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663 hedge funds and large institutions have $23.8B invested in Insmed in 2026 Q2 according to their latest regulatory filings, with 119 funds opening new positions, 244 increasing their positions, 230 reducing their positions, and 121 closing their positions.

New
Increased
Maintained
Reduced
Closed

49% more call options, than puts

Call options by funds: $614M | Put options by funds: $411M

6% more repeat investments, than reductions

Existing positions increased: 244 | Existing positions reduced: 230

0.53% more ownership

Funds ownership: 102.5%103.03% (+0.53%)

2% less first-time investments, than exits

New positions opened: 119 | Existing positions closed: 121

1% less funds holding

Funds holding: 673663 (-10)

33% less capital invested

Capital invested by funds: $35.7B → $23.8B (-$11.9B)

38% less funds holding in top 10

Funds holding in top 10: 2616 (-10)

Holders
663
Holders Change
-10
Holders Change %
-1.49%
% of All Funds
8.01%
Holding in Top 10
16
Holding in Top 10 Change
-10
Holding in Top 10 Change %
-38.46%
% of All Funds
0.19%
New
119
Increased
244
Reduced
230
Closed
121
Calls
$614M
Puts
$411M
Net Calls
+$202M
Net Calls Change
+$81.9M
Name Holding Trade Value Shares
Change
Change in
Stake
Fidelity Investments
1
Fidelity Investments
Massachusetts
$1.72B +$361M +2,983,416 +23%
BlackRock
2
BlackRock
New York
$1.69B -$105M -870,162 -5%
Vanguard Portfolio Management
3
Vanguard Portfolio Management
Pennsylvania
$1.11B +$4.38M +36,160 +0.3%
JP Morgan Chase
4
JP Morgan Chase
New York
$1.09B -$1.66B -13,722,329 -57%
Vanguard Capital Management
5
Vanguard Capital Management
Pennsylvania
$1.04B +$18M +148,734 +2%
BBA
6
Baker Bros. Advisors
New York
$938M +$166M +1,375,000 +19%
Capital International Investors
7
Capital International Investors
California
$878M +$320M +2,642,930 +47%
DGM
8
Darwin Global Management
Jersey
$674M -$1.26B -10,374,021 -62%
Ameriprise
9
Ameriprise
Minnesota
$659M +$378M +3,121,853 +102%
OAG
10
Orbis Allan Gray
Bermuda
$648M +$509M +4,203,663 +224%
State Street
11
State Street
Massachusetts
$645M +$60.6M +500,475 +9%
D.E. Shaw & Co
12
D.E. Shaw & Co
New York
$627M +$30.5M +252,134 +4%
Artisan Partners
13
Artisan Partners
Wisconsin
$580M -$131M -1,085,583 -17%
RI
14
RTW Investments
New York
$516M
Geode Capital Management
15
Geode Capital Management
Massachusetts
$449M -$27.9M -230,234 -5%
T. Rowe Price Associates
16
T. Rowe Price Associates
Maryland
$363M +$37.8M +312,483 +10%
Norges Bank
17
Norges Bank
Norway
$360M +$409M +3,377,641 New
JT
18
Jupiter Topco
New York
$278M +$315M +2,605,181 New
UBS Group
19
UBS Group
Switzerland
$276M +$103M +846,965 +49%
Citadel Advisors
20
Citadel Advisors
Florida
$273M +$45.3M +374,402 +17%
Franklin Resources
21
Franklin Resources
California
$242M -$41.7M -344,029 -13%
MC
22
Maverick Capital
Texas
$229M +$260M +2,150,762 New
Millennium Management
23
Millennium Management
New York
$218M +$108M +890,219 +77%
Qube Research & Technologies (QRT)
24
Qube Research & Technologies (QRT)
United Kingdom
$179M +$186M +1,533,819 +1,033%
Westfield Capital Management
25
Westfield Capital Management
Massachusetts
$174M +$19.5M +161,102 +11%

INSM Hedge Fund Activity: Q2 2026 in Review

663 of the 8,279 institutional investors tracked by Wall St. Rank reported a position in Insmed (INSM) for Q2 2026, worth a combined $23.8B — down 33% from $35.7B a quarter earlier.

Sellers outnumbered buyers: 121 funds closed out of INSM and 119 opened new positions — a net loss of 2 holders — while 230 trimmed existing stakes and 244 added.

The largest buyer was Orbis Allan Gray, adding an estimated $509M. The largest seller was JP Morgan Chase, cutting an estimated $1.66B.

  • 663 institutional investors held Insmed (INSM) as of Q2 2026, down from 673 in Q1 2026.
  • Funds reported $23.8B of Insmed stock for Q2 2026, down 33% quarter-over-quarter.
  • 119 funds opened new Insmed positions in Q2 2026 and 121 closed out, a net change of -2 holders.
  • The largest Insmed buyer in Q2 2026 was Orbis Allan Gray, an estimated $509M added.
  • The largest Insmed seller in Q2 2026 was JP Morgan Chase, an estimated $1.66B sold.

Based on aggregated 13F filings for Q2 2026.