Two Sigma Advisers’s Insmed INSM Stock Holding History

Two Sigma Advisers’s Portfolio INSM Stock Details INSM Fund Activity

Bought

Maintained

Sold

Quarter	Market Value	Status	Shares	Change in Stake	Trade Value	Portfolio Weight	Portfolio Position
2026 Q1	–	Sell	-395,000	Closed	-$68.7M	–	1047
2025 Q4	$68.7M	Buy	395,000 +343,700	+670%	+$62.7M	0.13%	156
2025 Q3	$7.39M	Buy	51,300 +33,800	+193%	+$4.14M	0.01%	597
2025 Q2	$1.76M	Sell	17,500 -139,700	-89%	-$10.7M	﹤0.01%	1191
2025 Q1	$12M	Sell	157,200 -169,300	-52%	-$13M	0.03%	476
2024 Q4	$22.5M	Sell	326,500 -66,200	-17%	-$4.77M	0.05%	283
2024 Q3	$28.7M	Buy	392,700 +97,300	+33%	+$7.18M	0.07%	250
2024 Q2	$19.8M	Sell	295,400 -421,000	-59%	-$16.3M	0.04%	338
2024 Q1	$19.4M	Buy	716,400 +87,200	+14%	+$2.44M	0.05%	354
2023 Q4	$19.5M	Sell	629,200 -196,200	-24%	-$5.09M	0.05%	339
2023 Q3	$20.8M	Buy	825,400 +256,300	+45%	+$5.86M	0.05%	298
2023 Q2	$12M	Buy	569,100 +120,100	+27%	+$2.28M	0.03%	436
2023 Q1	$7.66M	Buy	449,000 +140,000	+45%	+$2.72M	0.02%	641
2022 Q4	$6.17M	Buy	309,000 +119,500	+63%	+$2.31M	0.02%	694
2022 Q3	$4.08M	Buy	189,500 +84,700	+81%	+$2.03M	0.01%	835
2022 Q2	$2.07M	Sell	104,800 -75,900	-42%	-$1.59M	0.01%	1197
2022 Q1	$4.25M	Sell	180,700 -22,300	-11%	-$518K	0.01%	877
2021 Q4	$5.53M	Sell	203,000 -227,700	-53%	-$6.51M	0.01%	724
2021 Q3	$11.9M	Buy	430,700 +191,300	+80%	+$5.02M	0.03%	460
2021 Q2	$6.81M	Buy	239,400 +113,800	+91%	+$3.38M	0.02%	720
2021 Q1	$4.28M	Buy	125,600 +51,700	+70%	+$1.98M	0.01%	915
2020 Q4	$2.46M	Sell	73,900 -102,700	-58%	-$3.75M	0.01%	1146
2020 Q3	$5.68M	Buy	176,600 +55,200	+45%	+$1.59M	0.02%	721
2020 Q2	$3.34M	Buy	121,400 +25,400	+26%	+$602K	0.01%	965
2020 Q1	$1.54M	Sell	96,000 -15,900	-14%	-$377K	0.01%	1252
2019 Q4	$2.67M	Sell	111,900 -72,000	-39%	-$1.46M	0.01%	1092
2019 Q3	$3.24M	Buy	183,900 +69,900	+61%	+$1.35M	0.01%	923
2019 Q2	$2.92M	Buy	114,000 +91,400	+404%	+$2.55M	0.01%	1039
2019 Q1	$657K	Buy	+22,600	New	+$586K	﹤0.01%	1695
2018 Q4	–	Sell	-13,600	Closed	-$275K	–	2403
2018 Q3	$275K	Buy	13,600 +3,000	+28%	+$67.7K	﹤0.01%	1983
2018 Q2	$251K	Buy	10,600 +1,300	+14%	+$33.5K	﹤0.01%	2152
2018 Q1	$209K	Buy	+9,300	New	+$245K	﹤0.01%	2130
2017 Q4	–	Sell	-7,200	Closed	-$225K	–	2307
2017 Q3	$225K	Buy	+7,200	New	+$137K	﹤0.01%	2019
2016 Q3	–	Sell	-11,400	Closed	-$112K	–	2254
2016 Q2	$112K	Buy	+11,400	New	+$133K	﹤0.01%	1958
2013 Q3	–	Sell	-30,900	Closed	-$369K	–	2238
2013 Q2	$369K	Buy	+30,900	New	+$316K	0.01%	1562

Other funds holding INSM

JP Morgan Chase New York $1.56T AUM 27.86% 1-Year Est. Return

BlackRock New York $5.72T AUM 30.48% 1-Year Est. Return

DGM

Darwin Global Management St. Helier, Jersey $3.77B AUM 307.72% 1-Year Est. Return

Fidelity Investments Boston, Massachusetts $1.9T AUM 41.92% 1-Year Est. Return

VPM

Vanguard Portfolio Management Malvern, Pennsylvania $1.91T AUM

VCM

Vanguard Capital Management Malvern, Pennsylvania $4.04T AUM

BBA

Baker Bros. Advisors New York $17.4B AUM 131.5% 1-Year Est. Return

Artisan Partners Milwaukee, Wisconsin $62.3B AUM 26.25% 1-Year Est. Return

Invesco Atlanta, Georgia $1.02T AUM 30.18% 1-Year Est. Return

D.E. Shaw & Co New York $166B AUM 43.98% 1-Year Est. Return

Two Sigma Advisers's INSM Position: Q1 2026 in Review

Two Sigma Advisers sold out of Insmed (INSM) in Q1 2026, closing a stake of 395,000 shares — an estimated $68.7M sold.

Two Sigma Advisers first reported a position in INSM in Q2 2013 and held it in 34 quarters. The position peaked at $68.7M in Q4 2025. 669 funds tracked by Wall St. Rank hold INSM as of Q1 2026.

Two Sigma Advisers reported no remaining Insmed position as of Q1 2026 after selling out during the quarter.
Two Sigma Advisers sold 395,000 Insmed shares in Q1 2026, an estimated $68.7M.
Two Sigma Advisers first reported a position in Insmed in Q2 2013 and held it in 34 quarters.
Two Sigma Advisers's Insmed position peaked at $68.7M in Q4 2025.
669 funds tracked by Wall St. Rank held Insmed as of Q1 2026.

Based on Two Sigma Advisers's 13F filing for Q1 2026.