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441 hedge funds and large institutions have $15.3B invested in Insmed in 2025 Q1 according to their latest regulatory filings, with 56 funds opening new positions, 185 increasing their positions, 151 reducing their positions, and 48 closing their positions.

New
Increased
Maintained
Reduced
Closed

23% more repeat investments, than reductions

Existing positions increased: 185 | Existing positions reduced: 151

17% more first-time investments, than exits

New positions opened: 56 | Existing positions closed: 48

15% more capital invested

Capital invested by funds: $13.3B → $15.3B (+$2.01B)

7% more funds holding in top 10

Funds holding in top 10: 2931 (+2)

2.65% more ownership

Funds ownership: 107.64%110.29% (+2.7%)

1% more funds holding

Funds holding: 438441 (+3)

50% less call options, than puts

Call options by funds: $73M | Put options by funds: $145M

Holders
441
Holders Change
+3
Holders Change %
+0.68%
% of All Funds
5.91%
Holding in Top 10
31
Holding in Top 10 Change
+2
Holding in Top 10 Change %
+6.9%
% of All Funds
0.42%
New
56
Increased
185
Reduced
151
Closed
48
Calls
$73M
Puts
$145M
Net Calls
-$72M
Net Calls Change
-$110M
Name Holding Trade Value Shares
Change
Change in
Stake
Vanguard Group
1
Vanguard Group
Pennsylvania
$1.39B +$3.76M +49,149 +0.3%
BlackRock
2
BlackRock
New York
$1.22B +$1.22M +15,938 +0.1%
DGM
3
Darwin Global Management
Jersey
$1.2B +$186M +2,437,437 +19%
T. Rowe Price Associates
4
T. Rowe Price Associates
Maryland
$986M +$16.8M +219,131 +2%
Capital International Investors
5
Capital International Investors
California
$549M +$6.23M +81,488 +1%
JP Morgan Chase
6
JP Morgan Chase
New York
$485M +$235M +3,067,774 +93%
State Street
7
State Street
Massachusetts
$438M -$27.5M -358,860 -6%
BBA
8
Baker Bros. Advisors
New York
$410M +$28.6M +373,763 +7%
Geode Capital Management
9
Geode Capital Management
Massachusetts
$327M +$15.4M +201,592 +5%
Adage Capital Partners
10
Adage Capital Partners
Massachusetts
$263M +$138M +1,799,382 +109%
Fidelity Investments
11
Fidelity Investments
Massachusetts
$259M -$112M -1,461,865 -30%
Artisan Partners
12
Artisan Partners
Wisconsin
$245M +$6.96M +90,929 +3%
RI
13
RTW Investments
New York
$230M
Ameriprise
14
Ameriprise
Minnesota
$225M +$7.77M +101,525 +4%
AllianceBernstein
15
AllianceBernstein
Tennessee
$185M +$4.59M +59,952 +3%
Fidelity International
16
Fidelity International
Bermuda
$182M -$19M -247,959 -9%
Macquarie Group
17
Macquarie Group
Australia
$180M +$3.74M +48,946 +2%
William Blair Investment Management
18
William Blair Investment Management
Illinois
$176M -$9.2M -120,226 -5%
Franklin Resources
19
Franklin Resources
California
$164M -$904K -11,819 -0.5%
Holocene Advisors
20
Holocene Advisors
New York
$155M +$102M +1,338,710 +195%
Pictet Asset Management
21
Pictet Asset Management
Switzerland
$154M +$4.1M +53,611 +3%
ClearBridge Investments
22
ClearBridge Investments
New York
$140M -$3.8M -49,722 -3%
Invesco
23
Invesco
Georgia
$137M +$59.3M +775,234 +76%
Principal Financial Group
24
Principal Financial Group
Iowa
$134M -$4.76M -62,270 -3%
Norges Bank
25
Norges Bank
Norway
$133M -$6.96M -90,967 -5%

INSM Hedge Fund Activity: Q1 2025 in Review

441 of the 7,458 institutional investors tracked by Wall St. Rank reported a position in Insmed (INSM) for Q1 2025, worth a combined $15.3B — up 15% from $13.3B a quarter earlier.

Buyers outnumbered sellers: 56 funds opened new INSM positions and 48 closed out — a net gain of 8 holders — while 185 added to existing stakes and 151 trimmed.

The largest buyer was JP Morgan Chase, adding an estimated $235M. The largest seller was Fidelity Investments, cutting an estimated $112M.

  • 441 institutional investors held Insmed (INSM) as of Q1 2025, up from 438 in Q4 2024.
  • Funds reported $15.3B of Insmed stock for Q1 2025, up 15% quarter-over-quarter.
  • 56 funds opened new Insmed positions in Q1 2025 and 48 closed out, a net change of +8 holders.
  • The largest Insmed buyer in Q1 2025 was JP Morgan Chase, an estimated $235M added.
  • The largest Insmed seller in Q1 2025 was Fidelity Investments, an estimated $112M sold.

Based on aggregated 13F filings for Q1 2025.