11% less first-time investments, than exits

New positions opened: 54 | Existing positions closed: 61

16% less repeat investments, than reductions

Existing positions increased: 102 | Existing positions reduced: 122

Holders
339
Holders Change
Holders Change %
% of All Funds
Holding in Top 10
6
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
New
Increased
Reduced
Closed
Calls
$24.8M
Puts
$18.8M
Net Calls
Net Calls Change

Top Buyers

1 +$79.4M
2 +$60.5M
3 +$57.7M
4
Citadel Advisors
Citadel Advisors
Florida
+$39.6M
5
Fidelity Investments
Fidelity Investments
Massachusetts
+$27.9M
Name Holding Trade Value Shares
Change
Change in
Stake
NA
251
NewEdge Advisors
Louisiana
$48.9K
TLCM
252
Twin Lakes Capital Management
California
$45.3K
IA
253
IFP Advisors
Florida
$42.4K
S
254
SignatureFD
Georgia
$41.7K
Comerica Bank
255
Comerica Bank
Texas
$39.8K
MCM
256
Manchester Capital Management
Vermont
$37.7K
EWA
257
EverSource Wealth Advisors
Alabama
$34.9K
IUHSA
258
Itau Unibanco Holding S.A.
Brazil
$34K
SCM
259
Sterling Capital Management
North Carolina
$33.2K
HNB
260
Huntington National Bank
Ohio
$33K
SPIA
261
Steward Partners Investment Advisory
New York
$32.9K
SS
262
Sunbelt Securities
Texas
$30.6K
GI
263
GAMMA Investing
California
$29K
HI
264
Harbour Investments
Wisconsin
$27.2K
PA
265
Parallel Advisors
California
$22.5K
A
266
AlphaQuest
New York
$19.2K
LWANC
267
Laurel Wealth Advisors (North Carolina)
North Carolina
$18.1K
AIC
268
Archer Investment Corporation
Indiana
$18.1K
RTC
269
Riverview Trust Company
Washington
$14.4K
LC
270
Lindbrook Capital
California
$13.3K
FFA
271
Farther Finance Advisors
California
$12.9K
MG
272
Mather Group
Illinois
$12.4K
GTAM
273
Global Trust Asset Management
Florida
$12K
QCG
274
Quadrant Capital Group
Ohio
$11.5K
PFBT
275
Parkside Financial Bank & Trust
Missouri
$11.4K