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516 hedge funds and large institutions have $21.2B invested in Insmed in 2025 Q2 according to their latest regulatory filings, with 131 funds opening new positions, 165 increasing their positions, 189 reducing their positions, and 52 closing their positions.

New
Increased
Maintained
Reduced
Closed

152% more first-time investments, than exits

New positions opened: 131 | Existing positions closed: 52

38% more capital invested

Capital invested by funds: $15.3B → $21.2B (+$5.85B)

17% more funds holding

Funds holding: 441516 (+75)

6% more funds holding in top 10

Funds holding in top 10: 3133 (+2)

5.23% more ownership

Funds ownership: 110.29%115.51% (+5.2%)

13% less repeat investments, than reductions

Existing positions increased: 165 | Existing positions reduced: 189

16% less call options, than puts

Call options by funds: $300M | Put options by funds: $356M

Holders
516
Holders Change
+75
Holders Change %
+17.01%
% of All Funds
6.79%
Holding in Top 10
33
Holding in Top 10 Change
+2
Holding in Top 10 Change %
+6.45%
% of All Funds
0.43%
New
131
Increased
165
Reduced
189
Closed
52
Calls
$300M
Puts
$356M
Net Calls
-$56.3M
Net Calls Change
+$15.7M
Name Holding Trade Value Shares
Change
Change in
Stake
NYLIM
251
New York Life Investment Management
New York
$1.88M -$9.48K -124 -0.7%
VRS
252
Virginia Retirement Systems
Virginia
$1.83M +$161K +2,100 +13%
Two Sigma Advisers
253
Two Sigma Advisers
New York
$1.76M -$10.7M -139,700 -89%
NICM
254
Neo Ivy Capital Management
New York
$1.74M +$979K +12,804 +288%
BG
255
Bollard Group
Massachusetts
$1.73M +$1.31M +17,191 New
DIA
256
Dana Investment Advisors
Wisconsin
$1.72M -$103K -1,348 -7%
AI
257
Atria Investments
North Carolina
$1.69M +$552K +7,219 +75%
AIM
258
Aigen Investment Management
New York
$1.61M +$1.22M +15,961 New
SAM
259
Simplify Asset Management
Nevada
$1.56M -$389K -5,094 -25%
Corient Private Wealth
260
Corient Private Wealth
Florida
$1.51M +$207K +2,705 +22%
Wolverine Trading
261
Wolverine Trading
Illinois
$1.5M +$1.15M +15,088 New
SAM
262
Sectoral Asset Management
Quebec, Canada
$1.5M -$26.8K -350 -2%
SCM
263
Superstring Capital Management
New York
$1.47M +$1.11M +14,571 New
LCM
264
Laurion Capital Management
New York
$1.44M +$1.1M +14,347 New
Mackenzie Financial
265
Mackenzie Financial
Ontario, Canada
$1.37M +$36.5K +478 +4%
O
266
OrbiMed
New York
$1.35M -$1.16M -15,200 -53%
EA
267
Emerald Advisers
Pennsylvania
$1.33M -$44.4M -580,749 -98%
GAM
268
Groupama Asset Management
France
$1.31M +$1.01M +13,175 New
AB
269
Amalgamated Bank
New York
$1.31M +$535K +7,003 +117%
HSBC Holdings
270
HSBC Holdings
United Kingdom
$1.3M -$648K -8,474 -40%
QIM
271
Quantitative Investment Management
Virginia
$1.27M +$965K +12,615 New
HC
272
Henshaw Capital
Massachusetts
$1.19M -$197K -2,572 -18%
HS
273
HighVista Strategies
Massachusetts
$1.17M -$753K -9,845 -46%
PNC Financial Services Group
274
PNC Financial Services Group
Pennsylvania
$1.17M +$71.3K +933 +9%
TSS
275
Two Sigma Securities
New York
$1.15M +$873K +11,414 New

INSM Hedge Fund Activity: Q2 2025 in Review

516 of the 7,595 institutional investors tracked by Wall St. Rank reported a position in Insmed (INSM) for Q2 2025, worth a combined $21.2B — up 38% from $15.3B a quarter earlier.

Buyers outnumbered sellers: 131 funds opened new INSM positions and 52 closed out — a net gain of 79 holders — while 165 added to existing stakes and 189 trimmed.

The largest buyer was JP Morgan Chase, adding an estimated $710M. The largest seller was BlackRock, cutting an estimated $375M.

  • 516 institutional investors held Insmed (INSM) as of Q2 2025, up from 441 in Q1 2025.
  • Funds reported $21.2B of Insmed stock for Q2 2025, up 38% quarter-over-quarter.
  • 131 funds opened new Insmed positions in Q2 2025 and 52 closed out, a net change of +79 holders.
  • The largest Insmed buyer in Q2 2025 was JP Morgan Chase, an estimated $710M added.
  • The largest Insmed seller in Q2 2025 was BlackRock, an estimated $375M sold.

Based on aggregated 13F filings for Q2 2025.