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669 hedge funds and large institutions have $35B invested in Insmed in 2026 Q1 according to their latest regulatory filings, with 98 funds opening new positions, 288 increasing their positions, 214 reducing their positions, and 93 closing their positions.

New
Increased
Maintained
Reduced
Closed

52% more call options, than puts

Call options by funds: $352M | Put options by funds: $232M

35% more repeat investments, than reductions

Existing positions increased: 288 | Existing positions reduced: 214

18% more funds holding in top 10

Funds holding in top 10: 2226 (+4)

5% more first-time investments, than exits

New positions opened: 98 | Existing positions closed: 93

0.72% more ownership

Funds ownership: 99.68%100.4% (+0.72%)

1% less funds holding

Funds holding: 676669 (-7)

6% less capital invested

Capital invested by funds: $37B → $35B (-$2.04B)

Holders
669
Holders Change
-7
Holders Change %
-1.04%
% of All Funds
8.24%
Holding in Top 10
26
Holding in Top 10 Change
+4
Holding in Top 10 Change %
+18.18%
% of All Funds
0.32%
New
98
Increased
288
Reduced
214
Closed
93
Calls
$352M
Puts
$232M
Net Calls
+$120M
Net Calls Change
+$191M
Name Holding Trade Value Shares
Change
Change in
Stake
JP Morgan Chase
1
JP Morgan Chase
New York
$3.7B +$146M +950,987 +4%
BlackRock
2
BlackRock
New York
$2.73B +$248M +1,613,094 +11%
DGM
3
Darwin Global Management
Jersey
$2.58B -$635M -4,128,093 -20%
Fidelity Investments
4
Fidelity Investments
Massachusetts
$2.15B +$497M +3,232,231 +33%
VPM
5
Vanguard Portfolio Management
Pennsylvania
$1.7B +$1.59B +10,371,802 New
VCM
6
Vanguard Capital Management
Pennsylvania
$1.58B +$1.48B +9,642,131 New
BBA
7
Baker Bros. Advisors
New York
$1.21B +$127M +828,365 +13%
Artisan Partners
8
Artisan Partners
Wisconsin
$1.07B +$259M +1,683,552 +35%
D.E. Shaw & Co
9
D.E. Shaw & Co
New York
$920M +$196M +1,274,830 +29%
Capital International Investors
10
Capital International Investors
California
$915M +$68.2M +443,523 +9%
State Street
11
State Street
Massachusetts
$908M +$53.8M +349,955 +7%
RI
12
RTW Investments
New York
$792M +$154 +1 +0%
Geode Capital Management
13
Geode Capital Management
Massachusetts
$733M +$23.3M +151,337 +4%
T. Rowe Price Associates
14
T. Rowe Price Associates
Maryland
$506M -$146M -946,659 -23%
Ameriprise
15
Ameriprise
Minnesota
$500M +$167M +1,088,861 +55%
Franklin Resources
16
Franklin Resources
California
$428M -$21.3M -138,285 -5%
Citadel Advisors
17
Citadel Advisors
Florida
$357M +$158M +1,025,276 +89%
Invesco
18
Invesco
Georgia
$325M -$113M -737,889 -27%
OAG
19
Orbis Allan Gray
Bermuda
$306M -$355M -2,307,133 -55%
UBS Group
20
UBS Group
Switzerland
$284M -$20M -130,154 -7%
Bank of America
21
Bank of America
North Carolina
$246M -$34.3M -223,400 -13%
IHAM
22
Integral Health Asset Management
New York
$245M +$38.4M +250,000 +20%
Westfield Capital Management
23
Westfield Capital Management
Massachusetts
$240M +$159M +1,035,938 +240%
SEI Investments
24
SEI Investments
Pennsylvania
$228M +$77.7M +505,624 +57%
Capital World Investors
25
Capital World Investors
California
$223M +$209M +1,362,291 New