We are live on ! Find out more

516 hedge funds and large institutions have $21.2B invested in Insmed in 2025 Q2 according to their latest regulatory filings, with 131 funds opening new positions, 165 increasing their positions, 189 reducing their positions, and 52 closing their positions.

New
Increased
Maintained
Reduced
Closed

152% more first-time investments, than exits

New positions opened: 131 | Existing positions closed: 52

38% more capital invested

Capital invested by funds: $15.3B → $21.2B (+$5.85B)

17% more funds holding

Funds holding: 441516 (+75)

6% more funds holding in top 10

Funds holding in top 10: 3133 (+2)

5.23% more ownership

Funds ownership: 110.29%115.51% (+5.2%)

13% less repeat investments, than reductions

Existing positions increased: 165 | Existing positions reduced: 189

16% less call options, than puts

Call options by funds: $300M | Put options by funds: $356M

Holders
516
Holders Change
+75
Holders Change %
+17.01%
% of All Funds
6.79%
Holding in Top 10
33
Holding in Top 10 Change
+2
Holding in Top 10 Change %
+6.45%
% of All Funds
0.43%
New
131
Increased
165
Reduced
189
Closed
52
Calls
$300M
Puts
$356M
Net Calls
-$56.3M
Net Calls Change
+$15.7M
Name Holding Trade Value Shares
Change
Change in
Stake
DGM
1
Darwin Global Management
Jersey
$1.92B +$302M +3,946,646 +26%
Vanguard Group
2
Vanguard Group
Pennsylvania
$1.78B -$47.7M -623,630 -3%
JP Morgan Chase
3
JP Morgan Chase
New York
$1.57B +$710M +9,282,377 +146%
T. Rowe Price Associates
4
T. Rowe Price Associates
Maryland
$1.13B -$129M -1,692,836 -13%
BlackRock
5
BlackRock
New York
$1.12B -$375M -4,906,450 -31%
BBA
6
Baker Bros. Advisors
New York
$776M +$178M +2,332,274 +43%
Capital International Investors
7
Capital International Investors
California
$753M +$21.4M +280,374 +4%
Fidelity Investments
8
Fidelity Investments
Massachusetts
$513M +$130M +1,698,877 +50%
State Street
9
State Street
Massachusetts
$431M -$112M -1,469,405 -26%
D.E. Shaw & Co
10
D.E. Shaw & Co
New York
$344M +$206M +2,687,739 +366%
Geode Capital Management
11
Geode Capital Management
Massachusetts
$336M -$72.5M -948,028 -22%
Artisan Partners
12
Artisan Partners
Wisconsin
$334M +$7.42M +97,073 +3%
RI
13
RTW Investments
New York
$310M +$5.35M +70,000 +2%
Ameriprise
14
Ameriprise
Minnesota
$298M +$486K +6,351 +0.2%
Adage Capital Partners
15
Adage Capital Partners
Massachusetts
$288M -$44.9M -587,492 -17%
Franklin Resources
16
Franklin Resources
California
$237M +$15.4M +201,849 +9%
Janus Henderson Group
17
Janus Henderson Group
United Kingdom
$231M +$57.2M +747,723 +48%
DFO
18
Duquesne Family Office
New York
$227M +$67.6M +884,385 +65%
Millennium Management
19
Millennium Management
New York
$214M +$110M +1,442,526 +212%
Holocene Advisors
20
Holocene Advisors
New York
$203M -$735K -9,616 -0.5%
Norges Bank
21
Norges Bank
Norway
$195M +$14.7M +192,056 +11%
Invesco
22
Invesco
Georgia
$191M +$8.03M +105,009 +6%
Goldman Sachs
23
Goldman Sachs
New York
$182M +$31.2M +408,274 +29%
DTC
24
Deep Track Capital
Connecticut
$176M +$114M +1,495,249 +587%
William Blair Investment Management
25
William Blair Investment Management
Illinois
$168M -$49.5M -647,615 -28%

INSM Hedge Fund Activity: Q2 2025 in Review

516 of the 7,595 institutional investors tracked by Wall St. Rank reported a position in Insmed (INSM) for Q2 2025, worth a combined $21.2B — up 38% from $15.3B a quarter earlier.

Buyers outnumbered sellers: 131 funds opened new INSM positions and 52 closed out — a net gain of 79 holders — while 165 added to existing stakes and 189 trimmed.

The largest buyer was JP Morgan Chase, adding an estimated $710M. The largest seller was BlackRock, cutting an estimated $375M.

  • 516 institutional investors held Insmed (INSM) as of Q2 2025, up from 441 in Q1 2025.
  • Funds reported $21.2B of Insmed stock for Q2 2025, up 38% quarter-over-quarter.
  • 131 funds opened new Insmed positions in Q2 2025 and 52 closed out, a net change of +79 holders.
  • The largest Insmed buyer in Q2 2025 was JP Morgan Chase, an estimated $710M added.
  • The largest Insmed seller in Q2 2025 was BlackRock, an estimated $375M sold.

Based on aggregated 13F filings for Q2 2025.