511 hedge funds and large institutions have $21.1B invested in Insmed in 2025 Q2 according to their latest regulatory filings, with 132 funds opening new positions, 161 increasing their positions, 188 reducing their positions, and 52 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
511
Holders Change
+76
Holders Change %
+17.47%
% of All Funds
6.85%
Holding in Top 10
33
Holding in Top 10 Change
+2
Holding in Top 10 Change %
+6.45%
% of All Funds
0.44%
New
132
Increased
161
Reduced
188
Closed
52
Calls
$300M
Puts
$356M
Net Calls
-$56.3M
Net Calls Change
+$15.7M
Name Holding Trade Value Shares
Change
Shares
Change %
DGM
1
Darwin Global Management
Jersey
$1.92B +$393M +3,946,646 +26%
Vanguard Group
2
Vanguard Group
Pennsylvania
$1.78B -$62.8M -623,630 -3%
JPMorgan Chase & Co
3
JPMorgan Chase & Co
New York
$1.57B +$934M +9,282,377 +146%
T. Rowe Price Associates
4
T. Rowe Price Associates
Maryland
$1.13B -$170M -1,692,836 -13%
BlackRock
5
BlackRock
New York
$1.12B -$494M -4,906,450 -31%
BBA
6
Baker Bros. Advisors
New York
$776M +$235M +2,332,274 +43%
Capital International Investors
7
Capital International Investors
California
$753M +$28.2M +280,374 +4%
Fidelity Investments
8
Fidelity Investments
Massachusetts
$513M +$171M +1,698,877 +50%
State Street
9
State Street
Massachusetts
$431M -$148M -1,469,405 -26%
D.E. Shaw & Co
10
D.E. Shaw & Co
New York
$344M +$270M +2,687,739 +366%
Geode Capital Management
11
Geode Capital Management
Massachusetts
$336M -$95.4M -948,028 -22%
Artisan Partners
12
Artisan Partners
Wisconsin
$334M +$9.77M +97,073 +3%
RI
13
RTW Investments
New York
$310M +$7.04M +70,000 +2%
Ameriprise
14
Ameriprise
Minnesota
$298M +$639K +6,351 +0.2%
Adage Capital Partners
15
Adage Capital Partners
Massachusetts
$288M -$59.1M -587,492 -17%
Franklin Resources
16
Franklin Resources
California
$237M +$20.3M +201,849 +9%
Janus Henderson Group
17
Janus Henderson Group
United Kingdom
$231M +$75.2M +747,723 +48%
DFO
18
Duquesne Family Office
New York
$227M +$89M +884,385 +65%
Millennium Management
19
Millennium Management
New York
$214M +$145M +1,442,526 +212%
Holocene Advisors
20
Holocene Advisors
New York
$203M -$968K -9,616 -0.5%
Norges Bank
21
Norges Bank
Norway
$195M +$195M +1,934,899 New
Invesco
22
Invesco
Georgia
$191M +$10.6M +105,009 +6%
Goldman Sachs
23
Goldman Sachs
New York
$182M +$41.1M +408,274 +29%
DTC
24
Deep Track Capital
Connecticut
$176M +$150M +1,495,249 +587%
William Blair Investment Management
25
William Blair Investment Management
Illinois
$168M -$65.2M -647,615 -28%