D.E. Shaw & Co’s Insmed INSM Stock Holding History

Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake
Trade Value Portfolio Weight Portfolio Position
2026
Q1
$920M Buy
5,625,825
+1,274,830
+29% +$196M 0.55% 17
2025
Q4
$757M Sell
4,350,995
-1,306,469
-23% -$238M 0.42% 27
2025
Q3
$815M Buy
5,657,464
+2,234,845
+65% +$274M 0.46% 23
2025
Q2
$344M Buy
3,422,619
+2,687,739
+366% +$206M 0.24% 70
2025
Q1
$56.1M Buy
734,880
+226,093
+44% +$17.3M 0.05% 438
2024
Q4
$35.1M Buy
508,787
+442,052
+662% +$31.8M 0.03% 728
2024
Q3
$4.87M Sell
66,735
-221,816
-77% -$16.4M ﹤0.01% 1977
2024
Q2
$19.3M Buy
288,551
+114,529
+66% +$4.44M 0.02% 915
2024
Q1
$4.72M Sell
174,022
-472,885
-73% -$13.2M ﹤0.01% 1928
2023
Q4
$20M Buy
646,907
+450,180
+229% +$11.7M 0.02% 920
2023
Q3
$4.97M Buy
196,727
+97,823
+99% +$2.24M 0.01% 1814
2023
Q2
$2.09M Sell
98,904
-138,463
-58% -$2.63M ﹤0.01% 2597
2023
Q1
$4.05M Sell
237,367
-189,916
-44% -$3.69M ﹤0.01% 2124
2022
Q4
$8.54M Sell
427,283
-209,710
-33% -$4.05M 0.01% 1579
2022
Q3
$13.7M Buy
636,993
+262,347
+70% +$6.29M 0.02% 1107
2022
Q2
$7.39M Buy
374,646
+78,653
+27% +$1.65M 0.01% 1696
2022
Q1
$6.96M Sell
295,993
-7,737
-3% -$180K 0.01% 1961
2021
Q4
$8.27M Sell
303,730
-60,254
-17% -$1.72M 0.01% 1848
2021
Q3
$10M Sell
363,984
-59,162
-14% -$1.55M 0.01% 1521
2021
Q2
$12M Sell
423,146
-326,663
-44% -$9.69M 0.01% 1344
2021
Q1
$25.5M Sell
749,809
-252,688
-25% -$9.66M 0.02% 800
2020
Q4
$33.4M Sell
1,002,497
-612,553
-38% -$22.4M 0.03% 683
2020
Q3
$51.9M Sell
1,615,050
-132,657
-8% -$3.81M 0.05% 407
2020
Q2
$48.1M Sell
1,747,707
-489,141
-22% -$11.6M 0.06% 366
2020
Q1
$35.9M Sell
2,236,848
-754,627
-25% -$17.9M 0.06% 380
2019
Q4
$71.4M Buy
2,991,475
+430,169
+17% +$8.75M 0.08% 291
2019
Q3
$45.2M Buy
2,561,306
+342,359
+15% +$6.61M 0.06% 411
2019
Q2
$56.8M Buy
2,218,947
+1,625,381
+274% +$45.3M 0.07% 335
2019
Q1
$17.3M Buy
593,566
+516,860
+674% +$13.4M 0.02% 797
2018
Q4
$1.01M Sell
76,706
-71,409
-48% -$1.14M ﹤0.01% 2656
2018
Q3
$3M Sell
148,115
-221,210
-60% -$5M ﹤0.01% 1926
2018
Q2
$8.73M Buy
369,325
+75,347
+26% +$1.94M 0.01% 1165
2018
Q1
$6.62M Sell
293,978
-213,347
-42% -$5.61M 0.01% 1236
2017
Q4
$15.8M Sell
507,325
-306,237
-38% -$9.05M 0.02% 792
2017
Q3
$25.4M Buy
813,562
+662,332
+438% +$12.6M 0.04% 520
2017
Q2
$2.6M Sell
151,230
-4,775
-3% -$81.6K ﹤0.01% 1809
2017
Q1
$2.73M Buy
156,005
+21,683
+16% +$334K ﹤0.01% 1650
2016
Q4
$1.78M Sell
134,322
-60
-0% -$819 ﹤0.01% 2074
2016
Q3
$1.95M Sell
134,382
-60,876
-31% -$762K ﹤0.01% 1943
2016
Q2
$1.93M Buy
195,258
+72,439
+59% +$845K ﹤0.01% 1964
2016
Q1
$1.56M Sell
122,819
-17,866
-13% -$235K ﹤0.01% 2059
2015
Q4
$2.55M Sell
140,685
-167,327
-54% -$2.95M ﹤0.01% 1935
2015
Q3
$5.72M Buy
308,012
+39,000
+14% +$973K 0.01% 1300
2015
Q2
$6.57M Buy
269,012
+140,437
+109% +$3.19M 0.01% 1281
2015
Q1
$2.67M Sell
128,575
-142,175
-53% -$2.5M ﹤0.01% 1807
2014
Q4
$4.19M Buy
270,750
+245,580
+976% +$3.48M 0.01% 1702
2014
Q3
$328K Sell
25,170
-182,051
-88% -$2.75M ﹤0.01% 3635
2014
Q2
$4.14M Buy
207,221
+130,004
+168% +$1.93M 0.01% 1757
2014
Q1
$1.47M Buy
77,217
+58,138
+305% +$1.1M ﹤0.01% 2682
2013
Q4
$325K Sell
19,079
-9,995
-34% -$153K ﹤0.01% 4009
2013
Q3
$454K Buy
29,074
+10,730
+58% +$136K ﹤0.01% 3645
2013
Q2
$219K Buy
+18,344
New +$188K ﹤0.01% 3720

Other funds holding INSM

D.E. Shaw & Co's INSM Position: Q1 2026 in Review

D.E. Shaw & Co increased its Insmed (INSM) stake by 29% in Q1 2026, buying an estimated $196M and bringing the position to 5,625,825 shares worth $920M. The position accounts for 0.55% of the portfolio, ranked #17.

D.E. Shaw & Co first reported a position in INSM in Q2 2013 and has held it in 52 quarters since. 669 funds tracked by Wall St. Rank hold INSM as of Q1 2026.

  • D.E. Shaw & Co held 5,625,825 shares of Insmed worth $920M as of Q1 2026.
  • D.E. Shaw & Co bought 1,274,830 Insmed shares in Q1 2026, an estimated $196M.
  • Insmed made up 0.55% of D.E. Shaw & Co's portfolio in Q1 2026, its #17 holding.
  • D.E. Shaw & Co first reported a position in Insmed in Q2 2013 and has held it in 52 quarters since.
  • 669 funds tracked by Wall St. Rank held Insmed as of Q1 2026.

Based on D.E. Shaw & Co's 13F filing for Q1 2026, filed 15 May 2026.